Complications of idiopathic thrombocytopenic purpura in pregnancy: a review of literature

Silva, Camila Lima da; Grando, Allyne Cristina

doi:10.5935/1676-2444.20210006

Cited by 4 publications

(5 citation statements)

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“…Aconselha-se evitar esportes que ofereçam tais riscos para a criança como: esportes de contato e colisão como futebol, atividades que envolvam altas velocidades como o uso de trampolim, pula-pula e bicicleta. Além disso, deve-se evitar o uso de medicamentos que prejudiquem a função plaquetária como os AINES (antiinflamatórios não esteroidais) bem como os anticoagulantes (SILVA et al, 2021) Nesse contexto, é sempre importante orientar a família através de medidas educativas, a estarem sempre monitorando sinais e sintomas de sangramento na criança.…”

Section: Trombocitopenia: Gestãounclassified

“…Segundo Grando et al, (2021), a Púrpura corresponde a uma doença que pode ser determinada pela extrusão dos capilares (pequenos vasos do sistema circulatório) ou por um distúrbio plaquetário. A ruptura dos capilares comumente é ocasionada por traumatismos na pele ou mucosas, gerando o advento das famosas petéquias ou equimoses.…”

Section: Introductionunclassified

“…De acordo com Silva et al, (2021), a PTI acomete tanto crianças como adultos, podendo ser considerada de acordo com a faixa etária em que se aparece e quanto ao tempo de evolução. É uma das causas mais comuns de plaquetopenia em crianças, com uma incidência anual em torno de 3 a 8 casos por 100.000 crianças, com maior número de casos entre os 2 a 5 anos de idade e com leve predomínio no sexo masculino.…”

Section: Introductionunclassified

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Idiopathic (Autoimmune) Thrombocytopenic Purpura: A Case Report

Dias,

Do Nascimento,

Nascimento

et al. 2024

Rev. Foco

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This report aims to describe a school patient, from the city of Juazeiro da Bahia, diagnosed with idiopathic thrombocytopenic purpura (autoimmune) and diagnosed with thrombocytopenia that had been sustained for months. Initially, he was diagnosed with dengue and anemia. Although this report describes a patient's favorable evolution, the relevance of carrying out future studies to evaluate the effects of thrombocytopenic purpura is highlighted. In short, this study aims to reference the most common findings through scientific literature as well as signs of worsening.

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Section: Trombocitopenia: Gestãounclassified

Section: Introductionunclassified

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Idiopathic (Autoimmune) Thrombocytopenic Purpura: A Case Report

Dias,

Do Nascimento,

Nascimento

et al. 2024

Rev. Foco

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show abstract

“…ITP is also typically more severe, with platelet counts <100,000/μL. 14 A peripheral smear should also be normal with the exception of fewer platelets and the presence of somewhat larger, immature platelets. 15 For most patients of reproductive age, a bone marrow aspirate is unnecessary for diagnosis, but may be helpful in atypical cases or patients who do not respond to usual therapy.…”

Section: Itpmentioning

confidence: 99%

“…While gestational thrombocytopenia typically presents later in pregnancy and resolves by 12 weeks postpartum, ITP can develop at any time from preconception throughout pregnancy, and can persist postpartum. ITP is also typically more severe, with platelet counts <100,000/μL 14. A peripheral smear should also be normal with the exception of fewer platelets and the presence of somewhat larger, immature platelets 15.…”

Section: Introductionmentioning

confidence: 99%

Maternal Coagulation Disorders and Postpartum Hemorrhage

Bank

Ma’ayeh²,

Rood

2023

Clinical Obstetrics &Amp; Gynecology

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Coagulation disorders are rare causes of postpartum hemorrhage. Disturbances in coagulation should be suspected in patients with a family history of coagulopathy, those with a personal history of heavy menstrual bleeding, and those with persistent bleeding despite correction of other causes. The coagulopathic conditions discussed include disseminated intravascular coagulation, platelet disorders, and disturbances of coagulation factors. These should not be overlooked in the evaluation of obstetric hemorrhage, as diagnosis and appropriate treatment may prevent severe maternal morbidity and mortality.

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Magnitude and associated factors of thrombocytopenia, among pregnant women at Mizan Tepi university teaching hospital south west Ethiopia

Kebede,

Daniel,

Alemu

et al. 2024

BMC Pregnancy Childbirth

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Background Thrombocytopenia in pregnancy is a common multifactorial abnormality of the hematological system, next to anemia. It leads to more increased risk of bleeding during delivery, labour, or the postpartum period. Despite being a significant public health concern, there are limited studies done concerning thrombocytopenia during pregnancy. Objective To assess the magnitude and associated factors of thrombocytopenia among pregnant women at Mizan Tepi University Teaching Hospital from September 2023 to November 2023. Methods An institutional-based cross-sectional study was carried out on 230 systematic randomly selected pregnant women who attended antenatal visits from September 2023 to November 2023 G.C using data collection tools. The pretested structured questionnaires were employed to obtain clinical, nutritional, and sociodemographic information. Additionally, three millilitres of venous blood were collected from each participant and analyzed using a Sysmex hematology analyzer. The data was entered into Epidata version 4.6 and analyzed using STATA version 14. Descriptive statistics were computed, and logistic regression was used to identify predictors with a significance level of less than 0.05. Results Two hundred thirty pregnant women participated in the study. Among study participants, the magnitude of thrombocytopenia was 55(24.35%) with 32 (57.14%) mild, 19 (33.93%) moderate, and 5 (8.93%) severe thrombocytopenia. The determinant factors which shown significant association were Malaria parasite infection (AOR 9.27 at 95% CI 7.42, 10.87), one-year Inter-birth interval (AOR 1.7 at 95% CI 1.24, 2.14), History of abortion (AOR 3.94 95% CI 3.13, 4.86), History of hypertension (AOR 3.12 95% CI 1.56, 4.12), HIV infection (AOR 1.81 95% CI 1.32.2.52) and HBV infection (AOR 3.0 95% CI 2.82, 3.34). Conclusion Thrombocytopenia is a public health problem and mild type of thrombocytopenia was the most predominant. The determinant factors that showed significant association with thrombocytopenia were Malaria Parasitic infection, one-year Inter-birth interval, History of abortion, History of hypertension, HIV infection, and HBV infection. Therefore, pregnant women should be continuously screened for thrombocytopenia to avoid excessive bleeding. Increasing Inter-birth interval, preventing abortion as well as timely diagnosis and treatment of underlying causes such as malaria infection, hypertension, HBV, and HIV is important to reduce the burden of thrombocytopenia.

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Complications of idiopathic thrombocytopenic purpura in pregnancy: a review of literature

Cited by 4 publications

References 0 publications

Idiopathic (Autoimmune) Thrombocytopenic Purpura: A Case Report

Idiopathic (Autoimmune) Thrombocytopenic Purpura: A Case Report

Maternal Coagulation Disorders and Postpartum Hemorrhage

Magnitude and associated factors of thrombocytopenia, among pregnant women at Mizan Tepi university teaching hospital south west Ethiopia

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