Retinal Vasoproliferative Tumors

Shields, Carol L.; Kaliki, Swathi; Al-Dahmash, Saad; Rojanaporn, Duangnate; Shukla, Saurabh; Reilly, Brad; Shields, Jerry A.

doi:10.1001/2013.jamaophthalmol.524

Cited by 94 publications

(85 citation statements)

References 22 publications

(10 reference statements)

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“…These tumors are also known to occur secondary to a variety of retinal insults such as inflammation (pars planitis), degenerative disorder (retintis pigmentosa), and trauma (retinal detachment surgery) [4,14]. Case 1 with a diagnosis of bilateral idiopathic retinal vasculitis had been treated with panretinal photocoagulation.…”

Section: Discussionmentioning

confidence: 99%

Reactive Retinal Astrocytic Tumor (Focal Nodular Gliosis): Report of the Clinical Spectrum of 3 Cases

et al. 2017

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Purpose: To report 3 cases providing insight into clinical progression of reactive retinal astrocytic tumor. Methods: The clinical, imaging, and when available, the cytologic features of 3 cases of reactive retinal astrocytic tumor (focal nodular gliosis) were reviewed. Results: A 6-year-old female, a 49-year-old man, and a 39-year-old man each developed a white retinal mass associated with laser photocoagulation, lattice degeneration, and treatment of a presumed vascular tumor, respectively. All tumors were white, circumscribed retinal masses that tended to be associated with exudation and either initially or eventually minimal vascularity. Conclusion: Reactive retinal astrocytic tumor can be observed in response to a degenerative, inflammatory, or ischemic retinal insult. Such tumors may progress after therapeutic intervention.

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Section: Discussionmentioning

confidence: 99%

Reactive Retinal Astrocytic Tumor (Focal Nodular Gliosis): Report of the Clinical Spectrum of 3 Cases

et al. 2017

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“…[8] It should be realized that VPTs and ERMs could be coincidental, as both can occur in older patients. [234] Finally, the occurrence of remote macular edema associated with VPT presumably results from the release of inflammatory cytokines that can also induce secondary inflammation-mediated ERM formation, similar to pars planitis and other uveitic conditions. [5]…”

Section: Discussionmentioning

confidence: 99%

“…Vasoproliferative tumor (VPT) is a benign retinal tumor that can lead to macular ERM in 50 of 252 patients (13%) of primary cases and in 15 of 82 patients (7%) of secondary cases. [2] Typically, this tumor appears as a reddish-pink, elevated mass located in the pre-equatorial region with mildly dilated retinal feeder vessels and often causing vision-threatening complications from lipid exudation, cystoid macular edema (CME), vitreous hemorrhage, retinal detachment, and ERM formation. [23] Treatment of VPT is focused toward tumor involution with resolution of these findings and visual recovery.…”

Section: Introductionmentioning

confidence: 99%

“…[2] Typically, this tumor appears as a reddish-pink, elevated mass located in the pre-equatorial region with mildly dilated retinal feeder vessels and often causing vision-threatening complications from lipid exudation, cystoid macular edema (CME), vitreous hemorrhage, retinal detachment, and ERM formation. [23] Treatment of VPT is focused toward tumor involution with resolution of these findings and visual recovery. [234] Methods of treatment include laser photocoagulation, photodynamic therapy, thermoablation, cryotherapy, plaque radiotherapy, and intravitreal steroid or anti-vascular endothelial growth factor (VEGF) injections alone or in combination.…”

Section: Introductionmentioning

confidence: 99%

“…[23] Treatment of VPT is focused toward tumor involution with resolution of these findings and visual recovery. [234] Methods of treatment include laser photocoagulation, photodynamic therapy, thermoablation, cryotherapy, plaque radiotherapy, and intravitreal steroid or anti-vascular endothelial growth factor (VEGF) injections alone or in combination. The most suitable choice depends on the tumor size and location as well as the related features.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Role of pars plana vitrectomy and membrane peel in vitreomacular traction associated with retinal vasoproliferative tumors

Castro-Navarro¹,

Saktanasate²,

Say³

et al. 2016

Oman J Ophthalmol

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To report a case of retinal vasoproliferative tumor (VPT) with secondary epiretinal membrane (ERM) formation and vitreo-macular traction managed by pars plana vitrectomy (PPV) and membrane peel. A 29-year-old male was referred for management of decreased vision in the right eye (OD) for 1 week. Presenting visual acuity was 20/50 Snellen feet (ft) OD, and fundus examination showed an ERM associated with a reddish-yellow mass in the inferotemporal quadrant with overlying exudation, hemorrhage, and subretinal fluid consistent with VPT, and cryotherapy was recommended. Two months later, there was complete tumor regression, but there was decreased vision from progressive vitreomacular traction to 20/400 ft. PPV with combined ERM and internal limiting membrane (ILM) peel were performed with resolution of vitreomacular traction and improvement of visual acuity to 20/50 ft at 6 months. PPV with combined ERM and ILM peel is effective for vision loss secondary to ERM and vitreomacular traction associated with retinal VPT.

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