Tonsillar metastasis of small cell lung carcinoma

Ünsal, Meftun; Kutlar, Gökhan; Süllü, Yüksel; Yurtlu, Şirin

doi:10.1111/crj.12275

Cited by 20 publications

(18 citation statements)

References 11 publications

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“…Similar results were reported in another study published by Hyams and colleagues (2). Overall few cases of lung cancers with tonsillar metastasis were described and the majorities were small cell lung cancer (SCLC) (3)(4)(5)(6)(7)(8).…”

Section: Introductionsupporting

confidence: 82%

A rare case of palatin tonsillar metastasis from small cell lung cancer

D’Antonio¹,

Lombardini²,

Onesti³

et al. 2016

Transl. Lung Cancer Res.

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Tonsillar metastases are absolutely rare. Small cell lung cancer (SCLC) is known to be the most frequent histological type of tonsillar metastases, however the way of tumor cells spreading to tonsil remains controversial. We described a case report of 76-year-old man with SCLC and tonsillar metastases, to highlight the importance of oral cavity evaluation as a part of a clinical exam and to show the rare tumor cells spreading. We reported a case of synchronous tonsillar metastases in a SCLC patient with a similar survival compared to patients previously evaluated. For the purpose of a complete staging in cancer patients, especially in those with SCLC, we would highlight the importance of oral cavity evaluation as a part of a clinical exam. Keywords AcknowledgementsNone. Footnote Conflicts of Interest:The authors have no conflicts of interest to declare.

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Section: Introductionsupporting

confidence: 82%

A rare case of palatin tonsillar metastasis from small cell lung cancer

D’Antonio¹,

Lombardini²,

Onesti³

et al. 2016

Transl. Lung Cancer Res.

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“…To the best of our knowledge, this is the first reported case of NECC metastasizing to the tonsil. Unsal et al . and Chen et al .…”

Section: Discussionmentioning

confidence: 85%

Rare case of tonsillar and subcutaneous metastasis from neuroendocrine cervical cancer

Zeng

Tuo

Liu

et al. 2020

J of Obstet and Gynaecol

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“…Compared with NSCLC, SCLC has a higher degree of malignancy and faster progression and metastasis (Donington et al, 2012;Unsal et al, 2016). Although SCLC patients are sensitive to radiochemotherapy, recurrence and metastasis always occur soon (Sas-Korczynska et al, 2013).…”

Section: Discussionmentioning

confidence: 99%

Association of PTEN Gene SNPs rs2299939 With PFS in Patients With Small Cell Lung Cancer Treated With Early Radiotherapy

et al. 2020

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Lung cancer has higher morbidity and mortality than most cancers. It is common that there are some phenomenons of secondary drug resistance, radiotherapy resistance and poor prognosis during the treatment of small cell lung cancer (SCLC). Recent studies revealed that the single-nucleotide polymorphisms (SNPs) are associated with the curative effect among patients with the same pathological type and stage. Our study analyzed the start time of radiotherapy and the relationship between PTEN gene rs2299939 polymorphisms and survival time among 116 SCLC patients. The results showed that early radiotherapy significantly improved the time of survival in patients compared with late radiotherapy (P = 0.029). Simultaneously, the study found that patients with the rs2299939 AA genotype showed significant sensitivity to both early and late radiotherapy, but early radiotherapy is better. The median survival time of CC genotype patients was 12 months in the early radiotherapy group while it was 9 months in the late radiotherapy group, thus recommending early radiotherapy among these patients. In addition, it was found that rs2299939 could regulate the expression of related genes in peripheral blood and lung tissues by eQTL analysis. This study revealed that the early radiotherapy could prolong the PFS of SCLC and shall be performed in SCLC treatment.

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Tonsillar metastasis of small cell lung carcinoma

Cited by 20 publications

References 11 publications

A rare case of palatin tonsillar metastasis from small cell lung cancer

A rare case of palatin tonsillar metastasis from small cell lung cancer

Rare case of tonsillar and subcutaneous metastasis from neuroendocrine cervical cancer

Association of PTEN Gene SNPs rs2299939 With PFS in Patients With Small Cell Lung Cancer Treated With Early Radiotherapy

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