Anemia in chronic kidney disease in a Hospital in the Northwest region to the State of Rio Grande do Sul

Abstract

A doença renal crônica (DRC) constitui um importante problema de saúde pública. 1 No Brasil, censo realizado com unidades de diálise cadastradas na Sociedade Brasileira de Nefrologia Anemia na doença renal crônica em hospital da região noroeste do estado do Rio Grande do SulAnemia in chronic kidney disease in a Hospital in the Northwest region to the State of Rio Grande do Sul Introdução: A doença renal crônica (DRC) tem sido identificada em um número crescente de pacientes e, dentre suas consequências, encontra-se a anemia. Objetivo: Verificar a ocorrência de anemia em pacientes com DRC que realizavam hemodiálise em um hospital da Região Sul, Brasil, bem como seu perfil laboratorial renal e de ferro. Métodos: Realizou-se estudo retrospectivo descritivo analítico. Foram analisados 45 prontuários com resultados de exames desde o início do tratamento hemodialítico até nove meses após. Resultados: Mais de 50,0% dos pacientes apresentava hipertensão arterial e diabetes e 68,8% era do gênero masculino. A anemia esteve presente em 97,8% dos pacientes e foi tratada com eritropoetina e/ou ferro. No período avaliado, ocorreu aumento nas medianas dos níveis de hemoglobina (p < 0,001), hematócrito (p < 0,001), ferritina, creatinina (p < 0,001) e ureia pré (p = 0,039). A saturação de transferrina estava baixa em 35,6% dos pacientes após aproximadamente um ano de tratamento hemodialítico. Houve correlação entre creatinina e ureia, ambas elevando-se. Conclusão: Após a introdução de tratamento para anemia, ocorreu aumento dos níveis plasmáticos de hemoglobina e melhora do quadro, ainda que sem normalização completa desses níveis. resumo Palavras-chave: anemia; creatinina; eritropoetina; insuficiência renal crônica; ureia.Introduction: Chronic kidney disease (CKD) has been identified in an increasing number of patients and among its consequences is the anemia. Objective: To verify the occurrence of anemia in patients with CKD undergoing hemodialysis at a Hospital in the South Region, Brazil, as well as their kidney profile and iron profile. Methods: It was performed a retrospective, descriptive and analytical study. It was analyzed 45 patient records with results from the beginning of the hemodialysis treatment until nine months later. Results: Over 50.0% of the patients had hypertension and diabetes and 68.8% were male. The anemia was present in 97.8% of the patients and treated with erythropoietin and/or iron. In the evaluated period occurred increase in median hemoglobin levels (p < 0.001), hematocrit (p < 0.001), ferritin, creatinine (p < 0.001) and urea under (p = 0.039). The transferrin saturation was low in 35.6% of the patients after about one year under hemodialysis treatment. There was correlation between creatinine and urea, both rising. Conclusion: After the introduction of treatment for anemia occurred increased plasma levels of hemoglobin and clinical improvement, even though not having a complete normalization of these levels.

Correlation Between Chronic Kidney Diseases and Hematolgical Data in Sabratha Hospital in Libya

“…Although the etiology is not entirely clear, metabolic, and mechanical factors have been proposed [31,32]. In this study, reduction in Hb, RBCs count, and hematocrit is in accordance with the study of Poudel et al [33], Bueno and Frizzo, [34] and de Francisco et al [35].…”

Incidência E Fatores Predisponentes De Insuficiência Renal Aguda Em Unidade De Terapia Intensiva

“…No achado, a ureia constitui fator negativo e a creatinina um fator positivo. Nesse sentido, a creatinina constitui um indicador mais sensível da função do que a ureia, já que esta é afetada pela disfunção renal (29) , mas também pelo aporte proteico na dieta, catabolismo, nutrição parenteral e determinados medicamentos (corticosteroides) (18) .…”

Risk Factors for Anemia in Patients with Chronic Renal Failure: A Systematic Review and Meta-Analysis

“…Risk factors of anemia patients with CKD were obtained from various areas across the globe. Twelve studies involved participants from Africa (13)(14)(15)(38)(39)(40)(41)(42)(43)(44)(45)(46), nine from Asia (18,(47)(48)(49)(50)(51)(52)(53), four from Europe (28,(54)(55)(56), and three from America (9,11,57).With respect to the tools used to assess anemia in CKD patients, eleven studies (11,12,15,38,(43)(44)(45)48,49,52,57) used the WHO definition, nine studies (13,14,42,46,47,51,53,55,56) used the Kidney Disease Outcome Quality Initiative, and three studies (28,39...…”

“…Large differences have been reported on the magnitude of anemia in patients with CKD across studies. For instance, reports showed an anemia prevalence of 47.7% in the USA (9), 39.36% in India (10), 97.8% in Brazil (11), 51.5% in China (12), 79% in Cameroon (13), 43.18% in South Africa (14), and 64.5% in Ethiopia (15). In addition, African Americans had a 3-fold increased likelihood of anemia compared with whites (16).…”