The Challenges of Controlling Arterial Hypertension in the Elderly

Malachias, Marcus Vinícius Bolivar

doi:10.5935/abc.20190020

Cited by 18 publications

(17 citation statements)

References 10 publications

(14 reference statements)

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“…An automated and validated Microlife device was used to measure the systolic blood pressure (SDP) and diastolic blood pressure (DBP), and a mean of the 2 measurements was considered. The pulse pressure was calculated by the difference between the SDP and DBP [ 17 ]. Among the transgender group, 8 subjects were hypertensive, and all were on regular use of antihypertensive drugs.…”

Section: Methodsmentioning

confidence: 99%

“…Changes in the structural and functional properties of the large arteries are correlated with increased cardiovascular risk in different populations [ 15 , 16 ]. Nonclassical cardiovascular risk markers, such as arterial stiffness estimated by carotid–femoral pulse wave velocity (cf-PWV) measurements and carotid structure evaluated by carotid intima–media thickness measurements, are recommended by different guidelines for the complementary assessment of subclinical atherosclerosis and as predictors of additional cardiovascular risk [ 17 , 18 ].…”

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confidence: 99%

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Arterial Stiffness in Transgender Men Receiving Long-term Testosterone Therapy

Cunha

Bachega

Costa

et al. 2023

Journal of the Endocrine Society

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Context The effects of androgen therapy on arterial function in transgender men (TM) are not fully understood, particularly concerning long-term androgen treatment. Objective To evaluate arterial stiffness in TM receiving long-term gender-affirming hormone therapy by carotid-femoral pulse wave velocity (cf-PWV). Design A cross-sectional case-control study. Setting Gender Dysphoria Unit of the Division of Endocrinology, HC-FMUSP, Sao Paulo, Brazil. Patients Thirty-three TM receiving intramuscular testosterone (T) esters as regular treatment for an average time of 14 ± 8 years were compared to 111 healthy cisgender men and women controls matched for age and body mass index (BMI). Aortic stiffness was evaluated by cf-PWV measurements using the Complior® device post-testosterone therapy. Main outcome measures Aortic stiffness by carotid-femoral pulse wave velocity (cf-PWV) as a cardiovascular risk marker in transgender men and control group. Results The cf-PWV after long-term testosterone therapy was significantly higher in TM (7.4 ± 0.9 m/s; range: 5.8–8.9 m/s) than in cisgender men (6.6 ± 1.0 m/s; range: 3.8–9.0 m/s, p < 0.01) and cisgender women controls (6.9 ± 0.9 m/s; range: 4.8–9.1 m/s, p = 0.02). The cf-PWV was significantly and positively correlated with age. Analysis using blood pressure as a covariate showed a significant relationship between TM SBP and cf-PWV in relation to cisgender women but not to cisgender men. The age, the SBP and the diagnosis of hypertension were independently associated with cf-PWV in transgender men group. Conclusions The TM group on long-term treatment with testosterone had higher aging-related aortic stiffening than the control groups. These findings indicate that aortic stiffness might be accelerated in the TM group receiving the gender-affirming hormone treatment, and suggest a potential deleterious effect of testosterone on arterial function. Preventive measures in TM individuals receiving testosterone treatment, who are at higher risk for cardiovascular events, are highly recommended.

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Section: Methodsmentioning

confidence: 99%

mentioning

confidence: 99%

Arterial Stiffness in Transgender Men Receiving Long-term Testosterone Therapy

Cunha

Bachega

Costa

et al. 2023

Journal of the Endocrine Society

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“…A adoção das definições e da normatização de PA do "National High Blood Pressure Education Program" (NHBPEP) 2004, promoveu uniformidade na classificação da PA na população pediátrica (MALACHIAS, et al, 2016).…”

Section: Hipertensão Arterial Em Adolescentesunclassified

Educação física e qualidade de vida: reflexões e perspectivas atuais

Silva¹,

Soares²,

Barros³

2023

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Os autores desta obra: 1. Atestam não possuir qualquer interesse comercial que constitua um conflito de interesses em relação ao artigo científico publicado; 2.Declaram que participaram ativamente da construção dos respectivos manuscritos, preferencialmente na: a) Concepção do estudo, e/ou aquisição de dados, e/ou análise e interpretação de dados; b) Elaboração do artigo ou revisão com vistas a tornar o material intelectualmente relevante; c) Aprovação final do manuscrito para submissão.; 3. Certificam que os artigos científicos publicados estão completamente isentos de dados e/ou resultados fraudulentos; 4. Confirmam a citação e a referência correta de todos os dados e de interpretações de dados de outras pesquisas; 5.Reconhecem terem informado todas as fontes de financiamento recebidas para a consecução da pesquisa; 6. Autorizam a edição da obra, que incluem os registros de ficha catalográfica, ISBN, DOI e demais indexadores, projeto visual e criação de capa, diagramação de miolo, assim como lançamento e divulgação da mesma conforme critérios da Atena Editora. DECLARAÇÃO DA EDITORA A Atena Editora declara, para os devidos fins de direito, que: 1. A presente publicação constitui apenas transferência temporária dos direitos autorais, direito sobre a publicação, inclusive não constitui responsabilidade solidária na criação dos manuscritos publicados, nos termos previstos na Lei sobre direitos autorais (Lei 9610/98), no art. 184 do Código Penal e no art. 927 do Código Civil; 2. Autoriza e incentiva os autores a assinarem contratos com repositórios institucionais, com fins exclusivos de divulgação da obra, desde que com o devido reconhecimento de autoria e edição e sem qualquer finalidade comercial; 3. Todos os e-book são open access, desta forma não os comercializa em seu site, sites parceiros, plataformas de ecommerce, ou qualquer outro meio virtual ou físico, portanto, está isenta de repasses de direitos autorais aos autores; 4. Todos os membros do conselho editorial são doutores e vinculados a instituições de ensino superior públicas, conforme recomendação da CAPES para obtenção do Qualis livro; 5. Não cede, comercializa ou autoriza a utilização dos nomes e e-mails dos autores, bem como nenhum outro dado dos mesmos, para qualquer finalidade que não o escopo da divulgação desta obra.Educação física e qualidade de vida: reflexões e perspectivas atuai Capítulo 1

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“…In the elderly, there is an increase in the prevalence of cardiovascular diseases, their risk factors and also the presence of multiple morbidities (ABRIGNANI et al, 2020). Systemic arterial hypertension (SAH) is most predominant among the elderly and has a strong relationship with coronary artery disease and cerebrovascular accidents (MALACHIAS, 2019).…”

Section: Introductionmentioning

confidence: 99%

Chronic effect of bioresonance therapy on cardiovascular risk factors and physical activity pattern in the elderly: a randomized clinical trial

Mattera

Candeloro

Mora³

et al. 2023

CLIUM

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The aim of the study was to analyze the effect of 12 months of bioresonance therapy on physical activity behavior and cardiovascular risk factors in the elderly. A randomized, parallel, double-blind clinical trial was carried out in a sample of 20 elderly people. Bioresonance therapy was performed using QUANTEC® PRO. Data on gender, sex and morbidities were obtained. As cardiovascular risk factors, body composition, blood pressure and biochemical profile were analyzed. The behavior change stage related to physical activity was verified by the transtheoretical model and the physical activity pattern evaluated by the Baecke questionnaire. The treatment group showed a significant reduction in total cholesterol, triglycerides, blood glucose, LDL-c and non-HDL-c, and an increase in HDL-c and physical activity and physical exercise scores. The placebo group, showed a regression in the behavior stage for physical activity. Based on the results, we conclude that instrumental biocommunication therapy using QUANTEC® can make a significant contribution to the health of the elderly, particularly in increasing physical activity level, maintaining blood glucose levels and improving the lipid profile.

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The Challenges of Controlling Arterial Hypertension in the Elderly

Cited by 18 publications

References 10 publications

Arterial Stiffness in Transgender Men Receiving Long-term Testosterone Therapy

Arterial Stiffness in Transgender Men Receiving Long-term Testosterone Therapy

Educação física e qualidade de vida: reflexões e perspectivas atuais

Chronic effect of bioresonance therapy on cardiovascular risk factors and physical activity pattern in the elderly: a randomized clinical trial

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