Immune modulatory effects of Aloe arborescens extract on the piscine SAF-1 cell line

Picchietti, Simona; Bernini, C.; Belardinelli, Maria Cristina; Ovidi, Elisa; Taddei, Annarita; Guerra, Laura; Abelli, Luigi; Fausto, Anna Maria

doi:10.1016/j.fsi.2013.02.019

Cited by 29 publications

(20 citation statements)

References 71 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Immuno-nutritional benefits of A. vera have been demonstrated in several freshwater species such as rainbow trout (Oncorhynchus mykiss) [29e32], common carp (Cyprinus carpio) [33,20], Labeo rohita [34], Brycon amazonicus [35], and Sea bream (Sparu aurata) [36]. Taiwo et al [37]; and Jegede [38] reported histopathological effects of A. vera on tilapia species.…”

Section: Introductionmentioning

confidence: 99%

Dietary Aloe vera supplementation on growth performance, some haemato-biochemical parameters and disease resistance against Streptococcus iniae in tilapia (GIFT)

Gabriel

Qiang

et al. 2015

Fish & Shellfish Immunology

139

View full text Add to dashboard Cite

Section: Introductionmentioning

confidence: 99%

Dietary Aloe vera supplementation on growth performance, some haemato-biochemical parameters and disease resistance against Streptococcus iniae in tilapia (GIFT)

Gabriel

Qiang

et al. 2015

Fish & Shellfish Immunology

139

View full text Add to dashboard Cite

“…Picchietti et al (2013), investigaram a ação de componentes extraídos de A. arborescens em linhagens de células de peixes, encontrando ações antibióticas e antimicrobianas, devido sua influência positiva ao sistema imunológico. Além disso, relatos associados à A. barbadensis demonstram ação antioxidante e aumento da atividade imunológica em ratos com úlceras (Yu et al, 2009) e efeitos antidiabéticos e antioxidantes em ratos com diabetes (Abo-Yousseef & Messiha, 2013).…”

Section: Discussionunclassified

“…Os meios de cultura utilizados foram meio completo líquido e sólido, preparados segundo Pontecorvo et al (1953), Clutterbuck (1974) e Rocha (1997.…”

Section: Meios De Culturaunclassified

“…Pertencentes à Asphodelaceae (Wichtl, 2004) A. arborescens e A. barbadensis atuam beneficiando e protegendo o organismo por diferentes vias, por possuírem inúmeras propriedades, confirmadas pela comunidade científica, como imunoestimuladora (Lissoni et al, 2009), antioxidante (Ojha et al, 2001;Abo-youssef & Messiha, 2013), antitumoral (Tomasin & GomesMarcondes, 2011) e antidiabética/hipoglicemiante (Rajasekaran et al, 2004;Misawa et al, 2008;Aboyoussef & Messiha, 2013).…”

Section: Introductionunclassified

See 1 more Smart Citation

Efeito da Aloe arborescens Miller e da Aloe barbadensis Miller sobre o desenvolvimento vegetativo em Aspergillus nidulans

Berti

Pacheco

Rocha

2015

Rev. bras. plantas med.

View full text Add to dashboard Cite

RESUMO:A pesquisa de produtos naturais benéficos à saúde humana vem crescendo nos últimos 20 anos. Considerando que as plantas de Aloe são amplamente utilizadas pela população humana, em geral de maneira terapêutica, o objetivo deste estudo foi avaliar os efeitos de Aloe arborescens Miller e Aloe barbadensis Miller, sobre o desenvolvimento vegetativo de linhagens normais e mutantes de Aspergillus nidulans. Conídios da linhagem biA1methG1, MSE e CLB3 de A. nidulans, foram inoculados em meio completo sem (Controle) e com extratos das duas espécies incubados por 2, 4, 6 e 8 horas a 37ºC, no escuro. Foi analisado em microscópio óptico, 200 conídios de cada tratamento. Para o desenvolvimento das colônias, as linhagens foram inoculadas no centro das placas juntamente com o meio de cultura sólido e sobre a membrana de diálise, visando a medição do diâmetro e do peso. A análise estatística foi baseada no teste de Tukey e todos os procedimentos experimentais foram conduzidos em triplicata. Todas as linhagens apresentaram interferências positivas quando expostas às plantas de Aloe, porém, de maneira variada. Ambas as espécies aceleraram a germinação em todas as linhagens testadas e atuaram na redução significativa de conídios mortos e/ou malformados. Em relação ao desenvolvimento vegetativo, todos os dados referentes ao peso úmido e diâmetro corrigido dos tratamentos demonstraram progressos, contudo, a razão diâmetro/peso apresentou somente na linhagem MSE, ação favorável dos tratamentos naturais. As informações deste estudo sugerem benefícios de A. arborescens e A. barbadensis, justificando a importância e continuidade da investigação, para melhor elucidar os mecanismos de ação dessas plantas. Palavras-chave:Plantas medicinais, Babosa, Germinação, Crescimento vegetativo. ABSTRACT: Effects of the Aloe arborescens Millerand Aloe barbadensis Milleron over vegetative growth in the Aspergillus nidulans.The researches about natural products that arebeneficial to human health have been growing over the past 20 years. Since Aloe plants are broadly used by the general population, frequently due to therapeutic reasons, the objective of this study was to evaluate the effects of Aloe arborescens Millerand Aloe barbadensis Miller on the vegetative growth of normal and mutant strains of Aspergillus nidulans. The conidia of the biA1methG1, MSE and CLB3 strains of A. nidulans were inoculated in complete environment without (control) and with extracts of two species of Aloeincubated for 2, 4, 6 and 8 hours at 37°C. 200 conidia were analyzed by optical microscopy. For the development of the colonies, the strains were inoculated in the center of the plates together with the solid environment of the cultivation and over the dialysis membrane for measuring the diameter and weighing. The statistical analysis was based on the Tukey test and all experimental procedures were performed in triplicate. All strains showed positive interference when exposed to Aloe plants, however, through different manners. Both species have accelerated the germinat...

show abstract

“…These plants have several activities that are beneficial to the body, and in particular, their antioxidant (Ojha et al, 2011), antitumoral (Tomasin and Gomes-Marcondes, 2011), antidiabetic (Misawa et al, 2008;Abo-Youssef and Messiha, 2013), and immune system stimulating (Lissoni et al, 2009;Picchietti et al, 2013) functions stand out.…”

Section: Introductionmentioning

confidence: 99%

Antimutagenicity and antigenotoxicity of Aloe arborescens Miller and Aloe barbadensis Miller in Aspergillus nidulans and Wistar rats

2016

View full text Add to dashboard Cite

ABSTRACT. Medicinal plants such as Aloe arborescens Miller andAloe barbadensis Miller are used by the general population to treat various diseases. Therefore, the aim of this study was to evaluate the antimutagenicity of these two species using a methG1 system in Aspergillus nidulans and the comet assay in rats. The animals were treated with the plants at concentrations of 360 and 720 mg/kg body weight (1 and 2, respectively) by gavage for 14 days, followed by the administration of etoposide on treatment day 8. Blood samples were prepared for analysis of DNA damage. For the test in A. nidulans, the biA1methG1 lineage conidia were treated for 4 h with both plant species at concentrations of 4 and 8% (w/v). Then, they were washed and plated on a selective medium for frequency analysis of survival and mutation. The results of the comet assay showed that both plants were antigenotoxic compared to etoposide, which was not a typical response of methG1 systems, where only the highest concentration of plant extracts usually exhibit beneficial effects. This study demonstrates the potential antigenotoxicity and antimutagenicity of the Aloe plants tested and, therefore, supports their use as a form of preventive therapy and for health maintenance by the population.

show abstract

Immune modulatory effects of Aloe arborescens extract on the piscine SAF-1 cell line

Cited by 29 publications

References 71 publications

Dietary Aloe vera supplementation on growth performance, some haemato-biochemical parameters and disease resistance against Streptococcus iniae in tilapia (GIFT)

Dietary Aloe vera supplementation on growth performance, some haemato-biochemical parameters and disease resistance against Streptococcus iniae in tilapia (GIFT)

Efeito da Aloe arborescens Miller e da Aloe barbadensis Miller sobre o desenvolvimento vegetativo em Aspergillus nidulans

Antimutagenicity and antigenotoxicity of Aloe arborescens Miller and Aloe barbadensis Miller in Aspergillus nidulans and Wistar rats

Contact Info

Product

Resources

About