Quality of Life and Nutritional Status Among Cancer Patients on Chemotherapy

Abstract

GLOBAL QUALITY OF LIFE AND ITS PARAMETERS: physical state, role, emotional state, cognitive functioning, cancer fatigue, nausea and vomiting, pain, insomnia, and loss of appetite were statistically different across all Subjective Global Assessment groups. Moreover, there was no difference between financial difficulties, social functioning, constipation and diarrhea among the Subjective Global Assessment groups.

Influence of chemoradiotherapy on nutritional status, functional capacity, quality of life and toxicity of treatment for patients with cervical cancer

“…The QoL summary score in the study population showed a positive association between NS at T0 and T1, with a significant reduction according to worsening of the NS. Data of the present study corroborate with recent literature, which has shown lower QoL scores among cancer patients presenting weight loss or malnutrition . Malnutrition is now considered an independent factor for the deterioration of QoL, and a recent systematic review concluded that poor NS is significantly associated with the QoL reduction in cancer patients, independently of the tumour site …”

“…The gastrointestinal toxicities such as nausea and diarrhoea were the most common, corroborating with other studies that report an elevated incidence of toxicity in gynaecologic tumours, in addition to the association between severity and decline of the NS . The gastrointestinal symptoms can negatively impact the NS reducing of nutrient intake and accelerating muscular degradation, with worsened physical capacity and consequent QoL …”

“…5 An elevated incidence of toxicity is described in chemoradiotherapy, with hematologic 6,7 and gastrointestinal toxicity being the most commonly found in these cases. 8,9 The presence of symptoms having a nutritional impact, such as nausea, vomiting and anorexia, can reduce nutritional intake and accelerate muscle loss 10,11 which results in impaired muscle function. 12 This depletion may be reflected in different functional tests, such as hand grip strength (HGS), a good indicator of nutrition status and clinical outcome.…”

EORTC QLQ-OES 18 module strategy for assessment of quality of life in esophageal cancer patients

“…Eating difficulties, pain, fatigue, nausea and vomiting, and appetite loss were clinically relevant and statistically significant worse symptoms experienced among those with a post-operative weight loss [7] . Our results are in line with studies which report that approximately 3 months after esophagectomy, patients report worse functional aspects of QOL (physical, social, role and cognitive function) and more problems with fatigue, nausea and vomiting, pain, appetite loss, diarrhea, dry mouth and loss of taste than before treatment [5][6][7][8][9] . With the goal of improving postoperative outcomes, there has been a trend towards the increased use of trimodality therapy (induction chemotherapy and radiation therapy, followed by surgery) and minimally invasive esophagectomy (MIE) for esophageal resection; although their advantages and cost effectiveness remains debatable [10,11] .…”

Socio-Demographic, Somatic and Disease Profile of Cancer Patients in Tertiary Care Centres of a City in Karnataka, India

“…7 Other factors such as stage of cancer at diagnosis, cancer cachexia, treatment associated Nutrition Impact Symptoms (NIS) and poor nutritional status have a negative impact on the functional status of cancer patients. [8][9] Recent data of the Population Based Cancer Registries (PBCRs), India, on cancer prevalence reported lung, mouth, oesophagus and stomach in men and; breast and cervix in women as the leading cancer sites. 10 According to the National Cancer Registry Programme (NCRP) report 2012-14 on the tobacco related cancers, lung cancer followed by cancers of the oesophagus and mouth were leading sites in both the genders across the country.…”