Effect of a Discharge Medication Intervention on the Incidence and Nature of Medication Discrepancies in Older Adults

Maanen, A. Clara Drenth van; Wilting, Ingeborg; Jansen, Paul A. F.; Marum, Rob J. van; Egberts, Toine C. G.

doi:10.1111/jgs.12117

Cited by 5 publications

(2 citation statements)

References 10 publications

(16 reference statements)

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“…We have observed that research has been accelerating in the field of medication safety post-hospital discharge since the year 2010. A previous review published in 2010 [20] found that ADEs post-hospital discharge affected 20% of elderly patients (n = 1) [55], while our review updates and Information mentioned in the letter to the editor [100] was used in the quality assessment strengthens this evidence with a rate of 18.7-37% of discharged elderly (n = 4) [24,55,61,94]. Our review found that the median rate of MEs and ADEs is higher in the elderly population.…”

Section: Main Findingssupporting

confidence: 71%

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Prevalence and Nature of Medication Errors and Medication-Related Harm Following Discharge from Hospital to Community Settings: A Systematic Review

2020

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Background Little is known about the epidemiology of medication errors and medication-related harm following transition from secondary to primary care. This systematic review aims to identify and critically evaluate the available evidence on the prevalence and nature of medication errors and medication-related harm following hospital discharge. Methods Studies published between January 1990 and March 2019 were searched across ten electronic databases and the grey literature. No restrictions were applied with publication language or patient population studied. Studies were included if they contained data concerning the rate of medication errors, unintentional medication discrepancies, or adverse drug events. Two authors independently extracted study data. Results Fifty-four studies were included, most of which were rated as moderate (39/54) or high (7/54) quality. For adult patients, the median rate of medication errors and unintentional medication discrepancies following discharge was 53% [interquartile range 33-60.5] (n = 5 studies) and 50% [interquartile range 39-76] (n = 11), respectively. Five studies reported adverse drug reaction rates with a median of 27% [interquartile range 18-40.5] and seven studies reported adverse drug event rates with a median of 19% [interquartile range 16-24]. For paediatric patients, one study reported a medication error rate of 66.3% and another an adverse drug event rate of 9%. Almost a quarter of studies (13/54, 24%) utilised a follow-up period post-discharge of 1 month (range 2-180 days). Drug classes most commonly implicated with adverse drug events were antibiotics, antidiabetics, analgesics and cardiovascular drugs. Conclusions This is the first systematic review to explore the prevalence and nature of medication errors and adverse drug events following hospital discharge. Targets for future work have been identified.

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Section: Main Findingssupporting

confidence: 71%

“…The included studies consisted of 41 published papers [23,24, and 13 conference abstracts [87][88][89][90][91][92][93][94][95][96][97][98][99]. One of the included conference abstracts [88] was combined with one letter to the editor [100]. All included studies were published in English.…”

Section: Overview Of Included Studiesmentioning

confidence: 99%