21β-Hydroxy-oleanane-type triterpenes from Hippocratea excelsa

Comparative fingerprint analyses of extracts from the root bark of wildHippocratea excelsaand “Cancerina” by high-performance liquid chromatography

“…Similar results have been reported when using a partition of more polar solvents, such as ethanol, with n-hexane or resuspension in n-hexane [11][12][13]. Some authors have reported the extraction of these compounds with a mixture of n-hexane (e.g., ethyl ether (1:1, v/v) or only n-hexane) [5,6]; however, such extractions are performed through exhaustive maceration or with a Soxhlet apparatus.…”

“…Sesquiterpene alkaloids have been isolated from the root bark of specimens acquired in the “Mercado de Sonora” (Mexico City) ; however, studies on wild H. excelsa from Yucatan, Mexico have not reported such compounds. From this wild species, pentacyclic triterpenes, such as oleans and friedelans, have been isolated , including a new triterpene named dzununcanona in honor of the location where the sample was collected (Dzununcán, Merida, Mexico) . These differences between the metabolites isolated from the commercial cancerina root bark and the wild H. excelsa have raised the question of whether the cancerina root is H. excelsa .…”

Ficus deltoideaextract down-regulates protein tyrosine phosphatase 1B expression in a rat model of type 2 diabetes mellitus: a new insight into its antidiabetic mechanism

“…Seven compounds were isolated from the 70 % ethanolic extract of FD leaves. Four of them are known compounds, which are lupeol (F1), (24E)-stigmasta-5,8-dien-3β-ol (F2), vitexin (apigenin-8C-β-D-glucoside) (F6) and isovitexin (apigenin-6C-β-D-glucoside) (F7) (46)(47)(48)(49)(50)(51)(52)(53)(54) . Two newly isolated compounds, gallic acid (F4) and chryseriol-7O-α-rhamnoside (F5), were obtained.…”

New ursane triterpenoids from Ficus pandurata and their binding affinity for human cannabinoid and opioid receptors

“…The known compounds were identified by analysing the spectroscopic data (1D and 2D NMR) and comparing their data with those in the literature to be α -amyrin acetate ( 1 ) (Virgilio et al 2015), α -amyrin ( 2 ) (Virgilio et al 2015), 3 β -acetoxy-20-taraxasten-22-one ( 3 ) (Ramadan et al 2009; Ahmed 2010), 3 β -acetoxy-11 α -methoxy-olean-12-ene ( 4 ) (Kuo and Chiang 2000; Mallavadhani et al 2006; Barbosa et al 2010), 3 β -acetoxy-11 α -methoxy-12-ursene ( 5 ) (Mathias et al 2000; Barbosa et al 2010), 11-oxo- α -amyrin acetate ( 6 ) (Fingolo et al 2013), 11-oxo- β -amyrin acetate ( 7 ) (Fingolo et al 2013), palmitic acid ( 8 ) (Ajoku et al 2015), stigmast-4,22-diene-3,6-dione ( 9 ) (Itokawa et al 1973), stigmast-4-ene-3,6-dione ( 10 ), stigmasterol ( 12 ) (Mohamed and Ibrahim 2007; Kamboj and Salujai 2011; Chaturvedula and Prakash 2012), β -sitosterol ( 13 ) (Al-Musayeib et al 2013), stigmast-22-ene-3,6-dione ( 14 ) (Wei et al 2004), stigmastane-3,6-dione ( 15 ) (Wei et al 2004; Lim et al 2005), 3 β ,21 β -dihydroxy-11 α -methoxy-olean-12-ene ( 16 ) (Cáceres-Castillo et al 2008), 3 β -hydroxy-11 α -methoxyurs-12-ene ( 18 ) (Fujita et al 2000), 6-hydroxystigmast-4,22-diene-3-one ( 19 ) (Kontiza et al 2006; Georges et al 2006), 6-hydroxystigmast-4-ene-3-one ( 20 ) (Kontiza et al 2006; Georges et al 2006) and β -sitosterol-3- O - β -D-glucopyranoside ( 22 ) (Khatun et al 2012). …”