JBIR-107, a New Metabolite from the Marine-Sponge-Derived Actinomycete,<i>Streptomyces tateyamensis</i>NBRC 105047

Izumikawa, Miho; Kawahara, Teppei; Hwang, Ji‐Hwan; Takagi, Motoki; Shin‐ya, Kazuo

doi:10.1271/bbb.120832

Cited by 8 publications

(9 citation statements)

References 11 publications

(12 reference statements)

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“…CMS JV M18_3 associated with marine sponge Agelas sceptrum collected in Mona Island exhibited inhibitory activity on testosterone 5α-reductase [3,29]. Three new trichostatin analogs JBIR-109 (30), JBIR-110 (31), and JBIR-111 (32) (Figure 2) were purified together with trichostatin A (S6) and trichostatic acid (S7) from Streptomyces sp. RM72 is associated with an unidentified marine sponge collected near Takara Island, Japan.…”

Section: Alkaloidsmentioning

confidence: 99%

“…The compounds 30-32 have relatively weak inhibitory effects on histone deacetylase with IC 50 of 48 µg/mL, 74 µg/mL, and 57 µg/mL, respectively [9,30]. In addition, a new metabolite JBIR-107 (S8) was produced by spongederived Streptomyces tateyamensis NBRC 105047 in 2013 [31]. Four glutarimide-derived compounds (33 and S9-S11) were purified from Streptomyces anulatus S71 cultivated from a marine sponge Aplysina aerophoba collected at the Yongxing Island in the South China Sea.…”

Section: Alkaloidsmentioning

confidence: 99%

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Natural Products from Actinomycetes Associated with Marine Organisms

Chen

Zhou

et al. 2021

Marine Drugs

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The actinomycetes have proven to be a rich source of bioactive secondary metabolites and play a critical role in the development of pharmaceutical researches. With interactions of host organisms and having special ecological status, the actinomycetes associated with marine animals, marine plants, macroalgae, cyanobacteria, and lichens have more potential to produce active metabolites acting as chemical defenses to protect the host from predators as well as microbial infection. This review focuses on 536 secondary metabolites (SMs) from actinomycetes associated with these marine organisms covering the literature to mid-2021, which will highlight the taxonomic diversity of actinomycetes and the structural classes, biological activities of SMs. Among all the actinomycetes listed, members of Streptomyces (68%), Micromonospora (6%), and Nocardiopsis (3%) are dominant producers of secondary metabolites. Additionally, alkaloids (37%), polyketides (33%), and peptides (15%) comprise the largest proportion of natural products with mostly antimicrobial activity and cytotoxicity. Furthermore, the data analysis and clinical information of SMs have been summarized in this article, suggesting that some of these actinomycetes with multiple host organisms deserve more attention to their special ecological status and genetic factors.

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Section: Alkaloidsmentioning

confidence: 99%

Section: Alkaloidsmentioning

confidence: 99%

Natural Products from Actinomycetes Associated with Marine Organisms

Chen

Zhou

et al. 2021

Marine Drugs

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“…A new compound JBIR-107 (276) (Figure 16) was isolated from the culture of Streptomyces tateyamensis NBRC105047 isolated from the marine sponge, Haliclona sp. [100].…”

Section: Family Chalinidaementioning

confidence: 99%

“…A new compound JBIR-107 (276) (Figure 16) was isolated from the culture of Streptomyces tateyamensis NBRC105047 isolated from the marine sponge, Haliclona sp. [100]. Five new isocoumarins, namely peyroisocoumarins A-D (296-299) and isocitreoisocoumarinol (300) (Figure 17) were produced by the sponge-associated fungus Peyronellaea glomerate, which was derived from a finger sponge Amphimedon sp.…”

Section: Family Chalinidaementioning

confidence: 99%

Biological and Chemical Diversity of Marine Sponge-Derived Microorganisms over the Last Two Decades from 1998 to 2017

et al. 2020

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Marine sponges are well known as rich sources of biologically natural products. Growing evidence indicates that sponges harbor a wealth of microorganisms in their bodies, which are likely to be the true producers of bioactive secondary metabolites. In order to promote the study of natural product chemistry and explore the relationship between microorganisms and their sponge hosts, in this review, we give a comprehensive overview of the structures, sources, and activities of the 774 new marine natural products from sponge-derived microorganisms described over the last two decades from 1998 to 2017.

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“…The cultivation of sponge-associated microorganisms that produce biologically active compounds is the most direct method for large-scale production of these chemicals (Hill 2004 ), and extensive cultivation approaches have been attempted by groups targeting bioactive compounds (Burja et al 1999 ; Sponga et al 1999 ; Höller et al 2000 ; Jensen and Fenical 2000 ; Webster and Hill 2001 ; Burja and Hill 2001 ; Hentschel et al 2001 ; Hill 2004 ; Selvin et al 2004 ; Gunasekera et al 2005 ; Montalvo et al 2005 ; Dieckmann et al 2005 ; Sfanos et al 2005 ; Kim et al 2006 ; Kennedy et al 2009 ; Sipkema et al 2011 ; Hosoya et al 2012 ; Yamazaki et al 2012 ; Graça et al 2013 ; Izumikawa et al 2013 ; Dashti et al 2014 ; Pandey et al 2014 ; Steinert et al 2014 ). Although several researchers have reported improved cultivation of sponge-associated microorganisms using methods such as supplementing the media with sponge tissue extracts (Webster et al 2001 ), catalase, and sodium pyruvate (Olson et al 2000 ), only a minor fraction of the total sponge-associated microbial community was amenable to cultivation on laboratory media (Santavy et al 1990 ; Burja et al 1999 ; Webster and Hill 2001 ; Friedrich et al 2001 ; Hill 2004 ).…”

Section: Introductionmentioning

confidence: 99%

Electrical Retrieval of Living Microorganisms from Cryopreserved Marine Sponges Using a Potential-Controlled Electrode

et al. 2015

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The purpose of this study was to develop a novel electrical retrieval method (ER method) for living sponge-associated microorganisms from marine sponges frozen at −80 °C. A −0.3-V vs. Ag/AgCl constant potential applied for 2 h at 9 °C induced the attachment of the sponge-associated microorganisms to an indium tin oxide/glass (ITO) or a gallium-doped zinc oxide/glass (GZO) working electrode. The electrically attached microorganisms from homogenized Spirastrella insignis tissues had intact cell membranes and showed intracellular dehydrogenase activity. Dead microorganisms were not attracted to the electrode when the homogenized tissues were autoclaved for 15 min at 121 °C before use. The electrically attached microorganisms included cultivable microorganisms retrieved after detachment from the electrode by application of a 9-MHz sine-wave potential. Using the ER method, we obtained 32 phyla and 72 classes of bacteria and 3 archaea of Crenarchaeota thermoprotei, Marine Group I, and Thaumarchaeota incertae sedis from marine sponges S. insignis and Callyspongia confoederata. Employment of the ER method for extraction and purification of the living microorganisms holds potential of single-cell cultivation for genome, transcriptome, proteome, and metabolome analyses of bioactive compounds producing sponge-associated microorganisms.

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JBIR-107, a New Metabolite from the Marine-Sponge-Derived Actinomycete,Streptomyces tateyamensisNBRC 105047

Cited by 8 publications

References 11 publications

Natural Products from Actinomycetes Associated with Marine Organisms

Natural Products from Actinomycetes Associated with Marine Organisms

Biological and Chemical Diversity of Marine Sponge-Derived Microorganisms over the Last Two Decades from 1998 to 2017

Electrical Retrieval of Living Microorganisms from Cryopreserved Marine Sponges Using a Potential-Controlled Electrode

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