2,4,6-Trichloro-1,3,5-triazine catalyzed synthesis of thiiranes from oxiranes under solvent-free and mild conditions

A facile and Convenient Method for Synthesis of Thiiranes under Mild Condition Using Phase Transfer Catalyst

“…All products were characterized by 1 H NMR, 13 C NMR, IR and by comparison with authentic samples 6,9,16-18 . The IR spectra were recorded on Bomem FT-IR spectrometer.…”

“…4 Other reagents such as phosphine sulfide, 5 methylbenzothiazol-2-thione, 6 and dimethylthio formamide 7 have been reported to produce thiiranes from oxiranes. Usually with these sulfurating agents, several different Lewis acids such as RuCl 3 12 and cyanuric chloride 13 have been used for the conversion of oxiranes to thiiranes. However many of these methods suffer from using strongly acidic or oxidizing conditions, undesirable side reactions, long reaction time, high temperature, use of organic solvents and desulfuration of the resulting thiirane to the olefin.…”

Synthesis of β-amino alcohols by ring opening of epoxides with amines catalyzed by cyanuric chloride under mild and solvent-free conditions

“…Recent results from our laboratory had shown that simple and readily available cyanuric chloride can assist some important organic reactions (33,34). In continuation to our ongoing program, we would like to report a mild, practical, and efficient method for the opening of epoxides with substituted amines using catalytic amounts of cyanuric chloride under solvent-free conditions (Scheme 1).…”

Three‐Membered Heterocycles. Structure and Reactivity

“…product [688]. Magnesium hydrogen sulfate has also proven to be an effective activating agent [689].…”