Arterial stiffness in type 2 diabetes: determinants and indication of a discriminative value

Monteiro, Clara Italiano; Simões, Rodrigo Polaquini; Goulart, Cássia da Luz; Silva, Claudio Donisete da; Silva, Audrey Borghi; Mendes, Renata Gonçalves

doi:10.6061/clinics/2021/e2172

Cited by 7 publications

(4 citation statements)

References 35 publications

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“…[40][41][42] Clinicians should also be aware that elevated nighttime BP and arterial stiffness might be more likely in individuals with comorbidities such as chronic kidney disease, diabetes, and obstructive sleep apnea. [43][44][45] Including a bedtime dose of antihypertensive therapy may help to improve overall control of ambulatory BP and avoid the harmful nondipper pattern of nighttime BP in individuals with resistant hypertension. 46 A key strength of this study is the novelty of the analyses, which investigate associations between control of home BP and ambulatory BP measured using the same device for the first time.…”

Section: Discussionmentioning

confidence: 99%

Different Home Blood Pressure Thresholds to Predict Perfect 24-Hour Ambulatory Blood Pressure Control in Treated Hypertension Based on an “All-in-One” Device

Kario,

Tomitani,

Hoshide

et al. 2023

Hypertension

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BACKGROUND: Home blood pressure (BP) is an important component of digital strategies for hypertension management. However, no studies have used the same device to investigate 24-hour BP control status in relation to different home BP control thresholds. METHODS: Participants in the general practitioner-based, multicenter HI-JAMP study (Home-Activity Information and Communication Technology-Based Japan Ambulatory Blood Pressure Monitoring Prospective) underwent office BP measurement, then 24-hour ambulatory BP monitoring, then home BP monitoring for 5 days. A validated all-in-one BP monitoring device was used to measure office, home, and ambulatory BP. Baseline data were used to investigate ambulatory BP control status in individuals with well-controlled home BP based on the different guideline thresholds (125/75 mm Hg, 130/80 mm Hg, and 135/85 mm Hg). RESULTS: Data from 2269 patients were analyzed. For individuals with well-controlled home BP <135/85 mm Hg (59.5% of the total population), the prevalence of uncontrolled 24-hour (≥130/80 mm Hg), daytime (≥135/85 mm Hg), and nighttime ambulatory BP (≥120/70 mm Hg) was 19.9%, 18.5%, and 33.6%, respectively. Corresponding prevalence rates in the 42.7% of participants with well-controlled home BP <130/80 mm Hg were 13.4%, 12.9%, and 26.0%, and when well-controlled home BP was strictly defined as <125/75 mm Hg (23.9% of the population), prevalence of rates of uncontrolled 24-hour, daytime, and nighttime ambulatory BP were 7.0%, 9.0%, and 15.3%, respectively. CONCLUSIONS: Home BP control status defined using different thresholds could predict 24-hour ambulatory BP control status in treated hypertension. One-third of individuals still had uncontrolled nocturnal hypertension when home BP was controlled to <135/85 mm Hg, but ambulatory BP was quite well controlled when home BP was <125/75 mm Hg.

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Section: Discussionmentioning

confidence: 99%

Different Home Blood Pressure Thresholds to Predict Perfect 24-Hour Ambulatory Blood Pressure Control in Treated Hypertension Based on an “All-in-One” Device

Kario,

Tomitani,

Hoshide

et al. 2023

Hypertension

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“…Some studies indicate that arterial stiffness predicts T2DM incidence and that poor glycemic control and dyslipidemia are arterial stiffness determinants in T2DM. 31 A longitudinal study found that arterial stiffness precedes increased FBG, 32 probably because it is caused by glycation-mediated enhanced vascular aging and artery elasticity decline. 33 This is a complex process.…”

Section: Discussionmentioning

confidence: 99%

“…The study involved 685,277 participants who underwent at least 2 visits for a physical assessment between 2010 and 2016 at 32 sites in 11 Chinese cities. Follow up began after health examinations had been completed in 2010 and stopped upon detection of diabetes or on 31…”

Section: Study Populationmentioning

confidence: 99%

Association of Pulse Pressure Difference and Diabetes Mellitus in Chinese People: A Cohort Study

Wu¹,

Ma²,

Chen³

2021

IJGM

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Purpose: Here, we sought to determine the association between pulse pressure difference and the incidence of type 2 diabetes mellitus (T2DM) in Chinese people. Methods: This study involved 211,814 participants among whom 4156 had been diagnosed with T2DM. The correlation between pulse pressure difference and T2DM incidence in Chinese people was determined by multivariate analysis. A smooth curve fitting diagram was then used to explore correlation between pulse pressure difference and T2DM incidence. Finally, the inflection point in the correlation between pulse pressure difference and the T2DM incidence was located by piecewise linear regression. Results: To understand the relationship, adjustments were made for sex, age, total serum cholesterol (TC), fasting blood glucose (FPG), triglyceride (TG), alanine aminotransferase (ALT), family history of diabetes, body mass index (BMI), blood urea nitrogen (BUN), drinking status, and smoking status. Diabetes incidence increased by 0.3% [HR 1.003 (1.001, 1.005), p = <0.05] for every 1mmHg increase in pulse pressure difference. Smooth curve analysis showed that, when pulse pressure difference was ≤35mmHg, diabetes incidence negatively correlated to pulse pressure difference [HR 0.972 (0.953, 0.972) p = 0.053]. However, when pulse pressure difference was >35mmHg, diabetes incidence increased with increasing pulse pressure difference [HR 1.044 (1.042, 1.047) p = <0.001]. And between pulse pressure difference and fasting blood glucose in the final visit, the blood glucose level increased with the elevation of pulse pressure. Conclusion:The risk of diabetes was lowest at about 35mmHg pulse pressure difference.

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“…A hiperglicemia crônica pode causar apoptose celular e lesões em órgãos e tecidos-alvo 5 . A hiperglicemia tem sido associada à rigidez arterial 6 , disfunção endotelial seguida de arteriosclerose 7 , e doenças cardiovasculares, principalmente em mulheres 8,9 , as quais são as mais afetadas pelas internações e apresentam maior risco de mortalidade decorrente de diabetes mellitus 10 .…”

Section: Introductionunclassified

Acute blood glucose responses on the second day of recovery from moderate vs. high intensity resistance exercise in women with type 2 diabetes

et al. 2022

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Arterial stiffness in type 2 diabetes: determinants and indication of a discriminative value

Cited by 7 publications

References 35 publications

Different Home Blood Pressure Thresholds to Predict Perfect 24-Hour Ambulatory Blood Pressure Control in Treated Hypertension Based on an “All-in-One” Device

Different Home Blood Pressure Thresholds to Predict Perfect 24-Hour Ambulatory Blood Pressure Control in Treated Hypertension Based on an “All-in-One” Device

Association of Pulse Pressure Difference and Diabetes Mellitus in Chinese People: A Cohort Study

Acute blood glucose responses on the second day of recovery from moderate vs. high intensity resistance exercise in women with type 2 diabetes

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