Reactive Retinal Astrocytic Tumor (Focal Nodular Gliosis): Report of the Clinical Spectrum of 3 Cases

Singh, Arun D.; Soto, Hansell; Bellerive, Claudine; Biscotti, Charles V.

doi:10.1159/000455151

Cited by 14 publications

(6 citation statements)

References 20 publications

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“…RVPT are peripheral retinal vascular lesions that were described as a distinct clinical entity by Shields et al in a series of 12 patients in 1983 [ 6 ]. However, based on recently published reports on histopathology and molecular findings, ‘reactive retinal astrocytic tumor’ has been proposed as an alternate terminology, as the predominant components of the tumors are astrocytic and glial cells, with a minimal vascular component [ 7 ].…”

Section: Discussionmentioning

confidence: 99%

A case of primary vasoproliferative tumor with full-thickness macular hole

Rishi

Sreenivasan

2022

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A 53-year-old female presented with defective vision in the left eye of one week duration with a best-corrected visual acuity (BCVA) of 6/9. Fundus examination showed a primary retinal vasoproliferative tumor (RVPT) at the inferotemporal quadrant and a small full-thickness macular hole (MH). The patient underwent cryotherapy for RVPT, followed later by vitrectomy with internal limiting membrane peeling and gas tamponade. The tumor regressed and the MH was closed with BCVA of 6/9. RVPT can present with remote macular complications like epiretinal membrane, cystoid macular edema, macular exudates, and rarely full-thickness MH. Management should be directed towards the tumor as well as the complication.

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Section: Discussionmentioning

confidence: 99%

A case of primary vasoproliferative tumor with full-thickness macular hole

Rishi

Sreenivasan

2022

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“…Histologically, VPT has a vascular component and a glial component. Recent studies have demonstrated the predominance of the astrocytic and glial component, hence the proposal for the term “Reactive Retinal Astrocytic Tumors” [ 6 ].…”

Section: Discussionmentioning

confidence: 99%

Retinal vasoproliferative tumor in intermediate uveitis: A case report

Mahjoub

Ammar

Abdesslam

et al. 2020

Annals of Medicine and Surgery

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Introduction Retinal vasoproliférative tumors (VPTs) have been reported as uncommon complications of intermediate Uveitis. Case description A patient consulted for a gradually decreased vision in the right eye (RE). The examination of the RE found a corrected visual acuity at 20/100 with normal eye pressure measured. The anterior segment was deep and quiet and 2+ vitreous haze was found. Funduscopy showed a VPT. Retinal fluorescein angiography of the RE revealed macular cystoid edema also objectified by the Optical Coherence Tomography (OCT). Intermediate Uveitis was considered idiopathic. The patient received a cryoapplication and was put on oral corticosteroid therapy with improvement of visual acuity and a regress of both vitreous inflammation and cystoid macular edema. Conclusion The association of a VPT with intermediate uveitis represents a real diagnostic and therapeutic challenge and imposes rigorous care and monitoring strategy combining internist and ophthalmologist.

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“…Von astrozytären Hamartomen und erworbenen Astrozytomen der Netzhaut müssen reaktive astrozytäre Gliosen abgegrenzt werden. Die Bezeichnung für diese Entität in der Literatur ist uneinheitlich und umfasst Begriffe wie "pseudoneoplastic Gliosis of the Retina" [43], "focal nodular Gliosis" [50] oder "presumed solitary circumscribed retinal astrocytic Proliferation" [51].…”

Section: Klinik Diagnostikunclassified