Evaluation of short-term prognostic factors of ranibizumab in patients with dabetic macular edema

Kanadani, Tereza Cristina Moreira; Cotta, Bruna Stefane Silva; Souza, Anna Carollina Cardoso Rezende de; Costa, Ana Paula de Oliveira; Takahashi, Denise Matos

doi:10.5935/0034-7280.20180030

Cited by 2 publications

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“…The natural trajectory of type 2 Diabetes Mellitus (type 2 DM) is characterized by being multifactorial, however, insulin resistance and insulin secretion deficiency by β cells are the main factors in the pathogenesis of type 2 DM (Zhao, et al, 2017), which can cause changes in several organs and systems (Kanadani, et al, 2018). Therefore, people diagnosed with this disease are at greater risk of developing multiple complications (Carrera Boada & Martinéz-Moreno, 2013) that can be associated with physical limitations, causing important impairments in quality of life, especially in older adults.…”

Section: Introductionmentioning

confidence: 99%

Factors associated with the functional performance of older adults with type 2 Diabetes Mellitus

Dias

Carlos

Lemos

et al. 2020

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The aim of this study was to investigated factors associated with the functional impairment of older adult patients with type 2 diabetes mellitus (type 2 DM) and identify the influence of sociodemographic, clinical, and functional factors in this population. This is an observational analytical, and cross-sectional study, which evaluated 159 individuals of both genders, aged 60 years or older. The WHODAS (World Health Organization Disability Assessment Schedule) total score was analyzed in relation to other variables of the study, using the following statistical tests: Mann-Whitney, Kruskal-Wallis, Dunn’s post hoc, Spearman correlation, and simple linear regression analysis. Significance level was set at 5% (p<0.05). In total, 12 linear regression models were generated and the latter was selected for elaborating the prediction equation and its possible interpretations. Functional impairment was associated with sociodemographic, clinical, and functional factors. Sedentary lifestyle, overweight, cognitive deficit, decreased mobility, and falls were the factors that predicted the restriction of functional performance in older adults with type 2 DM. This study assessed the relationship between sociodemographic, clinical, and functional factors concerning the functional impairment of older adults with type 2 DM, reaffirming that this disease causes negative impacts in a global way and that the association among these factors leads to a decrease in functionality and worsening of life quality in this population. The findings of this study point out the importance of preventive programs in order to promote behavioral changes that can reduce the impact of type 2 DM complications.

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Section: Introductionmentioning

confidence: 99%

Factors associated with the functional performance of older adults with type 2 Diabetes Mellitus

Dias

Carlos

Lemos

et al. 2020

RSD

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“…DM2 is considered a potential cause of changes in postural balance (PB) 7 . Patients with diabetes often present with disorders in the sensory systems responsible for the maintenance of PB due to comorbidities such as retinopathy, peripheral neuropathy, and disorders in the vestibular system [7][8][9][10] .…”

Section: Introductionmentioning

confidence: 99%

Diseases and symptoms associated with changes in postural balance in diabetics: an integrating literature review

et al. 2019

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Purpose: to verify the diseases and symptoms associated with changes in postural balance in middle-aged and elderly individuals with type 2 diabetes mellitus. Methods: an integrative review was performed using the following descriptors: "Dizziness," "Vertigo," "Vestibular Diseases," "Labyrinth Diseases," and "Type 2, Diabetes Mellitus" in English and in Portuguese in databases such as PubMed, SciELO, LILACS, Web of Science, and Scopus. Observational articles involving individuals aged 40 years or more with type 2 diabetes mellitus and with alteration in postural balance having presented at least one disease or symptom associated with that alteration were selected. Results: the search yielded 1,209 articles, but only five met the eligibility criteria. Individuals in the selected studies had systemic arterial hypertension, high body mass index, peripheral neuropathy, and postural instability when walking on irregular surfaces and in the dark, when looking at moving objects, moving the head quickly and changing posture, resulting in stumbling when walking, and falls. The articles were classified as IIb and III, according to the levels of evidence of the American Speech-Language Hearing Association. Conclusion: the subjects in the studied articles presented cardiovascular alterations, peripheral neuropathy, vestibular symptoms, difficulties in tasks/movements in challenging contexts, and falls.

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Evaluation of short-term prognostic factors of ranibizumab in patients with dabetic macular edema

Cited by 2 publications

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Factors associated with the functional performance of older adults with type 2 Diabetes Mellitus

Factors associated with the functional performance of older adults with type 2 Diabetes Mellitus

Diseases and symptoms associated with changes in postural balance in diabetics: an integrating literature review

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