2018
DOI: 10.5123/s1679-49742018000500001
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Abstract: Paracoccidioidomycosis is a systemic fungal disease associated with agricultural activities. Its incidence and prevalence are underestimated because of the lack of reporting in several Brazilian states. If paracoccidiodomycosis is not diagnosed and treated early and adequately, endemic fungal infection may result in serious sequelae. In addition to the Paracoccidioides brasiliensis (P. brasiliensis) complex, the appearance of a new species, Paracoccidioides lutzii (P. lutzii), in Rondônia state, where the dise… Show more

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Cited by 36 publications
(52 citation statements)
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“…PMC more commonly affects farm workers and/or people who live in rural areas, particularly males in the ratio of 15:1, smokers and/or chronic alcoholics, aged between 30 and 50 years 2,4,5 . This unequal distribution has been attributed to two main factors, namely: 1) the greater exposure of men to soil and 2) the role of estrogen, which inhibits the transformation of the mycelial form of the microorganisms to the yeast form, which is pathogenic 2,4 . These factors corroborate with the case reported here since the 50 years old patient was a smoker for over thirty years, alcoholic and worked in rural areas.…”
Section: Discussionmentioning
confidence: 99%
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“…PMC more commonly affects farm workers and/or people who live in rural areas, particularly males in the ratio of 15:1, smokers and/or chronic alcoholics, aged between 30 and 50 years 2,4,5 . This unequal distribution has been attributed to two main factors, namely: 1) the greater exposure of men to soil and 2) the role of estrogen, which inhibits the transformation of the mycelial form of the microorganisms to the yeast form, which is pathogenic 2,4 . These factors corroborate with the case reported here since the 50 years old patient was a smoker for over thirty years, alcoholic and worked in rural areas.…”
Section: Discussionmentioning
confidence: 99%
“…Most cases of PCM begin with pulmonary involvement after exposure to spores 4 . Inhalation of P. brasiliensis leads to infection even without manifestation of active disease 2 .…”
Section: Discussionmentioning
confidence: 99%
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