Acute alcohol intoxication: uncommon complication associated to celiac plexus neurolysis during open surgical procedure in patient with refractory cancer pain. Case report

Afonso, Giselle Lima; Cardoso, Mirlane Guimarães de Melo; Coelho, Ivandete Pereira; Cardoso, Bárbara Guimarães de Melo

doi:10.5935/1806-0013.20160033

Cited by 3 publications

(4 citation statements)

References 9 publications

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“…Studies showed that complications particularly neurological ones associated to alcohol intoxication, was directly proportional to the alcohol mass injection and higher dose. 33 Mean administered volume, regardless of the technique, is approximately 15 mL. 34 In current study we have used 10 mL of 99.9% absolute alcohol.…”

Section: Discussionmentioning

confidence: 99%

Percutaneous Ultrasound Long Axis (In-plane)-guided Approach: A Novel Technique for Celiac Plexus Neurolysis in Patients with Advanced Pancreatic Cancer

Das¹,

Chansoria²,

Vyas³

et al. 2019

Journal on Recent Advances in Pain

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Introduction:The primary objective is to investigate the feasibility of proposed percutaneous ultrasound long axis (LA; in-plane) guided approach for celiac plexus neurolysis (CPN) in patients with advanced pancreatic cancer. The present study also aimed to assess the outcome as well as to document complications specific to the proposed technique if any. Materials and methods: Celiac plexus neurolysis under LA ultrasound (USG) guidance was performed in thirty one patients (mean age of 58.2 ± 4.7 years) of either-sex (24 men and 7 women) suffering from chronic pain due to pancreatic cancer [visual analog scale (VAS) score > 4] not responding to any pharmacological treatment or in those where opioids-related adverse effects are poorly tolerated. Follow-up was done immediately after injection, first day, 1 week, 4 weeks and 12 weeks following intervention and on an as needed basis thereafter. Post-neurolysis and at each subsequent follow-up visit, pain scores, satisfaction rate and other complications were studied. Level of statistical significance was set at a p < 0.05. Results: At 12 weeks CPN under LA ultrasound guidance was associated with significant pain relief, reduced NSAIDS/opioids consumption and improved patient satisfaction (p < 0.05). There were no major peri-and/or postoperative complications. Conclusion: Celiac plexus neurolysis under LA USG guidance enhances effectiveness and was associated with better pain relief, reduced NSAIDS/ opioids consumption and improved patient satisfaction. Clinical significance: Celiac plexus neurolysis under LA USG guidance enhances effectiveness of pain relief and level of safety in patients with abdominal malignancies.

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Section: Discussionmentioning

confidence: 99%

Percutaneous Ultrasound Long Axis (In-plane)-guided Approach: A Novel Technique for Celiac Plexus Neurolysis in Patients with Advanced Pancreatic Cancer

Das¹,

Chansoria²,

Vyas³

et al. 2019

Journal on Recent Advances in Pain

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“…The complications associated with splanchnic nerve block are rare and include hypotension, pneumothorax, chylothorax, abdominal symptoms, acute alcohol intoxication symptoms, infection, paraesthesia and nerve damage, vascular injection and damage, epidural or subarachnoid injections, organ puncture, and drug allergies [35,36]. As this as a sympathetic block, potential for hypotension is pretty high and fluid prophylaxis is necessary.…”

Section: Complicationsmentioning

confidence: 99%

Fluoroscopy-Guided Splanchnic Nerve Block for Cancer-Associated Pain

Paul¹,

Borkar²

2022

Cureus

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Pain associated with abdominal malignancies or metastasis can be very severe and can be intractable and resistant to conventional pharmacologic therapies. Typically, narcotics and non-narcotics are used in combination to alleviate the cancer pain, but these are often unsuccessful.Neurolysis and radio-frequency ablation of the celiac plexus and splanchnic nerves is being used with great success for management of the pain associated with abdominal malignancies with added advantages of improving quality of life, pain relief and decreased narcotic consumption. The tumor or associated lymphadenopathy may result in distortion of the celiac plexus anatomy, thus making it hard to reach the celiac plexus. In such cases, splanchnic nerve block can be employed with relative ease as compared to celiac plexus block.Given the nature of the debilitating pain associated with these conditions and inadequate pain relief with narcotics, these blocks are a boon in disguise to such patients with altered anatomy. Post administration of the splanchnic block, the functioning and quality of life of patients with abdominal malignancies improve. Hence, these blocks can be used to decrease the morbidity associated with abdominal malignancies.

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“…Surgical techniques for celiac plexus blockade and neurolysis using both the anterior and posterior approaches to the plexus have been published in the literature. CPN is performed by injecting ethanol into or by radiofrequency ablation of the celiac plexus, leading to permanent disruption of pain transmission 1 …”

Section: Introductionmentioning

confidence: 99%

“…CPN is performed by injecting ethanol into or by radiofrequency ablation of the celiac plexus, leading to permanent disruption of pain transmission. 1 Although CPN is a low-risk procedure, some adverse effects have been documented. Most of the effects are transient, and serious complications occur only in less than 2% of cases.…”

Section: Introductionmentioning

confidence: 99%

Persistent hypotension and other complications of celiac plexus neurolysis: A case report and literature review

Silva

Lopes

Bezerra³

et al. 2023

Clinical Case Reports

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Acute alcohol intoxication: uncommon complication associated to celiac plexus neurolysis during open surgical procedure in patient with refractory cancer pain. Case report

Cited by 3 publications

References 9 publications

Percutaneous Ultrasound Long Axis (In-plane)-guided Approach: A Novel Technique for Celiac Plexus Neurolysis in Patients with Advanced Pancreatic Cancer

Percutaneous Ultrasound Long Axis (In-plane)-guided Approach: A Novel Technique for Celiac Plexus Neurolysis in Patients with Advanced Pancreatic Cancer

Fluoroscopy-Guided Splanchnic Nerve Block for Cancer-Associated Pain

Persistent hypotension and other complications of celiac plexus neurolysis: A case report and literature review

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