Eﬀects of obesity on retrobulbar ﬂow hemodynamics: color Doppler ultrasound
            evaluation

Çekiç, Bülent; Toslak, İclal Erdem; Doğan, Berna; Çakır, Tuğrul; Erol, Muhammet Kazım; Bülbüller, Nurullah

doi:10.5935/0004-2749.20170036

Cited by 11 publications

(19 citation statements)

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“…These results were consistent with our previous study, 22 suggesting that we must take SSI value into consideration when comparing retinal VD values. Although obesity was found to be associated with reduction of retrobulbar blood flow velocity, 28 our results did not suggest any correlation between BMI nor waist circumference and NFLP VD. In this study, there were only 70 (5%) participants having a BMI ≥30 kg/m 2 , 25 (5%) men having a waist circumference >102 cm and 204 (23%) women having a waist circumference >88 cm.…”

Section: Clinical Sciencecontrasting

confidence: 92%

Optic disc and peripapillary vessel density measured with optical coherence tomography angiography and its associations in Chinese adults: a large population-based study

et al. 2021

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PurposeTo investigate the optic disc and peripapillary vessel density, as well as its ocular and systemic associations, in healthy eyes among adult Chinese population.MethodsA population-based cross-sectional eye survey was conducted on Chinese adults residing in Hong Kong. 1891 eyes from 1891 participants who completed 4.5×4.5 mm optical coherence tomography angiography scans were recruited. Among the 1891 eyes, 404 were excluded due to low scan quality, optic disc or retinal disorders and non-Chinese ethnicity. The vessel densities (VDs) at nerve fibre layer plexus (NFLP) at both optic disc and peripapillary were collected for analysis. Multiple linear regression analysis was performed to determine the ocular and systemic associations of NFLP VD.ResultsThe study included 1487 participants (men: 41.2%) with a mean age of 48.8±15.4 years. The mean NFLP VD of the whole en face image, inside disc and peripapillary region was 53.8%, 42.7% and 60.3%, respectively. In the multivariable model, decreased NFLP VDs were significantly associated with older age, male gender, longer axial length (AL) and lower Signal Strength Index.ConclusionsThis large population-based cross-sectional study provided quantitative data of optic disc and peripapillary NFLP VD which may serve as a normative reference for clinical use. Apart from age, gender and AL, the scan signal strength also should be taken into consideration during the assessment of NFLP VD.

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Section: Clinical Sciencecontrasting

confidence: 92%

Optic disc and peripapillary vessel density measured with optical coherence tomography angiography and its associations in Chinese adults: a large population-based study

et al. 2021

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“…The exact pathophysiology of elevated IOP in obesity remains unclear. Possible mechanisms that can explain such association include: obesity-related oxidative stress [ 26 ] leading to trabecular meshwork malfunctioning [ 27 ], increased orbital fat impeding aqueous outflow [ 28 ], and dysregulation of retrobulbar blood flow [ 29 ].…”

Section: Obesity and Energy Intakementioning

confidence: 99%

The Role of Diet in Glaucoma: A Review of the Current Evidence

Owaifeer

Taisan

2018

Ophthalmol Ther

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Intraocular pressure (IOP) reduction by medications, laser, or surgery remains the mainstay of treatment in glaucoma. However, the role of complementary and alternative medicine (CAM) in glaucoma has received great interest from both patients and ophthalmologists. Previous evidence suggests that diet, a major domain of CAM, can influence an individual’s IOP level. Furthermore, certain dietary components have been linked to the incidence and progression of glaucoma. In this review, we aim to provide a summary of the current evidence regarding the role of obesity, certain dietary components, and dietary supplements in glaucoma.

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“…When we compare the morbid obese studies' results with this current study, we observed that the CRA-PSV tends to be the more affected subparameter in relation to the severity of the obesity among the retrobulbar blood ow parameters and without a vascular resistance change in less obese cases. Similarly, another study has found a decrease only in the OA PSV and EDV values together with decreased CRA PI in morbidly obese patients [7]. On the other hand, the elevated blood cell count, hemoglobin and hematocrit values in obese patients result in an increase in the blood viscosity [19].…”

Section: Discussionmentioning

confidence: 93%

“…Previous studies have focused on retrobulbar ocular blood ow or choroidal thickness changes, but not both. Only two previous studies have evaluated the effect of obesity on retrobulbar ocular blood ow, and these have only included morbid obese patients [6,7]. The above parameters are clinically important as they are part of the ocular circulation, and are also essential in guiding the clinical approach to whether subjects suffering from obesity of various degrees have an increased risk of ocular pathology development.…”

Section: Introductionmentioning

confidence: 99%

Ocular Blood Flow Abnormalities and Their Correlation with Body Mass Index in Obese Patients

Tüfek¹,

Çapraz²,

Kaya³

et al. 2021

Preprint

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PurposeTo evaluate the effects of obesity on ocular blood flow including choroidal thickness and retrobulbar blood flow values in comparison with healthy subjectsMethodsThe 102 eyes of 102 female patients were included in this prospective study.Color Doppler ultrasonography (CDU) was used to evaluate the retrobulber vessels.Choroidal thickness was measured by using the optical coherence tomography (OCT). ResultsThere was a significant difference in IOP values within the groups with the highest values in group 3 and the lowest in group 1.There was also a positive correlation between BMI and IOP. The CT was found to be statistically significantly lower in group 2 and group 3 than in the control group at all measurement points. The choroidal thickness was also statistically significantly lower in group 3 than in group 2 at the subfoveal, nasal 500 µm, and the temporal 500 and 1000 µm measurement points.The mean CRA PSV and EDV values were lower in group 2 and group 3 than in group 1, while group 3 had the lowest mean CRA PSV value among the groups. When compared to group 1, the OA EDV value was lower only in group 3 while the OA PSV value was statistically significantly lower in group 3 than in both group 2 and group 1. There was no significant difference between the groups in terms of RI and PI.ConclusionsObesity can create a predisposition to ocular pathologies both by increasing the IOP and decreasing the retrobulbar and choroidal blood flow.

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Eﬀects of obesity on retrobulbar ﬂow hemodynamics: color Doppler ultrasound evaluation

Abstract: Obese patients have a higher mean IOP and lower flow velocity than non-obese patients. Increased IOP together with decreased retrobulbar blood flow, particularly in obese individuals, may increase the risk of glaucoma development.

Cited by 11 publications

References 0 publications

Optic disc and peripapillary vessel density measured with optical coherence tomography angiography and its associations in Chinese adults: a large population-based study

Optic disc and peripapillary vessel density measured with optical coherence tomography angiography and its associations in Chinese adults: a large population-based study

The Role of Diet in Glaucoma: A Review of the Current Evidence

Ocular Blood Flow Abnormalities and Their Correlation with Body Mass Index in Obese Patients

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