Fungal rhinosinusitis: A prospective study in a University hospital of Uttar Pradesh

Abstract

Mycological profile of rhinosinusitis in Lucknow was thus evaluated. Histopathological and microbiological findings reported 21 cases of fungal rhinosinusitis among 100 suspected cases of rhinosinusitis.

Evidence for a ‘preinvasive’ variant of fungal sinusitis: Tissue invasion without angioinvasion

“…We present two related cases of fungal sinusitis outside of the traditional classification system ( Table 1 ). 1 , 2 , 3 , 4 , 5 , 6 Both cases presented acutely in both immunocompromised and immunocompetent individuals. The fungal disease was circumscribed to the sphenoid sinus, and the affected mucosa was locally devitalized/abnormal in quality.…”

“…Fungal sinusitis is classically divided into non-invasive (fungal ball, allergic fungal sinusitis, saprophytic fungal growth) and invasive forms (acute invasive fungal sinusitis, chronic IFS, chronic granulomatous fungal sinusitis) ( Table 1 ). 1 , 2 , 3 , 4 , 5 , 6 Invasive fungal sinusitis (IFS) is a life-threatening entity involving fungal species such as Mucor and Aspergillus that, in the immunosuppressed host, become invasive, and extend beyond the bony boundaries of the sinuses and skull base. 1 , 2 , 6 The morbidity and mortality associated with IFS are high, especially for acute IFS.…”

Epidemiology of chronic rhinosinusitis, selected risk factors, comorbidities, and economic burden

“…A clear majority of the literature in this context originates from Asia: fungal sinusitis in China [ 30 ] and India [ 39 ] is chronically invasive in about one third of the cases and non-invasive in about two third. In general a significant increase of the articles on this subtype is observed in the literature [ 39 ].…”

“…They report about suffering from the symptoms for less than three years that often occur as headaches and bloody nasal secretion [ 30 ]. In contrast, males seem to be affected more often in India according to the majority of the published studies (♂:♀=1.8:1 [ 40 ]; 1.33:1 [ 39 ]; 0.8:1 [ 44 ]).…”

“…Based on representative surveys of the population, the prevalence of chronic headaches (>15 days per year) is estimated to 2.14% in Norway. The complaints of 0.33% of the total sample or 15.3% of the headache patients could be confirmed as originating from CRS [ 39 ]. Thus, CRS is the second most common genesis of chronic headaches after drug-induced headaches [ 39 ].…”