Genetic Evaluation, Familial Screening and Exercise

Stein, Ricardo; Trujillo, Juan Pablo Fernández; Silveira, Anderson Donelli da; Júnior, Arsonval Lamounier; Iglesias, Lorenzo Monserrat

doi:10.5935/abc.20170015

Cited by 2 publications

(2 citation statements)

References 32 publications

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“…More recent studies have highlighted the role of genetic study in the "molecular autopsy" of individuals without anatomical changes who died suddenly. 77 - 79 A comprehensive analysis of genes related to SD in subjects who died suddenly during exercise has identified potential causative variants. However, the effects of many genetic variants are still undetermined and further study is needed to understand their clinical significance.…”

Section: Genetic Evaluation and Exercisementioning

confidence: 99%

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The Brazilian Society of Cardiology and Brazilian Society of Exercise and Sports Medicine Updated Guidelines for Sports and Exercise Cardiology - 2019

Ghorayeb¹,

Stein²,

Daher³

et al. 2019

Arquivos Brasileiros De Cardiologia

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Section: Genetic Evaluation and Exercisementioning

confidence: 99%

“…However, comprehensive genetic analysis of individuals who died during exercise could determine potential causative variants and help identify relatives at risk. 77 Specific recommendations about genetic analysis are addressed in the sections on inherited diseases in this Guideline.…”

Section: Genetic Evaluation and Exercisementioning

confidence: 99%

The Brazilian Society of Cardiology and Brazilian Society of Exercise and Sports Medicine Updated Guidelines for Sports and Exercise Cardiology - 2019

Ghorayeb¹,

Stein²,

Daher³

et al. 2019

Arquivos Brasileiros De Cardiologia

Self Cite

View full text Add to dashboard Cite

Genetic testing for exercise prescription and injury prevention: AIS-Athlome consortium-FIMS joint statement

et al. 2017

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BackgroundThere has been considerable growth in basic knowledge and understanding of how genes are influencing response to exercise training and predisposition to injuries and chronic diseases. On the basis of this knowledge, clinical genetic tests may in the future allow the personalisation and optimisation of physical activity, thus providing an avenue for increased efficiency of exercise prescription for health and disease.ResultsThis review provides an overview of the current status of genetic testing for the purposes of exercise prescription and injury prevention. As such there are a variety of potential uses for genetic testing, including identification of risks associated with participation in sport and understanding individual response to particular types of exercise. However, there are many challenges remaining before genetic testing has evidence-based practical applications; including adoption of international standards for genomics research, as well as resistance against the agendas driven by direct-to-consumer genetic testing companies. Here we propose a way forward to develop an evidence-based approach to support genetic testing for exercise prescription and injury prevention.ConclusionBased on current knowledge, there is no current clinical application for genetic testing in the area of exercise prescription and injury prevention, however the necessary steps are outlined for the development of evidence-based clinical applications involving genetic testing.

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Genetic Evaluation, Familial Screening and Exercise

Cited by 2 publications

References 32 publications

The Brazilian Society of Cardiology and Brazilian Society of Exercise and Sports Medicine Updated Guidelines for Sports and Exercise Cardiology - 2019

The Brazilian Society of Cardiology and Brazilian Society of Exercise and Sports Medicine Updated Guidelines for Sports and Exercise Cardiology - 2019

Genetic testing for exercise prescription and injury prevention: AIS-Athlome consortium-FIMS joint statement

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