18-Year-Old Woman with an Embryonal Rhabdomyosarcoma of the Uterus in Statu Nascendi

Strahl, Olga; Hartmann, Arndt; Thiel, Falk; Beckmann, Matthias W.; Lux, Michael P.

doi:10.1055/s-0032-1328076

Cited by 8 publications

(8 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Genital and Gynecologic tumors in children are rare and represent less than 5% of all pediatric neoplasms [1]. Vaginal parts of these tumors can have a spectrum and variable clinical presentation, including abdominal pain, abdominal mass, chronic genital ulcer, bloody discharge or tissue protruding from the vaginal orifice [2].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Vaginal Parts of Sarcoma Botryoides in Children: A Case Report

Aboud¹

2019

Act Scie Paedia

View full text Add to dashboard Cite

Introduction: Genital and Gynecologic tumors in children are rare and represent less than 5% of all pediatric neoplasms. Vaginal parts of these tumors can have a spectrum and variable clinical presentation. Rhabdomyosarcoma (RMS) is considered the most common soft-tissue sarcoma found in children. We present a case of Sarcoma botryoides to illustrate the difficulties encountered by pediatric surgeons in the management of this malignant and aggressive tumor. Case Report: A 3 years old girl presented to our pediatric surgery clinic with 2-months history of a protruding mass from her vaginal orifice. The patient was arranged for surgery, where an en-bloc dissection of the total mass was done. A classic histologic findings in sarcoma botryoides were confirmed. Conclusion: All parents and concerned health workers should take care on finding a protruding mass in the genitourinary tract of their child and they should bring the child to medical attention, this can enhance the early diagnosis and better prognosis. 19. Raney RB., et al. "Rhabdomyosarcoma and undifferentiated sarcoma in the first two decades of life: a selective review of inter group rhabdomyosarcoma study group experience and rationale for Intergroup Rhabdomyosarcoma Study V".

show abstract

Section: Introductionmentioning

confidence: 99%

“…It is the most common soft tissue sarcoma in childhood and young adulthood, and account for 4-6% of all malignancies in this age group [1]. The tumors also occurs rarely in the cervix or uterine fundus and often is described in other term as "cluster of grapes" [3].…”

Section: Introductionmentioning

confidence: 99%

Vaginal Parts of Sarcoma Botryoides in Children: A Case Report

Aboud¹

2019

Act Scie Paedia

View full text Add to dashboard Cite

show abstract

“…This tumor is seen almost exclusively in infants, it is characterized by ‘grape-like’ appearance caused by polypoid mass arising in submucosal tissue [2, 4]. …”

Section: Introductionmentioning

confidence: 99%

“…They represent the most common soft tissue tumor in childhood. The head and neck region are the most affected tumor sites, followed by the genitourinary tract [ 2 ]. Four major histologic subtypes of RMS are identified, Embryonal, Alveolar, Botryoid, pleomorphic/undifferentiated [ 2 , 3 ].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Rhabdomyosarcoma of the genital tract in an 18-month-old girl

ALSaleh

ALwadie

Gari

2017

Journal of Surgical Case Reports

View full text Add to dashboard Cite

Embryonal Rhabdomyosarcoma ‘Botryoid Type’ is a rare soft tissue tumor that arises within the wall of the bladder or vagina and seen almost exclusively in infants. Treatment is combination of surgery with adjuvants chemotherapy and radiotherapy. We report a case of an 18-month-old Saudi girl presented with history of abdo-pelvic mass, bleeding per vagina and a mass protruding through the introitus. Computed tomography (CT) done reveling large heterogeneous pelvic mass arising from the uterus, biopsy of mass confirmed the diagnosis (sarcomabotryoidal). The patient received multiple cycles of combination chemotherapy as a neoadjuvant treatment then underwent total abdominal hysterectomy with upper vaginectomy. Postoperatively, the patient received more cycles of chemotherapy. CT scan for post-treatment evaluation was done and showed no evidence of local recurrence or distant metastasis. Currently, she is disease-free on remission with no complains.

show abstract