2022 Taiwan clinical multicenter expert consensus and recommendations for thyroid radiofrequency ablation

Wang, Lin; Chen, WenChieh; Wang, Pei‐Wen; Chan, Yi‐Chia; Chang, Yen‐Hsiang; Chen, Harn-Shen; Chen, Szu-Tah; Chen, Wei-Chih; Cheng, Kai-Lun; Chi, Shun‐Yu; Chiang, Pi-Ling; Chou, Chen‐Kai; Chou, Feng-Fu; Huang, Shun‐Chen; Liu, Feng-Hsuan; Luo, Sheng‐Dean; Tseng, Fen‐Yu; Wang, Chih‐Yuan; Wang, Wen‐Hung; Wu, Mei‐Hwan

doi:10.14366/usg.22126

Ultrasonography

2023

DOI: 10.14366/usg.22126

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2022 Taiwan clinical multicenter expert consensus and recommendations for thyroid radiofrequency ablation

Lin Wang¹,

WenChieh Chen²,

Pei‐Wen Wang³

et al.

Abstract: Radiofrequency ablation (RFA) is a minimally invasive management strategy which has been widely applied on thyroid benign and recurrent malignant lesions as an alternative to surgery in Taiwan. Experts from the academies associated with interventional radiology, endocrinology, and endocrine surgeons collaborated to develop the first consensus regarding thyroid RFA in Taiwan.The modified Delphi method was used to reach a consensus. By comprehensive review of recent and valuable literature and expert opinions, t… Show more

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Cited by 5 publications

References 186 publications

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Highly Efficient Production of Desired Solid Forms of Drugs with Improved Mechanical Properties via an Organic Solvent-Free Sublimation Process

Zhao

Liu

et al. 2023

ACS Sustainable Chem. Eng.

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The pharmaceutical industry is required to constantly broaden its development areas and accelerate technical transformation because of the continued global rise in medicine consumption. However, the usage of organic solvents in pharmaceutical production results in up to 20 million tons annually of chemical waste, causing a serious environmental problem. Here, we proposed a solvent-free sustainable chemical technology, sublimation crystallization, for highly efficient screening and preparation of pharmaceutical solid forms (i.e., polymorphs), which eliminates the wastes associated with solvent use from the source. By adjusting the parameters of sublimation crystallization, we have obtained multiple polymorphs of several important drugs, including the antituberculosis drug pyrazinamide (PZA) and nonsteroidal anti-inflammatory drugs (NSAIDs), flufenamic acid (FFA) and mefenamic acid, particularly γ form of PZA and polymorphs IV and VII of FFA, which are difficult to produce from conventional solution crystallization methods. Mechanical property measurements from both powder and single crystal tests reveal that the γ form of PZA readily prepared by sublimation crystallization has the most excellent tabletability properties. In situ crystal growth observations indicate a direct vapor-to-crystal growth mechanism for the sublimation crystallization process consistent with conventional vapor phase deposition. Furthermore, the governing factors and growth mechanisms of sublimation and solution crystallization processes were analyzed and discussed, and it was found that the rate-limiting step of crystal growth is the surface-integration process in solution crystallization, whereas it becomes the surface diffusion process in sublimation crystallization. Overall, our developed sublimation crystallization provides a promising green technology for the development and production of (new) drugs, broadening the thinking behind the development of sustainable chemicals.

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Highly Efficient Production of Desired Solid Forms of Drugs with Improved Mechanical Properties via an Organic Solvent-Free Sublimation Process

Zhao

Liu

et al. 2023

ACS Sustainable Chem. Eng.

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show abstract

Sonographic Evolution and Pathologic Findings of Papillary Thyroid Cancer After Radiofrequency Ablation: A Five-Year Retrospective Cohort Study

Li,

Yan

et al. 2024

Thyroid®

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Identifying income heterogeneity determinants using the method of moments quantile regression

Ha¹

2023

Asian-Pac Economic Lit

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Prior studies have typically concentrated on poverty status to determine anti‐poverty measures; however, this approach cannot sufficiently detect income heterogeneity. This study employs quantile regression for panel data to investigate the Korean Labour and Income Panel Study 2003–2020. Moreover, it adopts both household‐ and community‐level variables and separates demographic groups as working‐age and older adults, considering Korea's severe old‐age poverty. The findings indicate that household‐level characteristics, such as householder's gender, physical health, and employment status, present heterogeneous effects across the income distribution. Second, low‐income households are more vulnerable to regional economic and labour market downturns than high‐income neighbours. Lastly, although the National Pension, a backbone of the public pension system, provides limited supports for retirees because it was introduced much later than other countries, it assists low‐income old adults more effectively. Therefore, this study suggests more tailored redistribution measures, considering heterogeneous effects of household‐ and community‐level environments, and a further expansion of the National Pension to mitigate old‐age poverty.

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2022 Taiwan clinical multicenter expert consensus and recommendations for thyroid radiofrequency ablation

Cited by 5 publications

References 186 publications

Highly Efficient Production of Desired Solid Forms of Drugs with Improved Mechanical Properties via an Organic Solvent-Free Sublimation Process

Highly Efficient Production of Desired Solid Forms of Drugs with Improved Mechanical Properties via an Organic Solvent-Free Sublimation Process

Sonographic Evolution and Pathologic Findings of Papillary Thyroid Cancer After Radiofrequency Ablation: A Five-Year Retrospective Cohort Study

Identifying income heterogeneity determinants using the method of moments quantile regression

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