Aim: This study aims to find out the proinflammatory chemokines macrophage inflammatory protein (MIP)-1α and MIP-1β levels in gingival crevicular fluid (GCF) of primary, mixed, and permanent dentitions. Materials and Methods: GCF of 160 individuals (4–15 years of age) was collected by the extracrevicular method. They were categorized into four groups (40 per each group). Group I: subjects with primary dentition (4–5 years of age), Group II: 40 subjects in early transition period (6–8 years), Group III: 40 individuals in the late transition period (9–11 years), and Group IV: 40 individuals with permanent dentition (12–15 years). MIP-lα and MIP-1β levels were determined in the samples of GCF by ELISA method. Data were analyzed by software SPSS Version 20 (IBM SPSS Statistics for Windows, IBM Corp., Armonk, NY: USA). Results: MIP-1α and MIP-1β were detected in all samples. The highest mean MIP-1α and MIP-1β concentrations in GCF were detected in the early transition period, while the lowest concentrations were seen in primary dentition group. The chemokine levels were higher in girls than in boys in Group III. There was a substantial rise of MIP-1α and MIP-1β levels during eruption. Conclusions: Since levels of MIP-1α and MIP-1β in GCF are positively associated with tooth eruption, they may perhaps be deemed as novel biomarkers in the eruption process.

The Odontogenic keratocyst (OKC) is a developmental, non – inflammatory chronic cystic lesion, on radiograph it may be unilocular or multi locular OKC is a cyst of odontogenic origin, usually asymptomatic with an aggressive clinical behavior including a high recurrence rate and tendency to invade bone and adjacent soft tissues. Diagnosis is based on the clinical history, clinical appearance, and radiographs and histology. A case of odontogenic keratocyst involving the ramus of the mandible is presented in this article emphasizing on the characteristics and various features of OKC.

Iron deficiency anaemia is the most common nutritional deficiency disorder in children and is worldwide in distribution. It is characterised by fatigue, weakness, pallor and koilonychias. Thus oral physician play an important role in diagnosis and thereby prevention of anaemia, as oral manifestations may be the earliest feature of the condition. The purpose of this article is to present a case of iron deficiency anaemia of unknown cause in a 16 year old female child.

The pleomorphic adenoma is the most common benign tumor of the minor salivary glands and is comprised of epithelial and mesenchymal tissues. The majority of the salivary gland tumors occur in the second decade of life with a slight predilection for females. Clinically it presents as a firm or rubbery submucosal mass without ulceration or surrounding inflammation. Diagnosis is established on the clinical examination and histopathology, supplemented with plane radiographs, computerized tomography, and magnetic resonance imaging when necessary. Here, we report a case of pleomorphic adenoma of the hard palate in a 21-year-old female patient with a painless swelling in the left palatal region of nine months duration.

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