Febrile Illness in a Young Traveler: Dengue Fever and its Complications

Duber, Herbert C.; Kelly, Stephen M.

doi:10.1016/j.jemermed.2013.03.021

Cited by 7 publications

(5 citation statements)

References 21 publications

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“…Global trade and tourism transported the dengue virus from endemic areas to other parts of the world, where dengue became a global pandemic affecting not only tropical countries but also some regions of Europe and North America [ 3 – 6 ]. Cases of dengue have been detected among travelers to endemic areas upon their return home to disease-free regions, often with a late diagnosis followed by severe systemic complications [ 7 – 9 ].…”

Section: Introductionmentioning

confidence: 99%

Dengue-associated acute kidney injury

Oliveira

Burdmann

2015

Clin Kidney J

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Dengue is presently the most relevant viral infection transmitted by a mosquito bite that represents a major threat to public health worldwide. Acute kidney injury (AKI) is a serious and potentially lethal complication of this disease, and the actual incidence is unknown. In this review, we will assess the most relevant epidemiological and clinical data regarding dengue and the available evidence on the frequency, etiopathogenesis, outcomes and treatment of dengue-associated AKI.

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Section: Introductionmentioning

confidence: 99%

Dengue-associated acute kidney injury

Oliveira

Burdmann

2015

Clin Kidney J

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“…To reduce the possibility of infection, travellers should be informed about the risk of being infected with DENV and the preventive measures avoiding mosquito bites. On the other hand a sensitive surveillance system to identify and confirm suspected travellers in the shortest possible time is very important; in this regard clinicians should have knowledge of dengue symptoms, clinical management and its potential complications (9). The outcome of infection with DENV varies from asymptomatic to dengue fever, dengue hemorrhagic fever (DHF), and dengue shock syndrome (DSS).…”

Section: Discussionmentioning

confidence: 99%

An Imported Case of Dengue Fever in Iran, 2015

Baniasadi¹,

Salehi‐Vaziri²,

Jalali³

et al. 2016

Iran J Virol

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Background: Dengue fever is a mosquito-borne disease which is not known to be endemic in Iran. Case Report: In October 2015, a 32-year-old Iranian woman was admitted with acute unexplained high-grade fever, headache, pain, rash, diarrhea, leukopenia and elevated liver enzymes after returning from India. Serological and molecular analysis for Dengue virus (DENV) infection revealed positive IgM, negative IgG and positive reverse transcriptase-PCR (RT-PCR) Results: PCR product was sequenced and the phylogenetic analysis showed a DENV 2, genotype 4 strain with high similarity to other isolates reported from India. Conclusion: Considering that DENV is one of the most common infections among travelers, an integrated surveillance system is strictly recommended in dengue non endemic countries.

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“…A new classification made by the World Health Organization (WHO) society in 2009 classifies dengue as dengue without warning signs, dengue with warning signs, and severe dengue (SD) . Plasma leakage and virus pathogenesis are responsible for several serious complications: shock, cardiomyopathy, encephalopathy, encephalitis, hepatic damage, and neural manifestations . Spontaneous splenic rupture is known as a complication of infectious diseases such as malaria, mononucleosis, and hematopoietic disorder .…”

Section: Introductionmentioning

confidence: 99%

“…1 Plasma leakage and virus pathogenesis are responsible for several serious complications: shock, cardiomyopathy, encephalopathy, encephalitis, hepatic damage, and neural manifestations. [3][4][5] Spontaneous splenic rupture is known as a complication of infectious diseases such as malaria, mononucleosis, and hematopoietic disorder. [6][7][8] The aim of this study was to systematically review all relevant studies reporting splenic rupture related to dengue infection to summarize demography, clinical picture, and time of splenic rupture during illness, management, and outcome.…”

Section: Introductionmentioning

confidence: 99%

Systematic review of spontaneous splenic rupture in dengue‐infected patients

Radwan

Khattab

Mahmoud

et al. 2019

Reviews in Medical Virology

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Summary Dengue infection varies from a mild febrile form to more severe disease with plasma leakage, shock, and multiorgan failure. Several serious complications such as cardiomyopathy, encephalopathy, encephalitis, hepatic damage, and neural manifestations cause organ damage in dengue infection. Splenic rupture, a less well known but life‐threatening complication, can occur in dengue. The mechanism of splenic rupture in dengue is still unclear. Optimal therapeutic management is required to save the lives of patients with this complication. The objective of this study was to conduct a systematic review of studies documenting the development of spontaneous nontraumatic splenic rupture in patients with dengue infection. In March 2018, a search was conducted systematically in nine electronic databases, in addition to hand‐ searching. A total of 127 references were exported to Endnote; 47 references remained after removing duplicates. Finally, 16 reports met the inclusion criteria and represented 17 cases. All articles were evaluated and data extracted according to predefined criteria: number of cases, age, sex, severity of dengue disease, days of illness before admission, methods of definitive diagnosis, timing of the event, and management and outcome. A total of 17 individual patients including 13 males and four females were found. Most of the patients were young adults (ranging from 20 to 52 years) and diagnosed with computed tomography scan and managed with splenectomy. Four cases were fatal. Pathological splenic rupture in dengue is a rare, life‐threatening condition where timely management can achieve a favorable outcome.

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Febrile Illness in a Young Traveler: Dengue Fever and its Complications

Cited by 7 publications

References 21 publications

Dengue-associated acute kidney injury

Dengue-associated acute kidney injury

An Imported Case of Dengue Fever in Iran, 2015

Systematic review of spontaneous splenic rupture in dengue‐infected patients

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