Liquorice root extracts as potent cariostatic agents in pediatric practice

Jain, Eesha; Pandey, Ramesh Kumar; Khanna, Ranjana S.

doi:10.4103/0970-4388.117964

Cited by 22 publications

(9 citation statements)

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“…This transient increase in salivary pH level immediately after brushing might be due to increased salivary secretion due to stimulation of parotid gland secretion by substances present in the toothpastes such as Pilu ( Salvadora persica ), Neem (A zadirachta indica ) which are present in Dant Kanti and Himalaya Complete Care toothpaste [11]. Organoleptic properties of liquorice ( Glycyrrhiza glabra ) and cinnamon ( Cinnamomum verum ) which are present in Vicco Vajradanti stimulate the salivary flow and this in turn helps to raise the pH of the saliva [12], [13]. Salivary stimulation due to act of brushing increases salivary flow rate; also release of calcium and phosphorous ions from toothpastes itself as well as antibacterial activity against acid producing bacteria in saliva might have helped to raise the pH of the saliva [14].…”

Section: Discussionmentioning

confidence: 99%

Efficacy of herbal toothpastes on salivary pH and salivary glucose – A preliminary study

Khairnar

Dodamani

Karibasappa

et al. 2017

Journal of Ayurveda and Integrative Medicine

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Due to dearth of literature on the effect of herbal toothpaste on saliva and salivary constituents, the present study was undertaken to evaluate and compare the effect of three different herbal toothpastes with the focus on on salivary pH and salivary glucose. Forty five subjects in the age group of 19–21 years were randomly divided into 3 groups (15 in each group) and were randomly intervened with three different herbal toothpastes (Dant Kanti, Himalaya Complete Care and Vicco Vajradanti). Unstimulated saliva samples were collected before and after brushing and salivary glucose and pH levels were assessed at an interval of one week each for a period of 4 weeks starting from day 1. All the three toothpastes were effective in reducing the overall (p < 0.05) levels as well as levels of salivary glucose from pre-brushing to post-brushing at each interval (p < 0.05) and in increasing the overall levels as well as levels of salivary pH (p < 0.05) from pre-brushing to post-brushing at each interval. Herbal toothpastes were effective in reducing salivary levels of glucose and improving pH of the saliva.

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Section: Discussionmentioning

confidence: 99%

Efficacy of herbal toothpastes on salivary pH and salivary glucose – A preliminary study

Khairnar

Dodamani

Karibasappa

et al. 2017

Journal of Ayurveda and Integrative Medicine

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“…The advantage of this system is that instead of numerous portions of warm solvent being passed through the sample, just a single batch of solvent is recycled. 19 Jain et al 20 affirmed that both aqueous and ethanolic liquorice extracts are potent cariostatic agents and are found to be palatable by child patients. A similar in vitro study was performed by Ajagannanavar et al 21 to evaluate the effect of aqueous and alcoholic licorice ( Glycyrrhiza glabra ) root extract against S. mutans and Lactobacillus acidophilus in comparison to chlorhexidine and concluded that the inhibitory effect shown by alcoholic liquorice root extract against S. mutans and L. acidophilus was superior when compared with that of aqueous form and chlorhexidine.…”

Section: Discussionmentioning

confidence: 99%

Efficacy of Liquorice and Propolis Extract Used as Cavity Cleaning Agents against Streptococcus mutans in Deciduous Molars Using Confocal Microscopy: An In Vitro Study

Mali¹,

Tyagi²,

Godbole³

et al. 2019

International Journal of Clinical Pediatric Dentistry

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Background/introductionCavity disinfection before restoration aids in reducing the number of residual bacteria, thus, decreasing the rate of secondary caries. Propolis, at low concentrations, inhibits the growth of cariogenic bacteria. Liquorice roots are known to have antimicrobial, anti-inflammatory, and antioxidant properties.Aim and objectivesEvaluation and comparison of antimicrobial efficacy of liquorice and propolis extract gels used as cavity cleaning agents against Streptococcus mutans in deciduous molars by confocal laser scanning microscopy (in vitro study).Materials and methodsLiquorice and propolis extracts were converted into gels after recording the minimum inhibition concentration. Class I cavity was prepared on 135 extracted deciduous molars and subjected to inoculation with S. mutans. Teeth were randomly divided into groups I, II, and III which were treated with gels of liquorice, propolis, and distilled water, respectively, for 60, 120, and 180 seconds each. Specimens were sectioned and stained with fluorescent dyes and observed under a confocal laser scanning microscopy (CLSM). The data obtained were statistically evaluated.ResultsThe mean nonviable/viable bacterial count and the depth of penetration were found to be maximum in group I and minimum in group III. A statistically significant difference was found to be between groups I and II and groups I and III, while with groups II and III, it was nonsignificant at all 60, 120, and 180 seconds. The bacterial depth penetration between groups I and II at 180 seconds was nonsignificant.Conclusion and clinical significanceThough liquorice showed better antimicrobial potential as compared to propolis extract, both can be used efficiently as cavity disinfectants.How to cite this articleGodbole E, Tyagi S, et al. Efficacy of Liquorice and Propolis Extract Used as Cavity Cleaning Agents against Streptococcus mutans in Deciduous Molars Using Confocal Microscopy: An In Vitro Study. Int J Clin Pediatr Dent 2019;12(3):194–200.

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“…Root of licorice plant has several useful pharmacological properties such as anti-inflammatory, antiviral, antimicrobial and anticancer activities in addition to immunomodulatory, hepatoprotective and cardioprotective effects. [ 11 ] Sedighinia et al stated that GG can be used for the treatment of various oral diseases (periodontal, endodontic and dental caries infection). [ 12 ] In the current study, minimal inhibitory concentration (MIC) of GG was 15% at 1:2 dilution, which was in consonance with other study.…”

Section: Discussionmentioning

confidence: 99%

Antiadherence and antimicrobial property of herbal extracts (Glycyrrhiza glabra and Terminalia chebula) on Streptococcus mutans: An in vitro experimental study

Bhadoria

Gunwal

Suryawanshi

et al. 2019

J Oral Maxillofac Pathol

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Liquorice root extracts as potent cariostatic agents in pediatric practice

Abstract: The study affirms that both aqueous and ethanolic liquorice extracts are potent cariostatic agents and are found to be palatable by child patients.

Cited by 22 publications

References 0 publications

Efficacy of herbal toothpastes on salivary pH and salivary glucose – A preliminary study

Efficacy of herbal toothpastes on salivary pH and salivary glucose – A preliminary study

Efficacy of Liquorice and Propolis Extract Used as Cavity Cleaning Agents against Streptococcus mutans in Deciduous Molars Using Confocal Microscopy: An In Vitro Study

Antiadherence and antimicrobial property of herbal extracts (Glycyrrhiza glabra and Terminalia chebula) on Streptococcus mutans: An in vitro experimental study

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