2015
DOI: 10.1016/j.ejps.2015.03.026
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2′[18F]-fluoroethylrhodamine B is a promising radiotracer to measure P-glycoprotein function

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Cited by 5 publications
(5 citation statements)
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“…Membrane fraction of NIH 3T3 mouse fibroblast cells expressing wild-type, E556M and quadruple mutant ABCB1 and their ABCB1-negative counterpart was prepared according to Sarkadi et al [56] with minor modifications previously described in [98]. Cells were harvested by scraping them into ice-cold PBS and washed twice at 300 × g for 5 min.…”
Section: Preparation Of Membranesmentioning
confidence: 99%
“…Membrane fraction of NIH 3T3 mouse fibroblast cells expressing wild-type, E556M and quadruple mutant ABCB1 and their ABCB1-negative counterpart was prepared according to Sarkadi et al [56] with minor modifications previously described in [98]. Cells were harvested by scraping them into ice-cold PBS and washed twice at 300 × g for 5 min.…”
Section: Preparation Of Membranesmentioning
confidence: 99%
“…It was reported that the MDR had positive expression in MDA-MB-231 and MCF-7 breast cancer cells [ 25 ]. Because some cations are the substrate for MDR protein, cationic radiotracers have been clinically used for noninvasive monitoring of the multidrug resistance transport function in tumors [ 26 , 27 ]. Lissamine Rhodamine B (LRB) is a member of rhodamine derivatives, which is also the substrate for MDR protein.…”
Section: Discussionmentioning
confidence: 99%
“…A description of the design of the fluoride-drying module is illustrated below: 6). [20][21][22][23] As a base for the module, a 2 mm thick aluminum plate was used, which is partially reinforced on the outside with aluminum profiles. The framework and nonelectronic components of the control unit were 3D printed (Figure 4).…”
Section: Automated 18 F-drying Modulementioning
confidence: 99%
“…Fluoroalkylation examples of different PET‐Tracer, 19 2‐[ 18 F]fluoroethyl harmol as monoamino oxidase tracer ( 3 ), 2′[ 18 F]‐fluoroethylrhodamine B as P‐glycoprotein tracer ( 4 ), [ 18 F]FP‐TZTP as muscarinic tracer ( 5 ), [ 18 F]FE‐β‐CIT as dopamine transport tracer ( 6 ) 20–23 …”
Section: Introductionmentioning
confidence: 99%