158 Umbilical cord blood-derived mesenchymal stem cells (UCB-MSC) used for the prevention of metritis in cattle

Verma, Vinod; Ghai, S.; Ansari, Shama; Saini, Sikander; Thakur, Aneesh; Kumar, Ashutosh; Kumar, Sailesh; Malakar, Dhruba

doi:10.1071/rdv34n2ab158

Cited by 1 publication

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“…Polymorphonuclear (PMN) cell count was reduced in cervical vaginal fluid and the expression of IL-6, IL-10, cathelicidin, lipocalin, cystatin and angiopoietin were observed at day 3 in the IV + local group [ 64 ]. More recently, UCB-MSCs and their EVs have also been successfully used for metritis treatment by the same research group [ 70 ]. Moreover, in this case, a higher decrease in PMN was observed for MSCs and EV-treated cows compared with antibiotic-treated ones, as well as an increase in the expression of anti-inflammatory cytokines [ 70 ].…”

Section: Bovine Mscs For Clinical Treatmentsmentioning

confidence: 99%

“…More recently, UCB-MSCs and their EVs have also been successfully used for metritis treatment by the same research group [ 70 ]. Moreover, in this case, a higher decrease in PMN was observed for MSCs and EV-treated cows compared with antibiotic-treated ones, as well as an increase in the expression of anti-inflammatory cytokines [ 70 ].…”

Section: Bovine Mscs For Clinical Treatmentsmentioning

confidence: 99%

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An Update on Applications of Cattle Mesenchymal Stromal Cells

Merlo

Gugole

Iacono

2022

Animals

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Attention on mesenchymal stromal cells (MSCs) research has increased in the last decade mainly due to the promising results about their plasticity, self-renewal, differentiation potential, immune modulatory and anti-inflammatory properties that have made stem cell therapy more clinically attractive. Furthermore, MSCs can be easily isolated and expanded to be used for autologous or allogenic therapy following the administration of either freshly isolated or previously cryopreserved cells. The scientific literature on the use of stromal cells in the treatment of several animal health conditions is currently available. Although MSCs are not as widely used for clinical treatments in cows as for companion and sport animals, they have the potential to be employed to improve productivity in the cattle industry. This review provides an update on state-of-the-art applications of bovine MSCs to clinical treatments and reproductive biotechnologies.

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Section: Bovine Mscs For Clinical Treatmentsmentioning

confidence: 99%

Section: Bovine Mscs For Clinical Treatmentsmentioning

confidence: 99%