2014
DOI: 10.1016/j.ejps.2014.08.002
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18FDG a PET tumor diagnostic tracer is not a substrate of the ABC transporter P-glycoprotein

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Cited by 8 publications
(10 citation statements)
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“…Altogether, these results confirm that 18 F-FDG is not transported by P-gp (25). Phosphorylation of 18 F-FDG by HK, as well as P-gp-mediated transport, may competitively modulate D-glucose and intracellular ATP concentration.…”
Section: Discussionsupporting
confidence: 73%
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“…Altogether, these results confirm that 18 F-FDG is not transported by P-gp (25). Phosphorylation of 18 F-FDG by HK, as well as P-gp-mediated transport, may competitively modulate D-glucose and intracellular ATP concentration.…”
Section: Discussionsupporting
confidence: 73%
“…1). This time-dependent shift was also found in cancer cells (17,25). Interestingly, CsA was previously shown to abolish the difference in 18 F-FDG uptake between MDRpositive and MDR-negative cell lines (23).…”
Section: Discussionsupporting
confidence: 64%
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