2018
DOI: 10.5489/cuaj.5255
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2018 Canadian Urological Association guideline for Peyronie's disease and congenital penile curvature

Abstract: Peyronie’s disease (PD) is a highly prevalent condition that affects the physical and psychosocial well-being and quality of life (QoL) for thousands of Canadian men. The specific etiology of PD remains poorly understood and there remains a paucity of randomized placebo-controlled trials evaluating treatment interventions.1-3 PD can be found in up to 8.9% of men, a remarkable increase in cited prevalence that is attributable to growing awareness (as historical data suggested a rate of less than 1%); the burden… Show more

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Cited by 54 publications
(51 citation statements)
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“…There is no strong evidence to date that supports the use of oral monotherapy for PD. The AUA and CUA guidelines on PD recommend against oral therapy with vitamin E, tamoxifen, omega‐3‐fatty acids, procarbazine and vitamin E/L‐carnitine combination 12,36 . Non‐steroidal anti‐inflammatories are indicated for penile pain, particularly in the early phase 12 .…”
Section: Non‐invasive Therapymentioning
confidence: 99%
“…There is no strong evidence to date that supports the use of oral monotherapy for PD. The AUA and CUA guidelines on PD recommend against oral therapy with vitamin E, tamoxifen, omega‐3‐fatty acids, procarbazine and vitamin E/L‐carnitine combination 12,36 . Non‐steroidal anti‐inflammatories are indicated for penile pain, particularly in the early phase 12 .…”
Section: Non‐invasive Therapymentioning
confidence: 99%
“…Erectile dysfunction (ED) is the recurrent and persistent inability to achieve and/or maintain an erection adequate to permit sexual performance for at least three months. 10 ED affects more than 50% of men between the ages of 40 and 70 years and rates rise over 70% for patients above 70. 11 Serious conditions to screen for: Peyronie's disease (PD), cardiovascular disease, neurologic disorders, unstable mental health.…”
Section: Erectile Dysfunction (Authors: Dr Jeffrey Campbell Dr Germentioning
confidence: 99%
“…Suggested investigations: Sexual Health Inventory for Men (SHIM)/International Index of Erectile Function (IIEF) questionnaire, fasting glucose or hemoglobin A1C, lipid profile, testosterone and hormone profile (if warranted). 10 Treatment: Identifying reversible causes and suggesting lifestyle modifications (smoking cessation, medication changes, exercise, etc.) should be considered first.…”
Section: Clinical Pearls To Managing Men's Health Conditions During Tmentioning
confidence: 99%
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