Quality of life and female sexual function after skinning vulvectomy with split-thickness skin graft in women with vulvar intraepithelial neoplasia or vulvar Paget disease
Abstract:Skinning vulvectomy with split-thickness skin graft is a feasible technique yielding good results in terms of quality of life and sexual function. It enables occult cancer to be diagnosed in patients with VIN or Paget disease.
“…27 However, in the two studies that reported total FSFI scores in vulvar cancer patients, these scores were higher than in our study group. 21,25 Also, the total FSFI scores and all subdomains of our study group were worse than those of healthy Dutch women reported by Ter Kuile et al 14 (mean 17.1 vs 31.2). However, the women reported by Ter Kuile et al 14 are younger in our study group (mean age 65.5 vs 27.1 years).…”
Patients who underwent vulvar reconstructive surgery with lotus petal flaps seem to have a lower QoL compared with healthy women. Patients report more pain during sexual activity but are satisfied about their sexual functioning. These results should be included in preoperative counseling and follow-up of future patients eligible for vulvar reconstruction with a lotus petal flap.
“…27 However, in the two studies that reported total FSFI scores in vulvar cancer patients, these scores were higher than in our study group. 21,25 Also, the total FSFI scores and all subdomains of our study group were worse than those of healthy Dutch women reported by Ter Kuile et al 14 (mean 17.1 vs 31.2). However, the women reported by Ter Kuile et al 14 are younger in our study group (mean age 65.5 vs 27.1 years).…”
Patients who underwent vulvar reconstructive surgery with lotus petal flaps seem to have a lower QoL compared with healthy women. Patients report more pain during sexual activity but are satisfied about their sexual functioning. These results should be included in preoperative counseling and follow-up of future patients eligible for vulvar reconstruction with a lotus petal flap.
“…Some of the limitations of the present study include the small size of the study group, its design as a retrospective study, the low cost‐effectiveness of the treatment, and the risk of missing occult microinvasive cancer . Indeed, the procedure of PDT and the PSZs were not covered by public insurance in Korea.…”
Section: Discussionmentioning
confidence: 97%
“…Currently, the incidence of VIN is increasing in developed countries, and the disease is mainly affecting young women . Radical surgery for the treatment of these diseases is too extensive; while destructive surgery results in a good prognosis, its consequences can also include genital mutilation and disfiguration, sexual dysfunction, and psychosocial problems for patients . The preservation of normal genital anatomy and function is of importance to patients.…”
“…The goals of reconstruction are to preserve the vaginal and urethral introitus, prevent delays in adjuvant treatment, and minimize donor site morbidity. Numerous techniques have been described in the literature, including healing by secondary intention, skin grafts, and locoregional flaps (Dias‐Jr et al, 2019; Galandiuk, Jorden, Mahid, McCafferty, & Tobin, 2005; Hage, Lange, Zijlmans, & van Beurden, 2018; Hand et al, 2018; Hashimoto, Abe, & Nakanishi, 2014; Hollenbeck et al, 2011; Lavoué et al, 2013; Mercut et al, 2018; Stephanie et al, 2019; Tan, Kang, Tay, & Por, 2014). Many of these options require well‐vascularized recipient or donor site tissues, which is often not the case in patients who have had prior radiation and surgical therapy.…”
Reconstruction following total vulvectomy is a reconstructive challenge. Previously described techniques typically require bilateral flaps and the associated donor site morbidity. We present a case of reconstruction after radical total vulvectomy using a single split anterolateral thigh (ALT) perforator flap with a design that optimizes perfusion while allowing for primary donor site closure. A 68‐year‐old female with a history of vulvar squamous cell carcinoma who had previously undergone vulvectomy and radiation therapy presented with local recurrence. The patient required a radical total vulvectomy, resulting in a 12 × 10 cm vulvar defect. A 2‐perforator ALT flap (25 × 7 cm) was harvested, split transversely, and then inset in a circumferential manner around the vulva. This approach contrasts with previous reports, which split the ALT flap longitudinally or centrally, and can compromise perfusion and/or preclude primary donor site closure. The patient healed without complication with 6 months of follow‐up. The described approach allows for total vulvectomy reconstruction using a single ALT flap with a perforator configuration that maximizes perfusion while obviating the need for donor site grafting.
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