Small cell lung carcinoma metastasis to palatine tonsils

Arroyo, Helena Hotz; Takehara, Jefferson; Ogawa, Allex Itar; Frizzarini, Ronaldo; Imamura, Rui; Paula, Henrique Moura de

doi:10.5935/1808-8694.20130117

Cited by 7 publications

(7 citation statements)

References 3 publications

(14 reference statements)

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“…Similar results were reported in another study published by Hyams and colleagues (2). Overall few cases of lung cancers with tonsillar metastasis were described and the majorities were small cell lung cancer (SCLC) (3)(4)(5)(6)(7)(8).…”

Section: Introductionsupporting

confidence: 82%

A rare case of palatin tonsillar metastasis from small cell lung cancer

D’Antonio¹,

Lombardini²,

Onesti³

et al. 2016

Transl. Lung Cancer Res.

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Tonsillar metastases are absolutely rare. Small cell lung cancer (SCLC) is known to be the most frequent histological type of tonsillar metastases, however the way of tumor cells spreading to tonsil remains controversial. We described a case report of 76-year-old man with SCLC and tonsillar metastases, to highlight the importance of oral cavity evaluation as a part of a clinical exam and to show the rare tumor cells spreading. We reported a case of synchronous tonsillar metastases in a SCLC patient with a similar survival compared to patients previously evaluated. For the purpose of a complete staging in cancer patients, especially in those with SCLC, we would highlight the importance of oral cavity evaluation as a part of a clinical exam. Keywords AcknowledgementsNone. Footnote Conflicts of Interest:The authors have no conflicts of interest to declare.

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Section: Introductionsupporting

confidence: 82%

A rare case of palatin tonsillar metastasis from small cell lung cancer

D’Antonio¹,

Lombardini²,

Onesti³

et al. 2016

Transl. Lung Cancer Res.

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show abstract

“…Pathways of metastasis to tonsils are not fully understood. However, several mechanisms are suggested: Because palatine tonsils do not have efferent lymphatic drainage, tumor cells are transported via retrograde route, and this is only possible in the absence of cervical lymphatic metastasis . Hematogenous, especially intra‐abdominal tumors thought to spread this way . By passing through the lungs by paravertebral plexus . It may be spread through direct inoculation during bronchoscopy. Especially, it is considered that lung cancer implements to the tonsils this way . …”

Section: Discussionmentioning

confidence: 99%

“…Because palatine tonsils do not have efferent lymphatic drainage, tumor cells are transported via retrograde route, and this is only possible in the absence of cervical lymphatic metastasis .…”

Section: Discussionmentioning

confidence: 99%

Tonsillar metastasis of small cell lung carcinoma

Ünsal

Kutlar

Süllü

et al. 2015

Clinical Respiratory J

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Metastasis to palatine tonsils are rare, accounting from only 0.8% of all tonsillar tumors, so far only 100 cases reported in the English literature. Only a few cases have been reported for small cell and non-small cell lung cancer as a primary site. With a diagnosis of small cell lung cancer, a 68-year-old male patient relapsed after six cycles of chemotherapy in tonsilla palatina and cervical lymph nodes. Patients died 26 months after being diagnosed with lung cancer and 2 months after detection of tonsil metastasis. We present the current case report because of the rarity of metastasis to tonsil in lung cancer.

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“…They include carcinoma of the breast, stomach, intestinal tract, kidney, skin and the lung. To the best of our knowledge, only 24 cases of lung cancer, mainly SCLC, have been reported to involve the tonsils, 22 the palatine and 2 the lingual tonsil [4][5][6][7][8][9][10].…”

Section: Discussionmentioning

confidence: 99%

Small Cell Lung Cancer with Isolated Unitonsillar Metastasis Successfully Treated with Chemotherapy

Fukuoka¹

2016

Arch Can Res

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Small cell lung carcinoma metastasis to palatine tonsils

Cited by 7 publications

References 3 publications

A rare case of palatin tonsillar metastasis from small cell lung cancer

A rare case of palatin tonsillar metastasis from small cell lung cancer

Tonsillar metastasis of small cell lung carcinoma

Small Cell Lung Cancer with Isolated Unitonsillar Metastasis Successfully Treated with Chemotherapy

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