1D-4 High Speed Imaging of Bubble Clouds in Pulsed Cavitational Ultrasound Therapy - Histotripsy

Mechanisms of nuclei growth in ultrasound bubble nucleation

“…On the other hand, small values of at intrinsic histotripsy pressure–temperature pairs suggests that no significant heat transport takes place into the nuclei, and these are free to nucleate in higher quantities. Again, this correlates with documented experimental results, which report the appearance of densely populated clouds of bubbles for intrinsic threshold histotripsy [11] , [63] , [64] .…”

Enhanced thrombolytic effect induced by acoustic cavitation generated from nitrogen-doped annealed nanodiamond particles

“…In the field of biomedical research, ultrasonic cavitation has demonstrated its significance in various applications of high-intensity focused ultrasound (HIFU) therapy. These include tumor treatment [1] , [2] , [3] , lithotripsy [4] , histotripsy [5] , [6] , thrombolysis [7] , [8] , [9] , blood–brain barrier disruption [10] , [11] and drug delivery [12] , [13] . The dynamics of cavitation in response to ultrasound excitation can be classified into two types, namely stable cavitation (SC) and inertial cavitation (IC) [14] .…”

Ultrasound imaging and beyond: recent advances in medical ultrasound

“…Although BBB opening is caught attention from general public, ultrasound mediated drug delivery has also been widely researched for the targeted cancer treatment in both body and brain. The last noteworthy ultrasound therapy is histotripsy [13]. This term is antonym to lithotripsy which indicates destruction of calcified targets such as kidney stone.…”