2,4,6-Trijod-3-acetaminobenzoes�ure-Abk�mmlinge als Kontrastmittel

The choleretic effect of iodipamide.

“…Calculation of the slope of the least squares line of the relation between bile flow and iodipamide excretion for all six studies indicates that 22 ml of additional bile are formed for each millimole of iodipamide excreted in the bile. 8 Chromotographically pure, Calbiochem, San Diego, Calif. 'Loeb, P. M., R. N. Berk, G. K. Feld, and H. 0.…”

“…Hoenig and Preisig showed in dogs that the choleresis due to bromosulfophthalein, ioglycamide, and taurocholate per millimole of compound excreted was 9.2, 11.9, and 7.3 ml, respectively (7). As early as 1953 Langecker, Harwart, and Junkmann noted increased bile flow associated with the biliary excretion of iodipamide in the rat and dog (8). Sperber and Sperber, using data from Fischer's studies in dogs (10), determined that the excretion of 1 mmol of iodipamide resulted in the production of about 35 ml of bile (17).…”

“…A so-called bile salt-independent bile fraction of canalicular origin has been identified which is probably dependent on the stimulation of inorganic ion transport across the canalicular membrane (4)(5)(6). The choleresis induced by most exogenous organic anions seems to be related to their osmotic activity as they are secreted into bile (7,8). This osmotic activity in bile is markedly influenced by the ability of the anions to interact with bile salt micelles or to form molecular aggregates themselves (9).…”

On the Visualization of the Renal Pelves in Cholegraphy

“…The opinion has since been expressed by various workers in this field that cholegraphic visualization of the urinary system may be suggestive of hepato-biliary disease (NISSEN arid HORSTMANNSHOFF 1953, GERSHON-COHEN et coll. 1954, NEMOURS-AUGUSTE and BARAG 1954, RUCKENSTEINER 1954, BERK et coll. 1955.…”

On the Visualization of the Renal Pelves in Cholegraphy

“…The opinion has since been expressed by various workers in this field that cholegraphic visualization of the urinary system may be suggestive of hepato-biliary disease (NISSEN and HORSTMANNSHOFF 1953, GERSHON-COHEN et coll. 1954, NEMouRs-AUGUSTE and BARAG 1954, RUCKENSTEINER 1954, BERK et coll, 1955. The renal pelves have, however, been visualized in cholegrams of apparently healthy persons (SENEQUE 1954) and the author has described one case, in which at repeated cholegraphy no contrast substance could be demonstrated in the renal pelves of a patient with atresia of the hepatic ducts.…”