Long-Term Control of Refractory Hemorrhagic Radiation Proctitis With Ozone Therapy

Clavo, Bernardino; Ceballos, Daniel; Gutierrez, Dominga; Rovira, Gloria; Suárez, Gerardo; Mora, Laura; Pinar, B.; Cabezón, A.; Morales, Victoria; Oliva, Elena; Fiuza, Dolores; Santana‐Rodríguez, Norberto

doi:10.1016/j.jpainsymman.2012.06.017

Cited by 25 publications

(27 citation statements)

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“…29,[34][35][36][37][38][39] For example, ozone has been employed as a powerful drinking-water disinfectant and oxidant. 34,35,40 On the other hand, when the ozone level in an atmosphere exceeds a certain threshold value, the exposure to this gas becomes hazardous to human health and can cause serious health problems (e.g.…”

Section: -28mentioning

confidence: 99%

A novel ozone gas sensor based on one-dimensional (1D) α-Ag₂WO₄ nanostructures

et al. 2014

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aThis paper reports on a new ozone gas sensor based on a-Ag 2 WO 4 nanorod-like structures. Electrical resistance measurements proved the efficiency of a-Ag 2 WO 4 nanorods, which rendered good sensitivity even for a low ozone concentration (80 ppb), a fast response and a short recovery time at 300 C, demonstrating great potential for a variety of applications.Metal semiconducting oxides have drawn the interest of many researchers due to their wide range of applications, especially as gas sensing materials. 1-5 Among them, one-dimensional (1-D) semiconductor nanostructures have been proposed as very interesting materials, especially as gas sensor devices.6-12 It is well known that several technological applications of nanostructured materials are directly related to the morphology, particle size, crystalline phase and activity of specic crystalline planes strictly dependent on synthesis methods. 4,[13][14][15] In particular, the relationship between morphology and gas sensing properties has been well established. 4,16,17Tungsten-based oxides are an important class of materials that display wide potential functional properties, 18-20 speci-cally the silver tungstate (Ag 2 WO 4 ) compound, which can exhibit three different structures: a-orthorhombic, b-hexagonal, and g-cubic.21-25 Recently, our research group reported a detailed study of the synthesis, structural and optical properties of hexagonal nanorod-like elongated a-Ag 2 WO 4 nanocrystals obtained by different methods. 26-28Ozone (O 3 ) is an oxidizing gas used in many technological applications in different areas, such as the food industry, drinking-water treatment, medicine, microelectronic cleaning processes, and others.29,34-39 For example, ozone has been employed as a powerful drinking-water disinfectant and oxidant. 34,35,40 On the other hand, when the ozone level in an atmosphere exceeds a certain threshold value, the exposure to this gas becomes hazardous to human health and can cause serious health problems (e.g. headache, burning eyes, respiratory irritation and lung damage).34,41 The European Guidelines (2002/3/EG) recommend avoiding exposure to ozone levels above 120 ppb.41 Such arguments support the requirement for the determination and continuous monitoring of ozone levels. 3,29,41Gas sensing properties are evaluated in terms of operating temperature, sensitivity, response time, recovery time and stability.29-33 SnO 2 , In 2 O 3 and WO 3 compounds have been considered the most promising ozone gas sensors. 29-33To the best of our knowledge, to date the gas sensing properties of a-Ag 2 WO 4 nanocrystals have never been evaluated.Here, we report the sensing properties of 1-D a-Ag 2 WO 4 nanorod-like structures obtained by the microwave-assisted hydrothermal (MAH) method.42-46 Because of such properties, nanorods are potential candidates for practical applications as ozone gas sensors.The crystalline phase of the as-obtained a-Ag 2 WO 4 sample was analyzed by X-ray diffraction measurement and all reec-tions were indexed to an orthorhombic struc...

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Section: -28mentioning

confidence: 99%

A novel ozone gas sensor based on one-dimensional (1D) α-Ag₂WO₄ nanostructures

et al. 2014

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“…However, data on the use of ozone or ozonated oils in radiation proctitis are limited. Recently, Clavo et al (26) reported the beneficial effects of ozone therapy on refractory haemorrhagic radiation proctitis. In the study, 17 patients received an ozone gas mixture via rectal insufflations and topical application of ozonised oil, and were followed up for a median of 40 months (3-56 months).…”

Section: Discussionmentioning

confidence: 99%

“…In the study, 17 patients received an ozone gas mixture via rectal insufflations and topical application of ozonised oil, and were followed up for a median of 40 months (3-56 months). Clavo et al (26) concluded that ozone treatment improved the clinical symptoms of haemorrhagic radiation proctitis. However, this is the only study published in the English- language literature, and to date, no studies have reported the effects of OzOO on histopathological findings of ARP in animals or in humans.…”

Section: Discussionmentioning

confidence: 99%

“…Thus, OzOO was confirmed to have beneficial effects on ARP. Ozone was chosen for its demonstrated benefits in radiation-induced cystitis (23), refractory haemorrhagic radiation proctitis (26), and ileal injury (25). Calvo et al (23) reported that ozonated bi-distilled water could be administered intravesicularly to prevent haematuria caused by radiation-induced cystitis.…”

Section: Discussionmentioning

confidence: 99%

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Effects of Ozonated Olive Oil on Acute Radiation Proctitis in Rats

Gültekin¹,

Bakkal²,

Sümer³

et al. 2013

Balkan Med J

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“…Ozone (O 3 ) is an oxidizing gas which exhibits industrial applications such as drinking-water treatment, microelectronic cleaning processes, among others (Glaze 1987;Patil et al 2009;Bocci et al 2011;Korotcenkov and Cho 2012;Clavo et al 2013;Graham et al 2013;Simoes and Simoes 2013). The real-time monitoring of the O 3 concentration levels is essential for human health.…”

Section: Introductionmentioning

confidence: 99%

An investigation into the influence of zinc precursor on the microstructural, photoluminescence, and gas-sensing properties of ZnO nanoparticles

Catto

Silva

Bernardi³

et al. 2014

J Nanopart Res

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This paper describes the effect of different zinc precursors, acetate, oxide, and nitrate, on the structure, microstructure, photoluminescence, and ozone gas-sensing properties of zinc oxide (ZnO) nanoparticles. Transmission and scanning electron microscopy, and BET surface area show a dependence of the particle size and surface area with the precursor type. The ZnO sample synthesized from zinc nitrate shows the best photoluminescence (PL) emission. Although electron paramagnetic resonance shows in all samples the presence of a g-signal attributed to oxygen vacancies, it is not possible to correlate the presence of these defects with PL emission behavior. Furthermore, ZnO sample synthesized from zinc nitrate also shows the best ozone gas-sensing response, however, our results do not allow correlating the best PL emission in the visible region with the best sensor response to ozone gas.

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Long-Term Control of Refractory Hemorrhagic Radiation Proctitis With Ozone Therapy

Abstract: Persistent advanced HRP was significantly improved with O3T. The addition of O3T can be useful as a complementary treatment in the long-term management of HRP and, as such, merits further evaluation.

Cited by 25 publications

References 25 publications

A novel ozone gas sensor based on one-dimensional (1D) α-Ag₂WO₄ nanostructures

A novel ozone gas sensor based on one-dimensional (1D) α-Ag₂WO₄ nanostructures

Effects of Ozonated Olive Oil on Acute Radiation Proctitis in Rats

An investigation into the influence of zinc precursor on the microstructural, photoluminescence, and gas-sensing properties of ZnO nanoparticles

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Long-Term Control of Refractory Hemorrhagic Radiation Proctitis With Ozone Therapy

Abstract: Persistent advanced HRP was significantly improved with O3T. The addition of O3T can be useful as a complementary treatment in the long-term management of HRP and, as such, merits further evaluation.

Cited by 25 publications

References 25 publications

A novel ozone gas sensor based on one-dimensional (1D) α-Ag2WO4 nanostructures

A novel ozone gas sensor based on one-dimensional (1D) α-Ag2WO4 nanostructures

Effects of Ozonated Olive Oil on Acute Radiation Proctitis in Rats

An investigation into the influence of zinc precursor on the microstructural, photoluminescence, and gas-sensing properties of ZnO nanoparticles

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Product

Resources

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A novel ozone gas sensor based on one-dimensional (1D) α-Ag₂WO₄ nanostructures

A novel ozone gas sensor based on one-dimensional (1D) α-Ag₂WO₄ nanostructures