Results of medium-term survival in patients undergoing cardiac transplantation: institutional experience

Abstract

Introduction The heart transplant became a consecrated therapy for patients with terminal heart failure, increasingly improving the survival. Objective To identify the medium-term results in patients undergoing cardiac transplantation. Methods This is a descriptive, documentary and retrospective study, using a quantitative approach, developed in a Unit of Transplant and Heart Failure, of a tertiary level public hospital, located in Fortaleza, CE, Brazil. The data were obtained from a sample of 188 patients (154 men and 34 women), submitted to the heart transplant, in the period from October 1997 to March 2011. There were calculated survival rates based on Kaplan-Meier methods. Results There were identified information about the patient's gender (male 81.91%), medical diagnosis which determined the heart transplantation (idiopathic cardiomyopathies 23.98%, ischemic 23.4% and Chagasic 17.02%). The median age of patients was 48 years old (interquartile range = 17.25 years) and the median observation period was 877 days. During this period, 78 patients died, resulting in survival ratios of 72%, 59% and 47% after 1, 5 and 9 years of cardiac transplantation, respectively. Younger patients had longer survival (P=0.0418). Conclusion The medium-term survival of patients undergoing cardiac transplantation is significant, especially for younger patients.

Influence Of The Conditioning Factors Of Cardiac Transplant Patients To The Self-Care Engagement Profile

“…It was observed, in relation to the conditioning factors for self-care, that the highest percentage of heart transplant patients were male, which result was similar in other studies [9,10]. In relation to the age, there was a prevalence of the range of 50 to 59 years (38.1%).…”

Patient-Related Preoperative Clinical Factors Influencing 1-Year Survival After Orthotopic Heart Transplantation – A Single Center Polish Experience

“…For example, in our population, the mean age at transplant was 53.5 (±11.8) years, whereas in Leiden [ 5 ], the mean age was 49 (±14) years; the difference may not be significant but shows a trend toward younger recipients. Furthermore, in the Brazilian population, the cause of transplantation was related to Chagas disease in 17.2% of patients [ 6 ], in contrast to our population, which had no cases of Chagas disease. Differences are also related to donors, organ procurement, immunosuppression, and periprocedural strategies [ 7 ].…”

Validation of the International Society for Heart and Lung Transplantation primary graft dysfunction instrument in heart transplantation

“…Two previous studies also observed a protective association between increasing recipient age and mortality. 10,11 One possible explanation for the protective association may be due to the confounding effect of congenital heart disease, as these patients are significantly younger compared with all other heart failure etiologies, and have the highest risk of 1-year mortality. 1 In addition, older heart transplant candidates are less likely to have comorbidities due to the careful candidate selection process, which could minimize their post-operative risk.…”