Using High-sensitivity Troponin T: The Importance of the Proper Gold Standard

Santaló, Miguel; Martı́n, Alfonso; Velilla, J.; Povar, Javier; Temboury, Francisco; Balaguer, Jose Vicente; Muñoz, M Romo; Calmarza, Pilar; Ortiz, Carmen; Carratalá, Arturo; Gich, Ignasi; Mercé, J; Jaffe, Allan S.; Ordóñez-Llanos, Jordi

doi:10.1016/j.amjmed.2013.03.003

Cited by 53 publications

(39 citation statements)

References 29 publications

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“…7 The widespread use of troponin assay in emergency rooms is a significant diagnostic challenge when levels of the biomarker are abnormal in patients with symptoms who could have ischemia or ischemia equivalents, but who have concomitant diseases in which troponin elevation has been described. [8][9][10] In order to establish that troponin elevation is due to ACS, it has been proposed that percent increases or absolute changes 11 be identified through serial measurements. 12 In clinical practice, ACS is usually ruled out in patients with troponin elevation based on the medical history, electrocardiogram (ECG), overall patient context, and other additional examinations performed during the emergency room or hospital stay.…”

Section: Introductionmentioning

confidence: 99%

Troponin Elevation in Patients Without Acute Coronary Syndrome

Bardajı́

Cediel

Carrasquer

et al. 2015

Revista Española de Cardiología (English Edition)

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Section: Introductionmentioning

confidence: 99%

Troponin Elevation in Patients Without Acute Coronary Syndrome

Bardajı́

Cediel

Carrasquer

et al. 2015

Revista Española de Cardiología (English Edition)

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“…Interpretación del valor delta 54 , o tambié n, en IM diagnosticados por presentar algú n valor de TnTc-es superior al p99, pero sin cambios en la ciné tica 51 .…”

Section: Valor Delta óPtimounclassified

Interpretación clínica de la determinación de troponina T de elevada sensibilidad

2015

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“…Las cifras anormales de este biomarcador en pacientes con síntomas isqué-micos o equivalentes isquémicos pueden presentarse también en enfermedades concomitantes, donde se señala su elevación (15)(16)(17) . Sin embargo, se considera que por sí sola, la troponina es incapaz de determinar con exactitud el mecanismo del daño al miocardio (18) .…”

Section: Introductionunclassified

Riesgo de infarto de miocardio en pacientes críticos mayores de 65 años

Morocho¹,

Bayona²

2017

An Fac med

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Riesgo de infarto de miocardio en pacientes críticos mayores de 65 añosMethods: Data was collected from emergency medical records of 140 critically ill patients over 65 years old. The variables age, sex, medical history and priority of attention were analyzed. The relationships between a positive value of troponin and electrocardiographic abnormalities were detailed. The prevalence ratio and the prevalence OR were calculated. Main outcome measures: Relationship between positive value of troponin and electrocardiographic abnormalities. Results: Troponin tests in men and women above the upper reference value accounted for 50 and 60% respectively, both on admission to the emergency service and in the control obtained between 6 to 12 hours later. About 70% of patients with ischemic type alterations in the electrocardiogram (ECG) were troponin positive for myocardial necrosis. The prevalence ratio (RP) and the prevalence OR (ORP) for ischemic ECG and positive troponin at admission were respectively 1.779 (CI 95%: 1.215-2.604) and 3.7 (CI 95%: 1.662-8.44), respectively. For the ECG and positive troponin control, the RP was 1.969 (CI 95%: 1.345-2.884), and the ORP was 5.101 (CI 95%: 2.187-11.9). Conclusions: An increased risk of myocardial infarction was found in critical patients over 65 years old who presented electrocardiographic alterations of ischemic type during their stay in the emergency service.

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Using High-sensitivity Troponin T: The Importance of the Proper Gold Standard

Cited by 53 publications

References 29 publications

Troponin Elevation in Patients Without Acute Coronary Syndrome

Troponin Elevation in Patients Without Acute Coronary Syndrome

Interpretación clínica de la determinación de troponina T de elevada sensibilidad

Riesgo de infarto de miocardio en pacientes críticos mayores de 65 años

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