Synthesis and Antioxidant Activity of 1,4-[Bis(3-arylmethanesulfonyl pyrrolyl and pyrazolyl)]benzenes

Synthesis and biological evaluation of new spirooxindoles with embedded pharmacophores

“…This may be due to the presence of the electron releasing methoxy group at the ortho position of the quinoline, which may enhance the stabilization of the resulting oxygen radical. 28 In addition, the antioxidant properties of the synthesized compounds were in good agreement with antioxidant-enriched sources (vitamin C, which has a cyclic ester (lactone)). In view of the fact that oxindoles have very close structural similarity, oxindoles would be expected to show antioxidant properties, as they have cyclic amides (lactams), similar to the lactone in vitamin C. 29 2.2.1.2.…”

Synthesis, in vitro safety and antioxidant activity of new pyrrole hydrazones

“…Pyrroles and their derivatives represent one of the most important groups of N-heterocyclic compounds because of their remarkable antibacterial, antiviral, anti-inflammatory, antitumor, and antioxidant activities (1). Recent studies of different benzoxazolyl, benzothiazolyl, benzimidazolyl-pyrroles with amide structure have been reported, displaying greater antioxidant and radical scavenging activity when compared with the standard drug, ascorbic acid (2).…”

Rapid and Efficient Uncatalyzed Knoevenagel Condensations from Binary Mixture of Ethanol and Water

“…[1][2][3] It is one of the most useful reactions to form C-C bonds, generally used to assist the synthesis of several compounds with biological relevance 4 and other possible applications, such as drugs, [5][6][7][8][9][10] natural products, 11,12 and polymers. [13][14][15] Weak bases, such as amines and basic salts, usually catalyze these reactions.…”