2. Human Risk Assessment of Heavy Metals: Principles and Applications

Dorne, Jean-Lou C.M.; Kass, George E.N.; Bordajandi, Luisa R.; Amzal, Billy; Bertelsen, Ulla; Castoldi, Anna Federica; Heppner, Claudia; Eskola, Mari; Fabiansson, Stefan; Ferrari, P; Scaravelli, Elena; Dogliotti, Eugenia; Fuerst, Peter G.; Boobis, Alan R.; Verger, P

doi:10.1039/9781849732116-00027

Cited by 51 publications

(38 citation statements)

References 3 publications

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“…Some trace metals and metalloids, such as As, Cd and Pb, are included in the list of potentially harmful substances (Dorne et al, 2011). Their accumulation in organs after a continued consumption of foodstuff relatively rich in these elements may lead to important dysfunctions and diseases (Flora, 2009).…”

Section: Introductionmentioning

confidence: 99%

Metals and metalloids in fruits of tomatoes (Solanum lycopersicum) and their cultivation soils in the Basque Country: Concentrations and accumulation trends

Rodriguez-Iruretagoiena

Trebolazabala

Martínez‐Arkarazo

et al. 2015

Food Chemistry

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Section: Introductionmentioning

confidence: 99%

Metals and metalloids in fruits of tomatoes (Solanum lycopersicum) and their cultivation soils in the Basque Country: Concentrations and accumulation trends

Rodriguez-Iruretagoiena

Trebolazabala

Martínez‐Arkarazo

et al. 2015

Food Chemistry

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“…The HQ (ingestion and dermal contact) and HI for non-carcinogenic risk of some trace metals in drinking water have been calculated using equations (7), (8), and (9). If the HQ exceeds 1, there might be a concern for non-carcinogenic effects.…”

Section: Hazard Quotient (Hq) and Hazard Index (Hi)mentioning

confidence: 99%

“…In recent years, heavy metal toxicity has increased as a serious concern all over the world, as these metals are indestructible and most of them have toxic effects on living organisms, when they exceed a certain concentration [1][2][3]; [4,5]; [6]. Heavy metals are ubiquitous in the environment [7][8][9]. Additionally, man-made pollution sources such as mining, metal smelting and processing, industrial wastewater, fossil fuels burning, application of fertilizer, pesticides, and household garbage can play a significant role towards a high level of heavy metal in water body [6].…”

Section: Introductionmentioning

confidence: 99%

Seasonal Variation And Preliminary Risk Assessment Of Trace Element Pollution In Surface Water From Langat River, Malaysia

Alam

Mokhtar

Alam

et al. 2019

Preprint

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Heavy metals are widely used in various industries and became a great concern all over the world due to environmental contamination. This study provides an assessment of seasonal variability and risks to human health associated with the exposure to heavy metals concentrated in Langat river water of Malaysia. The Department of Environment (DOE) Malaysia kindly provided the heavy metal concentration data in water for this study. Several multivariate estimation such as an independent t test, box-and-whisker plot and Principal component analysis were carried out to evaluate the seasonal variation of metals concentration in water. The average value of ten analyzed metals was 250.81 µg/l and followed in order of abundance by August > Jun > February > October > April > December > March > May > September > January > July > November. The calculated HPI was 123.42, which is far above the critical index value of 100, indicating pollution with respect to heavy metals. Estimates of health risks associated with river water were summarized according to non-carcinogenic and carcinogenic health effects. No potential threat was detected for noncarcinogenic risk as the HI values calculated were <1. Potential carcinogenic risks associated with the ingestion and dermal absorption of heavy metals in water were evaluated probabilistically by performing 10,000 trails for Monte Carlo simulation where potential carcinogenic risk exists in case of Cd and As.It is necessary to take proper steps to reduce the pollution of heavy metals in Langat River.

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“…The basic elements of risk assessment of chemical hazards include four steps: hazard identification, hazard characterization, exposure estimation and risk characterization. The risk assessment method for chemical contaminants is defined by WHO (World Health Organization), US EPA (Environmental Protection Agency) and EFSA (European Food Safety Authority) (Dorne et al, 2011).…”

Section: Introductionmentioning

confidence: 99%

Human health risk assessment of lead in nectarines

Šukalić¹,

Ahmetović²,

Mačkić³

et al. 2018

Acta agriculturae Serbica

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The aim of the paper was to determine the level of soil contamination with lead and perform risk assessment by calculating the Hazard Quotient Index (HQI). The research was carried out during 2015 and 2016 at three locations in Herzegovina (Mostar, Čapljina, and Stolac), where nectarine cultivars ('Big Top' and 'Caldesi 2000') were cultivated. At the Mostar and Čapljina locations, the total content of lead in the soil exceeded MPC values in both years of research. Estimated daily intake (EDI) and estimated weekly intake (EWI) values of lead in the studied nectarine varieties showed no acute or chronic risk for human health.

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2. Human Risk Assessment of Heavy Metals: Principles and Applications

Cited by 51 publications

References 3 publications

Metals and metalloids in fruits of tomatoes (Solanum lycopersicum) and their cultivation soils in the Basque Country: Concentrations and accumulation trends

Metals and metalloids in fruits of tomatoes (Solanum lycopersicum) and their cultivation soils in the Basque Country: Concentrations and accumulation trends

Seasonal Variation And Preliminary Risk Assessment Of Trace Element Pollution In Surface Water From Langat River, Malaysia

Human health risk assessment of lead in nectarines

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