Eficácia comparativa de duas formulaÇões de uso tópico contendo fipronil 10ij no controle de Ctenocephalides felis felis em gatos

Abstract

The goal of the present study was to evaluate the comparative efficacy of two topical formulations containing 10% fipronil on the control of Ctenocephalides felis felis on cats. The trial was performed at the Laboratory of Experimental Chemotherapy in Veterinary Parasitology from the Department of Animal Parasitology of the Institute of Veterinary of the Universidade Federal Rural do Rio de Janeiro. Eighteen mixed-breed cats were divided in three groups of six animals each. One group remained without treatment (control). The other groups received as treatment the two topical formulations, a commercial reference and the novel one, both containing 10% fipronil. Treated animals received 0.5 mL of product along their cervical region. Cats were infested on days - 2, +5, +12, +19, +26 and +33. Evaluations were made using the "comb test". The first one was undertaken 4 days after the initial infestation (day +2), and others 48 hours after following infestations (days +7, +14, +21, +28 and + 35). Both tested formulations had satisfactory efficacy until day + 35. No differences were observed comparing the efficacy levels between both formulations throughout the experimental period. The novel topical 10% fipronil formulation presented desirable efficacy on the control of C. f. felis on cats.

Acaricidal efficacy of topical formulation of fipronil in naturally infested dogs in Amazonic region, Brazil

“…In Brazil, several studies have described the therapeutic efficacy in dogs and other species naturally and experimentally infested with ticks and fleas (TANCREDI et al, 2009;PAIM et al, 2011), but no studies have tested the efficacy of Fipronil in dogs in the particular conditions of the Amazon region climate. It is necessary to emphasize that the natural feature of the Rainforest, characterized by heavy rainfall, can affect the efficiency of topical formulations on the control of ticks' populations (GROSSCURT, 1993).…”