Relationship between optical coherence tomography findings and clinical variables in patients with opiate use disorder

Özsoy, Filiz; Kulu, Müberra; Özarslan, Yakup; Korkmaz, Sevda

doi:10.5935/0004-2749.20230013

ABO

2023

DOI: 10.5935/0004-2749.20230013

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Relationship between optical coherence tomography findings and clinical variables in patients with opiate use disorder

Filiz Özsoy¹,

Müberra Kulu²,

Yakup Özarslan³

et al.

Abstract: espessura da camada de fibra nervosa da retina. Nosso estudo deve ser apoiado por novos estudos com grupos de amostragem maiores, nos quais os achados de neuroimagem são avaliados. Descritores: Alcaloides opiáceos; Transtornos relacionados ao uso de opioides; Tomografia de coerência óptica; Espessura da camada de fibras nervosas da retina; Volume macular

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OCT Findings in Patients with Methamphetamine Use Disorder

Kaya

Kaya²

2023

JPM

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Purpose: In the present study, the purpose was to examine the results of optical coherence tomography (OCT) measurements in patients diagnosed with methamphetamine use disorder (MUD) by comparing them with healthy controls. Materials and Methods: A total of 114 eyes were evaluated in this study (27 patients and 30 control group participants). After detailed biomicroscopic examinations of all participants by the same ophthalmologist, both eyes were evaluated by OCT. The retinal nerve fiber layer thickness (RNFL) and macular thickness were calculated from OCT. Results: No statistically significant differences were detected between the demographic data of the patient and control groups (p > 0.05). When OCT findings were evaluated, macular thickness and volume were not different between the groups (p > 0.05). With respect to RNFL, the left eye superior, inferior, temporal, and nasal quadrants, as well as the left eye’s total measurements were found to be thicker than those of controls (p < 0.05). In both eyes, the left eye nasal quadrant and APIS total score were negatively correlated, the total RNLF measurement of the right eye and APIS motivation subscale score were negatively correlated, central macular thickness and the APIS motivation subscale score were positively correlated, and the APIS substance use characteristics subscale score and left eye temporal quadrant RNLF measurement were positively correlated. Conclusion: Our study is the first to evaluate addiction severity and OCT findings in MUD. However, this study needs to be supported by further studies so that OCT findings, which can be used as an effective method for demonstrating possible neurodegeneration in methamphetamine use disorder, gain importance.

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OCT Findings in Patients with Methamphetamine Use Disorder

Kaya

Kaya²

2023

JPM

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Relationship between optical coherence tomography findings and clinical variables in patients with opiate use disorder

Cited by 1 publication

References 23 publications

OCT Findings in Patients with Methamphetamine Use Disorder

OCT Findings in Patients with Methamphetamine Use Disorder

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