Efeitos do exercicio físico em parâmetros moleculares da via de sinalização da insulina e obesidade

Farias, Joni Marcio de

doi:10.5007/1980-0037.2014v16n5p588

Rev. Bras. Cineantropom. Desempenho Hum.

2014

DOI: 10.5007/1980-0037.2014v16n5p588

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Efeitos do exercicio físico em parâmetros moleculares da via de sinalização da insulina e obesidade

Joni Marcio de Farias

Abstract: Effects of physical exercise in molecular parameters of the route of obesity and insulin signaling Efeitos do exercicio físico em parâmetros moleculares da via de sinalização da insulina e obesidade

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2016

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Imobilização articular: efeitos sobre o tecido muscular de camundongos obesos e desnutridos

Rissi

Lemos

Ide

et al. 2016

Rev. Bras. Cineantropom. Desempenho Hum.

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-Although it is a widely used resource for the treatment of musculoskeletal injuries, immobilization causes deleterious effects in muscle tissue after a short period of time. This study aimed to evaluate the gastrocnemius and tibialis anterior muscles of obese and protein malnourished animals under joint immobilization condition. Overall, 28 adult male mice were used (C57 / BL6), being divided into four groups (N = 7): Control Group (CG), Immobilized Control Group (ICG), Immobilized Obese Group (IOG) and Immobilized Malnourished Group (IMG). The immobilization protocol was performed by the use of adhesive tape and plaster. The conditions and obesity and protein malnutrition have been developed through the ingestion of diets specific for each group of animals. The histomorphometric analysis of muscles evaluated area and the diameter of muscle fibers. All immobilized groups showed reduction in the area and diameter of muscle fibers when compared to GC. Comparisons among immobilized groups showed that the area and diameter of muscle fibers of IOG and IMG were lower than ICG. The immobilization protocol caused reduction in muscle trophism in animals, and obese and malnourished animals suffered high losses under condition of muscle atrophy.Key words: Immobilization; Muscular atrophy; Protein malnutrition; Obesity. Resumo -Embora seja um recurso muito utilizado para tratamento de lesões musculoesqueléticas, a imobilização causa efeitos deletérios no tecido muscular após curto período de tempo. O presente estudo teve como objetivo avaliar os músculos gastrocnêmio e tibial anterior de animais obesos e desnutridos proteicamente sob a condição de imobilização articular. Foram utilizados 28 camundongos (C57/BL6) machos adultos, distribuídos em quatro grupos (N=7): Grupo controle (GC), Grupo Controle Imobilizado (GCI), Grupo Obeso imobilizado (GOI) e Grupo Desnutrido Imobilizado (GDI

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Imobilização articular: efeitos sobre o tecido muscular de camundongos obesos e desnutridos

Rissi

Lemos

Ide

et al. 2016

Rev. Bras. Cineantropom. Desempenho Hum.

View full text Add to dashboard Cite

show abstract

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Efeitos do exercicio físico em parâmetros moleculares da via de sinalização da insulina e obesidade

Abstract: Effects of physical exercise in molecular parameters of the route of obesity and insulin signaling Efeitos do exercicio físico em parâmetros moleculares da via de sinalização da insulina e obesidade

Cited by 1 publication

References 39 publications

Imobilização articular: efeitos sobre o tecido muscular de camundongos obesos e desnutridos

Imobilização articular: efeitos sobre o tecido muscular de camundongos obesos e desnutridos

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