2-(3-Oxo-1,3-dihydroisobenzofuran-1-yl)phthalazin-1(2H)-one

Abstract

The reaction of 2-carboxy­benzaldehyde and hydrazine hydrate unexpectedly yielded the title compound, C16H10N2O3, which comprises one phthalide ring, one phthalazine system and a chiral centre. The phthalide unit is almost perpendicular to the phthalazine system, forming a dihedral angle of 87.1 (3)°. The packing is governed by weak C—H⋯O hydrogen-bonding inter­actions, forming layers parallel to the ab plane.

Ultrasensitive fluorescence detection of nitro-explosives by dihydro-oxoisobenzofuranyl-phthalazinone obtained from the Cd(ii)-catalyzed cyclization of azinodimethylidyne-benzoic acid

“…1 and Table S1, ESI†). As the crystal structure of 1 is already known, 36 the cell parameters obtained from our analysis were compared with that of the reported ones, which corroborate well and thus a more detailed description is omitted here. Further, powder X-ray diffraction (PXRD) analyses of 1 were also performed and compared with its simulated PXRD pattern, showing its structural identity both in the crystalline and amorphous forms (Fig.…”