Overview of hemodialysis treatment funded by the Brazilian Unified Health System - An economic perspective

Menezes, Fabiana Gatti de; Barreto, Daniela Veit; Abreu, Rodrigo Martins; Roveda, Fabiana; Filho, Roberto Flavio Silva Pecoits

doi:10.5935/0101-2800.20150057

Cited by 20 publications

(27 citation statements)

References 17 publications

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“…Chronic kidney disease is currently considered a public health problem because of its high prevalence [1][2][3][4] . The number of patients suffering from end-stage renal disease (ESRD) is expected to rise even more in developing countries, as there is an increase in the elderly population, a higher prevalence of cardiovascular diseases and improvement in their treatment, as well as persistent high rates of hypertensive and diabetic patients 1,[5][6][7] .…”

Section: Introductionmentioning

confidence: 99%

Effects of sertraline in the prevention of low blood pressure in patients undergoing hemodialysis

et al. 2019

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Introduction: Intradialytic hypotension (IDH) is a major complication of hemodialysis, with a prevalence of about 25% during hemodialysis sessions, causing increased morbidity and mortality. Objective: To study the effects of sertraline to prevent IDH in hemodialysis patients. Methods: This was a double-blind, crossover clinical trial comparing the use of sertraline versus placebo to reduce intradialytic hypotension. Results: Sixteen patients completed the two phases of the study during a 12-week period. The IDH prevalence was 32%. A comparison between intradialytic interventions, intradialytic symptoms, and IDH episodes revealed no statistical difference in the reduction of IDH episodes (p = 0.207) between the two intervention groups. However, the risk of IDH interventions was 60% higher in the placebo group compared to the sertraline group, and the risk of IDH symptoms was 40% higher in the placebo group compared to the sertraline group. Survival analysis using Kaplan-Meier estimator supported the results of this study. Sertraline presented a number needed to treat (NNT) of 16.3 patients to prevent an episode from IDH intervention and 14.2 patients to prevent an episode from intradialytic symptoms. Conclusion: This study suggests that the use of sertraline may be beneficial to reduce the number of symptoms and ID interventions, although there was no statistically significant difference in the blood pressure levels.

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Section: Introductionmentioning

confidence: 99%

Effects of sertraline in the prevention of low blood pressure in patients undergoing hemodialysis

et al. 2019

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“…Failure on the water treatment poses hemodialysis patients at risk of injury and death. Biofilm formation can occur due to the presence of microorganisms in the water system and, once established, acts as a permanent source of bacteria and endotoxins (Linde et al, 1999;Menezes et al, 2015). When present in the dialysis water, endotoxins may enter the blood compartment and potentially activate monocytes to produce pro-inflammatory cytokines, related to several distinct acute and chronic problems of hemodialysis patients (Linde et al, 1999;Garcia, Benitez, 2000).…”

Section: Introductionmentioning

confidence: 99%

“…In Brazil, epidemiological data show a gradual increase in the number of chronic renal patients under dialysis treatment during the last years, with direct costs of US$ 970 million per year (Sesso et al, 2016). The Southeastern region has the highest incidence rates of patients (51%) and the largest number of dialysis services in the country (Menezes et al, 2015;Sesso et al, 2016).…”

Section: Introductionmentioning

confidence: 99%

Is dialysis water a safe component for hemodialysis treatment in São Paulo State, Brazil?

Hilinski

Almodóvar

Silva

et al. 2020

Braz. J. Pharm. Sci.

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Failure on the water treatment poses hemodialysis patients at risk of injury and death. Identifying if the patients are exposed to water quality related microbiological risks is an important objective to reduce the mortality for chronic renal patients and is the main issue of this study. We evaluated the microbiological water quality used by 205 dialysis services in São Paulo State, Brazil between 2010 to 2016. The study included heterotrophic bacteria count, total coliforms research, and bacterial endotoxin determination in 1366 dialysis water samples. The number of unsatisfactory clinics for at least one microbiological parameter decreased 16.0% between 2010 to 2015 but increased 57.2% in 2016. In 2010, the most frequent unsatisfactory parameter was related to heterotrophic bacteria count (54.8%) followed by endotoxin determination (45.2%). However, in 2013 an opposite situation was observed: endotoxin determination as the parameter of the higher incidence of nonconformities. Total coliform was verified at a lower frequency. We highlighted the importance of regular monitoring of dialysis water quality to prevent infections caused by dialytic procedures and to ensure that the water is a safe component of the treatment.

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“…Contudo, Apesar de fundamental para estes pacientes, a utilização da hemodiálise como terapia renal substitutiva implica em elevado custo econômico e social. (MENEZES, 2015) Diante desta problemática, o objetivo do estudo foi analisar os custos e determinar o ponto de equilíbrio da unidade de hemodiálise do Hospital das Clínicas de Pernambuco em 2016. Estando este estudo justificado pela necessidade de se analisar os custos da unidade de hemodiálise, uma vez que esses procedimentos tendem a elevar os gastos para a instituição, refletindo diretamente na oferta desse tratamento (sessão de hemodiálise) aos pacientes e corroborando como subsídio para tomada de decisão dos gestores.…”

Section: Introductionunclassified

Custos Da Unidade De Hemodiálise Do Hospital Das Clínicas De Pernambuco Em 2016

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2017

Anais Do 5º Encontro Brasileiro Para Inovação Terapêutica

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Overview of hemodialysis treatment funded by the Brazilian Unified Health System - An economic perspective

Abstract: After data analysis, different aspects of hemodialysis use were demonstrated, with an increase in amount of procedures and, also, in disease related expenses.

Cited by 20 publications

References 17 publications

Effects of sertraline in the prevention of low blood pressure in patients undergoing hemodialysis

Effects of sertraline in the prevention of low blood pressure in patients undergoing hemodialysis

Is dialysis water a safe component for hemodialysis treatment in São Paulo State, Brazil?

Custos Da Unidade De Hemodiálise Do Hospital Das Clínicas De Pernambuco Em 2016

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