In vitro resistance of titanium and resorbable (poly l-co-dl lactic acid) osteosynthesis in mandibular body fracture

Rodríguez-Chessa, Jaime Giuseppe; Olate, Sérgio; Netto, Henrique Duque de Miranda Chaves; Nóia, Cláudio Ferreira; Moraes, Márcio de; Mazzonetto, Renato

doi:10.1016/j.ijom.2013.09.001

Cited by 11 publications

(5 citation statements)

References 27 publications

(27 reference statements)

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“…Mazzonetto et al reported the application of osteosynthesis screws for internal fixation of autogenous bone blocks extracted from the iliac crest, thereby avoiding the subsequent removal of the osteosynthesis for the installation of dental implants. The mechanical characteristics of these PLA/PGA screws have been evaluated for more than 15 years in the maxillofacial surgery literature, describing good results, similar to those obtained by titanium elements (Rodríguez-Chessa et al, 2014). In maxillofacial surgery, these osteosynthesis systems have been used in maxillofacial traumatology, orthognathic surgery and craniofacial surgery without presenting any changes in the bone repair mechanism of fractures or osteotomies (Ueki et al, 2012).…”

Section: Discussionmentioning

confidence: 95%

PLA/PGA and its co-Polymers in Alveolar Bone Regeneration. A Systematic Review

Parra

Moya

Rebolledo³

et al. 2019

Int. J. Odontostomat.

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PARRA, M.; MOYA, M. P.; REBOLLEDO, C.; HAIDAR, Z. S.; ALISTER, J. P. & OLATE, S. PLA/PGA and its co-polymers in alveolar bone regeneration. A systematic review. Int. J. Odontostomatol., 13(3): 258-265, 2019.ABSTRACT: The aim of this research was to perform a systematic review to identify the most frequent uses of PLA/ PGA in alveolar bone regeneration and their results. A study was designed to answer the question: What are the most frequent uses of PLA/PLGA and their copolymers in alveolar bone regeneration?. A systematic search was done on MEDLINE, EMBASE and LILACS from April 1993 to December 2017. The search string used on MEDLINE was: (((polylactic acid) OR PLA) OR PLA-based copolymers) OR PLA blends) OR PLA scaffolds)) AND ((("Bone Regeneration"[Mesh]) OR bone regeneration) OR guided bone regeneration). The search was complemented by a manual review of the references from the articles included. Most of the studies selected were weak and, regarding the most frequent uses of PLA/PGA, 13 studies used it as a resorbable membrane, two as an absorbable mesh, one as an absorbable screw and three as filling material. Based on our results, the authors consider that PLA/PGA requires a delicate relation between the mechanical resistance and the degradation process. PLA/PGA does not interrupt bone regeneration; however, the influence in cellular events related to bone regeneration and later osseointegration have not been identified.

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Section: Discussionmentioning

confidence: 95%

PLA/PGA and its co-Polymers in Alveolar Bone Regeneration. A Systematic Review

Parra

Moya

Rebolledo³

et al. 2019

Int. J. Odontostomat.

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“…Factors like a long waiting time before stabilization of the fracture, use of tobacco and tooth extractions have been cited as risk factors for complications in fracture healing, including nonunion (Hsieh et al, 2019). For these reasons, the quality and quantity of the fixation material are critical through their ability to support the immobilization of the segments and provide sufficient mechanical stability for the patient and the type of fracture beingtreated (Rodriguez Chessa et al, 2014;de Medeiros et al, 2016;Meram et al, 2018).…”

Section: Discussionmentioning

confidence: 99%

Stability as a Key Factor for Bone Repair in Nonunion of Mandibular Osteotomy

et al. 2020

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Stability is necessary to ensuring proper bone repair after osteotomies and fractures. The aim of this research was to analyze how the repair of pseudoarthrosis sites was affected by different conditions in related to soft tissue. An experimental study was designed with 18 New Zealand rabbits. Six study groups were formed. An osteotomy was performed on the mandibular body of each animal and muscle was installed at the osteotomy site to model pseudoarthrosis. Fixation by surgery was then carried out, using plates and screws. The animals were submitted to euthanasia after 21, 42 and 63 days to make a descriptive comparison of the histological results. No animal was lost during the experiment. In all the samples, bone formation was observed with different degrees of progress. Defects treated with or without removal of the tissue involved in pseudoarthrosis presented comparable bone repair, showing that stability of the bone segments allows the repair of adjacent tissue. In some samples cartilaginous tissue was associated with greater bone formation. Stabilization of the fracture is the key in bone repair; repair occurs whether or not the pseudoarthrosis tissue is removed.

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“…It is precisely why PLA is a valuable material, with another application in manufacturing of fixation screws [41]. The complications associated with biodegradable PLA screws are relatively low, along with good mechanical characteristics, similar to those obtained by widely used titanium screws [42]. Matsuo et al [26] were the first authors who reported the use of custom-made biodegradable PLA mesh reinforced with hydroxyapatite (HA) in the reconstruction of large defects of the mandible.…”

Section: Lateral Compression Testmentioning

confidence: 99%

Mechanical Characteristics of Individualized Biodegradable Augmentation Scaffold—In Vitro Pilot Study

Bjelica,

Prpić,

Drvar

et al. 2024

Materials

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The alveolar ridge reconstruction of vertical and combined bone defects is a non-predictable procedure with varying percentages of success. The greatest challenge for vertical and combined bone augmentation is to maintain mechanical stability of the bone graft; therefore, it is mandatory to provide and preserve space for bone regeneration. The development of biomaterials and 3D printing has enabled the use of polymer scaffolds in the reconstruction of alveolar ridge defects. The aim of this pilot study was to evaluate the mechanical characteristics of an innovative individualized biodegradable polylactic acid (PLA) scaffold, under dynamic conditions, simulating biodegradation and the influence of masticatory forces. After the design and 3D printing of PLA scaffolds, two groups of 27 scaffolds were formed according to the compression testing procedure. The compression tests were performed in occlusal and lateral directions. In each of the two groups, nine subgroups of three scaffolds were formed for different testing periods during in vitro degradation with a total period of 16 weeks. Results showed that biodegradation and load application had no significant influence on mechanical characteristics of tested scaffolds. It can be concluded that simulated masticatory forces and biodegradation do not significantly influence the mechanical characteristics of an individualized biodegradable augmentation scaffold.

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In vitro resistance of titanium and resorbable (poly l-co-dl lactic acid) osteosynthesis in mandibular body fracture

Cited by 11 publications

References 27 publications

PLA/PGA and its co-Polymers in Alveolar Bone Regeneration. A Systematic Review

PLA/PGA and its co-Polymers in Alveolar Bone Regeneration. A Systematic Review

Stability as a Key Factor for Bone Repair in Nonunion of Mandibular Osteotomy

Mechanical Characteristics of Individualized Biodegradable Augmentation Scaffold—In Vitro Pilot Study

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