1487 Neonatal HSV disease in infants under 90 days of age in UK and Ireland: BPSU study interim analysis

Epidemiology of herpes simplex virus type 2 in Europe: systematic review, meta-analyses, and meta-regressions

“…In the UK and Ireland during 2019–2021, incidence was estimated at 6.9 cases per 100,000 live births. 48 Overall, studies suggested an increasing trend. Of 59 reported cases in the UK during 2019–2021, 29 (49.2%) were due to HSV-1, 25 (42.4%) were due to HSV-2, and the remaining 5 (8.5%) had unknown HSV type.…”

“…Tens of studies have documented occurrence of neonatal herpes for over 4 decades in Europe in countries such as Denmark, 45 France, 43 Germany, 46 , 47 Ireland, 48 Israel, 49 , 50 , 51 the Netherlands, 52 , 53 , 54 , 55 , 56 , 57 , 58 Poland, 59 , 60 Russia, 61 Spain, 62 Sweden, 63 , 64 , 65 Switzerland, 66 Turkey, 67 and the United Kingdom (UK). 48 , 68 , 69 , 70 , 71 , 72 , 73 , 74 , 75 , 76 , 77 , 78 However, surveillance for this condition remains overall limited with no data being reported for the majority of countries in Europe.…”

“…Reporting quality also varies widely from reports indicating sporadic cases to well-conducted epidemiologic studies based on surveillance systems and reporting estimates for incidence at a national level, such as in the Netherlands 52 , 53 , 54 , 55 , 56 , 57 and the UK. 48 , 69 , 71 , 72 , 73 , 74 , 75 …”

“…Of 59 reported cases in the UK during 2019–2021, 29 (49.2%) were due to HSV-1, 25 (42.4%) were due to HSV-2, and the remaining 5 (8.5%) had unknown HSV type. 48 …”

“…44 By type of infection, incidence in Europe was estimated at 5.2 cases per 100,000 live births for HSV-1 and at 3.8 cases per 100,000 live births for HSV-2. 44 Tens of studies have documented occurrence of neonatal herpes for over 4 decades in Europe in countries such as Denmark, 45 France, 43 Germany, 46,47 Ireland, 48 Israel, [49][50][51] the Netherlands, [52][53][54][55][56][57][58] Poland, 59,60 Russia, 61 Spain, 62 Sweden, [63][64][65] Switzerland, 66 Turkey, 67 and the United Kingdom (UK). 48,[68][69][70][71][72][73][74][75][76][77][78] However, surveillance for this condition remains overall limited with no data being reported for the majority of countries in Europe.…”