Clinical and epidemiological prevalence of glomerulopathies in older patients in the city of Uberaba - MG

Oliveira, Lethícia Borges; Côbo, Eliângela de Castro; Machado, Juliana Reis; Custódio, Fabiano Bichuette; Silva, Marcos Vinícius da; Oliveira, Flávia Aparecida de; Corrêa, Rosana Rosa Miranda; Reis, Marlene Antônia dos

doi:10.5935/0101-2800.20150027

Cited by 6 publications

(4 citation statements)

References 9 publications

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“…The present study demonstrated that the major clinical manifestations of biopsy-proven kidney diseases in the elderly were proteinuria and haematuria. NS was a common clinical manifestation (62.5%) in the elderly patients that were investigated in this present study, which was consistent with another report, 13 although the rate was a little higher in the present cohort. This difference in the rate of NS might be related to the reluctance of clinicians to undertake renal biopsies, patient’s preference, and life expectancy.…”

Section: Discussionsupporting

confidence: 93%

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Biopsy-proven kidney diseases in the elderly: clinical characteristics, renal histopathological spectrum and prognostic factors

Chen

Cui

et al. 2016

J Int Med Res

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ObjectiveTo explore the clinical characteristics, renal histopathological spectrum and prognostic factors of biopsy-proven kidney diseases in the elderly.MethodsA retrospective observational study was conducted in elderly patients who had received renal biopsies. Demographic, clinical and pathological data at the time of the biopsy were collected from the medical records. Follow-up records and prognostic factors were studied.ResultsThe elderly (≥60 years) accounted for 74 of 434 (17.1%) native renal biopsies that were performed in a 9-year period. In the cohort of included elderly patients (n = 72), the prevalence of nephrotic syndrome and acute kidney injury was 62.5% (45 of 72) and 40.3% (29 of 72), respectively. For elderly patients with primary glomerular diseases (n = 44), membranous nephropathy was the most frequent pathological type (24 of 44; 54.5%). For elderly patients with secondary glomerular diseases (n = 25), anti-neutrophil cytoplasmic antibody-associated vasculitis was the most frequent aetiology (nine of 25; 36.0%). Requirement for renal replacement therapy (RRT) was an independent risk factor for poor prognosis.ConclusionsKidney diseases in the elderly have distinctive characteristics. Requirement for RRT was associated with poor prognosis in the elderly with biopsy-proven kidney diseases.

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Section: Discussionsupporting

confidence: 93%

“…AUA manifested as proteinuria and/or haematuria without oedema, hypertension and renal dysfunction. 13 …”

Section: Methodsmentioning

confidence: 99%

Biopsy-proven kidney diseases in the elderly: clinical characteristics, renal histopathological spectrum and prognostic factors

Chen

Cui

et al. 2016

J Int Med Res

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“…There are also local studies that have evaluated specific populations, either by city or by age group, with fewer biopsies. [6][7][8] Due to the wide ethnic and socioeconomic diversity throughout Brazil, it is of considerable interest to gain knowledge regarding the regional peculiarities of glomerular diseases.…”

Section: Introductionmentioning

confidence: 99%

Comparative analysis of primary and secondary glomerulopathies in the northeast of Brazil: data from the Pernambuco Registry of Glomerulopathies - REPEG

Costa¹,

Valente²,

Gouveia³

et al. 2017

Jornal Brasileiro De Nefrologia

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“…In these cases, renal biopsy is an important method to confirm the etiology of this glomerular disease 2 . In Brazil, data regarding trends in glomerular and nonglomerular nephropathies confirmed by means of a renal biopsy are still limited to certain regions of the country [3][4][5][6] or based on sampling from hospitals/ nephrology centers 3,5,[7][8][9][10][11][12][13] . In Santa Catarina, there are no population data that can contribute to a better epidemiological understanding of the prevalence of nephropathies diagnosed through renal biopsy.…”

Section: Abstract Introductionmentioning

confidence: 99%

Distribution of kidney diseases in Joinville, Santa Catarina: analysis of a kidney biopsy data bank between 2008 and 2019

et al. 2022

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Introduction: Studies based on kidney biopsies are important for the epidemiological understanding of nephropathies. Objective: To describe the main nephropathies diagnosed through renal biopsies, and compare them with regards to gender, time, healthcare insurance and age. Methods: A population-based retrospective study that reviewed all kidney disease diagnoses obtained by biopsy of a native kidney from pathology services between 2008 and 2019 in Joinville, Brazil. Results: Of 778 biopsies performed, 44.5% were primary nephropathies and 28.5% were secondary. The highest prevalence was focal segmental glomerulosclerosis (FSGS) [18.1%], followed by tubulointerstitial nephropathy (TIN) [15.9%] and IgA nephropathy (IgAN) [9.1%]. There was a growing increase in the prevalence of TIN among elderly and uninsured patients over the period. In the multivariate analysis, among the primary glomerulopathies, males had a higher risk for the occurrence of IgAN [OR=2.02; 95% CI 1.13-3.61; p=0.018], as well as being a protective factor for the occurrence of lupus glomerulonephritis (LGN) [OR=0.20, 95% CI 0.08-0.49; p<0.001]. Advancing age and dependence on a public healthcare decreased the likelihood of having a diagnosis of LGN [OR=0.91, 95% CI 0.88-0.94, p < 0.001 and OR=0.45, CI 95 % 0.21-0.96; p = 0.036, respectively]. Patients without private healthcare insurance were more likely to have TIN [OR=1.77, 95%CI 1.16-2.70; p = 0.008]. Conclusion: Sex, age and type of medical healthcare insurance may be related to the occurrence of some nephropathies. The increased risk of TIN in individuals without a private healthcare plan may be an indication of inequalities in health care.

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Clinical and epidemiological prevalence of glomerulopathies in older patients in the city of Uberaba - MG

Cited by 6 publications

References 9 publications

Biopsy-proven kidney diseases in the elderly: clinical characteristics, renal histopathological spectrum and prognostic factors

Biopsy-proven kidney diseases in the elderly: clinical characteristics, renal histopathological spectrum and prognostic factors

Comparative analysis of primary and secondary glomerulopathies in the northeast of Brazil: data from the Pernambuco Registry of Glomerulopathies - REPEG

Distribution of kidney diseases in Joinville, Santa Catarina: analysis of a kidney biopsy data bank between 2008 and 2019

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