Vitamin D status and prevalence of hypovitaminosis D in different genders throughout life stages: A Brazilian cross-sectional study

Leao, Lenora; Rodrigues, Bernardo; Dias, Paulo Telles Pires; Gehrke, Bárbara; Souza, Thiago da Silva Pereira de; Hirose, Caio Kenji; Freire, Monica Di Calafiori

doi:10.6061/clinics/2021/e2571

Cited by 12 publications

(7 citation statements)

References 53 publications

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“…The median vitamin D baseline values were high, but within the range of a previous study in Rio de Janeiro (n = 24,074) in which samples were analysed between February and April 2018 [38]. The vitamin D synthesis response to UVR is inversely proportional to baseline status [39], thus the high baseline will have decreased the sensitivity of the behavioural responses to the app.…”

Section: Discussionsupporting

confidence: 48%

Innovative digital solution supporting sun protection and vitamin D synthesis by using satellite-based monitoring of solar radiation

Young

Schalka

Temple

et al. 2022

Photochem Photobiol Sci

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Public health campaigns advise minimising UV radiation (UVR) exposure to prevent skin cancer and precancer, e.g. actinic keratosis (AK). A 3-day clinical field study, in Brazil, was performed to evaluate the mobile app Sun4Health® by siHealth Ltd. The app performs real-time monitoring of both erythemal and vitamin D-effective solar radiation doses using satellite data, enabling personalised recommendations on optimal sun exposure time and sunscreen use. When coupled to a wearable device, the app also provides body-site specific recommendations ("3D" version). 59 healthy volunteers were randomised into 3 groups, each given a different app providing: (1) ultraviolet index only (control app), (2) personalised recommendations and sun overexposure alerts (Sun4Health® app), (3) as ( 2) but connected via Bluetooth to a wearable device to monitor sun exposure in 3D (Sun4Health®-3D app). Participants were offered sunscreens (SPF 30 and 50) to use at their discretion. Erythema, quantified by reflectance spectroscopy, was assessed daily in the mornings and evenings on six body sites. Serum vitamin D (25(OH)D 3 ) was measured before and after the study. Mean increase of erythema (Mexameter® units ± SD) of all exposed body sites combined over 3 days showed 55.76 ± 47.47 for group 1, 40.27 ± 37.91 for group 2 and 37.12 ± 30.69 for group 3 (p < 0.05 for all groups). Mean increase of serum 25(OH)D 3 (nmol/l ± SD) showed 1.32 ± 36.49 for group 1, 6.38 ± 21.19 for group 2 and 18.68 ± 35.45 for group 3 (p > 0.05 for all groups). The results show that the Sun4Health® app is safe to use and can modify behaviour to reduce skin erythema (sunburn) yet not decreasing vitamin D status.

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Section: Discussionsupporting

confidence: 48%

Innovative digital solution supporting sun protection and vitamin D synthesis by using satellite-based monitoring of solar radiation

Young

Schalka

Temple

et al. 2022

Photochem Photobiol Sci

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“…Tem se observado que mesmo em regiões tropicais, a prevalência da hipovitaminose D vem aumentando gradativamente nos últimos anos (Landa et al, 2020;Leão et al, 2021). O Brasil está localizado em uma região geográfica com boa incidência de raios ultravioletas (UVB), durante todo o ano.…”

Section: Resultsunclassified

Deficiência e insuficiência da vitamina D em uma coorte da população de Pernambuco, Brasil

Maia

Correia²,

Silva³

et al. 2022

RSD

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A vitamina D tem um importante papel na imunidade e sua deficiência ou insuficiência (hipovitaminose D) pode estar relacionada com o aumento da prevalência das doenças autoimunes. Em um estudo de coorte retrospectivo com amostras simples, advindas de um banco de dados hospitalar público, foi verificado o perfil de vitamina D de uma população. Participaram da pesquisa 2.977 pacientes de 127 municípios de Pernambuco, Brasil. Em 12,6% dos municípios foram encontradas médias normais de vitamina D (D≥30ng/ml) e em 87,4% hipovitaminose D (concentração sérica de D <30ng/mL). Recife expôs o maior número de habitantes com deficiência de vitamina D (321) e apresentou 100% da amostra feminina (n=650) com hipovitaminose D (D<30ng/ml). A deficiência de vitamina D (D≤20ng/mL) neste município foi identificada em 20,3% da amostra e a insuficiência (D≥20ng/mL<30ng/mL) em 79,7%. Nas cidades circunvizinhas a Recife, a média de deficiência de vitamina D foi 13,3% e a de insuficiência 86,7%. Com relação ao envolvimento da hipovitaminose D com doenças autoimunes, os artigos do estudo ressaltaram a associação da hipovitaminose D com o risco de doenças autoimunes. Quanto à prevalência da hipovitaminose D nas doenças autoimunes, 93,0% dos artigos concordaram com esta associação. Sobre a influência da hipovitaminose D na atividade da doença autoimune, 63,6% reconheceram esta associação. A predominância da hipovitaminose D está se agravando, principalmente, na população feminina e sem distinção de

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“…Several infections like tuberculosis, respiratory and digestive pathway infections and acute otitis can be prevented by vitamin D therapy. However, excess vitamin D is also a reason for some critical issues [11][12] . The more accurate function of DBP is to maintain the level of free circulating and bounded vitamin D and its metabolites.…”

Section: Discussionmentioning

confidence: 99%

Bacterial Organisms Causing Urinary Tract Infection and their Correlation with Vitamin-D Deficiency in Pediatric Patients Presenting at Tertiary Care Hospital in Pakistan

Yunus¹,

Ali²,

Javed³

et al. 2022

PJMHS

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Background: Urinary tract infection is very common among the pediatrics. The systematic effects of vitamin D on the pathogens showed its vital role in immune regulation of the body. Objective: The study aimed to assess the status of vitamin-D in the children suffering from urinary tract infection. Study design: It is a cross-sectional study with statistical approach, conducted at HBS Medical and Dental College / HBS General Hospital Islamabad Material and Methods: The study was conducted on 91 patients visited the pediatric department of the hospital. The study was conducted for six month duration From November 2021 to April 2022. Out of the 91 patients included, the 53 were kept in the experimental group and 38 were kept in the control group. The average age of the patients who participated in this study was 3.86 ± 2.93 years in the case of experimental group while the other hand average age of the patients in the control group was 3.15 ± 3.02. Results: For this study, 91 patients were selected. Among these 91 patients, 53 were kept in the experimental group and 38 were kept in the control group. The average age of the patients who participated in this study was 3.86 ± 2.93 years in the case of experimental group while the other hand average age of the patients in the control group was 3.15 ± 3.02. The patients suffering from some UTI infections have a relatively lower level of vitamin D. For UTI infections, E. coli is the most common agent. However, other microbes are also thought to be the causative agent for this infection like P. aeruginosa, K. pneumonia, S. aureus, etc. Conclusion: Vitamin D is present in less amount in patients suffering from some urinary tract infections. Therefore a relationship exists between the level of vitamin D and urinary tract infections. Therefore by this study, we can predict that vitamin D therapy can be used to treat UTIs and prevent their repetition. For UTI infections, E. coli is the most common agent.However, there is a need for a large scale study for the more elaborated validations of this study. Keywords: Vitamin D, urinary tract infection and pediatrics.

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Vitamin D status and prevalence of hypovitaminosis D in different genders throughout life stages: A Brazilian cross-sectional study

Cited by 12 publications

References 53 publications

Innovative digital solution supporting sun protection and vitamin D synthesis by using satellite-based monitoring of solar radiation

Innovative digital solution supporting sun protection and vitamin D synthesis by using satellite-based monitoring of solar radiation

Deficiência e insuficiência da vitamina D em uma coorte da população de Pernambuco, Brasil

Bacterial Organisms Causing Urinary Tract Infection and their Correlation with Vitamin-D Deficiency in Pediatric Patients Presenting at Tertiary Care Hospital in Pakistan

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