146b: Spectroscopic (Multi-Energy) Ct: The Future of Medical Imaging

Abstract

Introduction:The goal of this work is to develop spectroscopic (multi-energy) computed tomography (CT) systems for pre-clinical research. Traditional radiographs CT work by passing a broad spectrum of x-rays through the patient. The radiograph is formed by measuring the total number of x-rays that reach the detector (e.g. film). However, it has been known for a long time that x-rays come in different energies, also called wavelengths, frequency or colors. Methods:Our system uses the latest x-ray detectors from high energy physics to enable multi-energy imaging. This allows us to distinguish different materials in the object by their "x-ray color". Current state of the art clinical systems use two x-ray sources in order to have dual-energy imaging.Results and Discussion: Potential applications are improved use of pharmaceutical contrast agents (e.g. iodine and barium), improved intrinsic tissue contrast (calcium-oxylate versus calcium-phosphate in breast micro-calcifications) and labeling of tumor specific nano-particles. This exciting new tool has potential use for all branches of medicine.