Escore Albumina-Bilirrubina para Predizer Desfechos em Pacientes com Cardiomiopatia Dilatada Idiopática

Jiang, Mei; Wei, Xuebiao; Huang, Jun; Su, Zedazhong; Lin, Yingwen; Yu, Danqing

doi:10.36660/abc.20210035

Cited by 6 publications

(1 citation statement)

References 28 publications

(26 reference statements)

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“…Moreover, the ALBI score is used for the prediction of mortality in valvular surgery, 17) heart failure, 18) and idiopathic dilated cardiomyopathy. 19) With these evidences into consideration, ALBI score can be applied to non-HCC patients. The Child-Pugh score has been widely used for the assessment of prognosis with the combination of liver cirrhosis, which contains ascites, hepatic encephalopathy, prothrombin time, albumin, and bilirubin.…”

Section: Discussionmentioning

confidence: 99%

Effect of Ceftriaxone Dosage and Albumin–Bilirubin Score on the Risk of Ceftriaxone-Induced Liver Injury

Ooi,

Asai,

Koriyama

et al. 2023

Biological & Pharmaceutical Bulletin

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The albumin-bilirubin (ALBI) score is an index of hepatic functional reserve and is calculated from serum albumin and total bilirubin levels. However, the relationship between ceftriaxone (CTRX)-induced liver injury and ALBI score remains unknown. Therefore, we aimed to elucidate the risk of CTRX-induced liver injury based on the ALBI scores and CTRX dosage. This was a single-center, retrospective, case-control study of 490 patients and the primary outcome was CTRX-induced liver injury. We performed a COX regression analysis using age ≥75 years, male sex, alanine aminotransferase levels, ALBI score, and CTRX dosage regimen (4 ≥2 or 1 g/d) as explanatory factors. We also performed 1 : 1 propensity score matching between non-liver injury and liver injury groups. The incidence of liver injury was 10.0% (49/490). In COX regression analysis, CTRX 4 g/d was an independent risk factor for liver injury (95% coefficient interval: 1.05-6.96, p 0.04). Meanwhile, ALBI score ≥ 1.61 was an independent factor for liver injury (95% coefficient interval: 1.03-3.22, p 0.04) with the explanatory factor of ≥2 and 1 g/d. The Kaplan-Meier curve indicated that the cumulative risk for CTRX-induced liver injury was significantly higher in the ALBI score ≥ 1.61 group than in the ALBI score < 1.61 group before propensity score matching (p 0.032); however, no significant differences were observed after propensity score matching (p 0.791). These findings suggest that in patients treated with CTRX with ALBI score ≥ 1.61, frequent liver function monitoring should be considered.

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Section: Discussionmentioning

confidence: 99%

Effect of Ceftriaxone Dosage and Albumin–Bilirubin Score on the Risk of Ceftriaxone-Induced Liver Injury

Ooi,

Asai,

Koriyama

et al. 2023

Biological & Pharmaceutical Bulletin

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Risk evaluation of ampicillin/sulbactam-induced liver injury based on albumin-bilirubin score

Ooi¹,

Asai²,

Sato³

2023

Journal of Infection and Chemotherapy

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The relationship between echocardiographic parameters and albumin bilirubin (ALBI) score in patients with isolated secundum type atrial septal defect

et al. 2023

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Background It has been shown that the increase in volume and pressure in the right heart chambers increases liver stiffness. The Albumin‐Bilirubin (ALBI) score is a useful and easy‐to‐use score for objectively assessing liver function. There is no information in the literature about changes in ALBI score in patients with atrial septal defect (ASD). The aim of our study is to investigate the changes in ALBI score and its clinical impact in patients with ASD. Methods Of the 206 analyzed patients, 77 were excluded. The remaining 129 patients with secundum type ASD with left to right shunt were divided into three groups; Group I (16 patients with Qp/Qs < 1.5 and defect diameter < 10 mm), Group II (52 patients with Qp/Qs > 1.5 and defect diameter 10–20 mm) and Group III (61 patients with Qp/Qs > 1.5 and defect diameter > 20 mm). The ALBI score was calculated based on serum albumin and total bilirubin levels using the following formula: ALBI = (log10 bilirubin [umol/L] * .66) + (albumin [g/L] * ‐.085). Results ALBI scores as well as total bilirubin levels, transaminases, and functional‐structural heart abnormalities (increase in RA and RV dimensions, sPAP, ASD size and decrease in LVEF and TAPSE) showed a significant increasing trend from Group I to Group III (p < .001 for all comparisons). The mean ALBI scores for Group I, Group II, and Group III were ‐3.71 ± .37, ‐3.51 ± .25, and ‐3.27 ± .34, respectively. In multivariate linear regression analysis, ASD size, sPAP, RV‐RA diameter were found to be significantly associated with increased ALBI score. Conclusion The ALBI score offers a simple, evidence‐based, objective, and discriminatory method of assessing liver function in patients with ASD. ASD size, sPAP, RV and RA diameters were significantly associated with ALBI score.

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Escore Albumina-Bilirrubina para Predizer Desfechos em Pacientes com Cardiomiopatia Dilatada Idiopática

Cited by 6 publications

References 28 publications

Effect of Ceftriaxone Dosage and Albumin–Bilirubin Score on the Risk of Ceftriaxone-Induced Liver Injury

Effect of Ceftriaxone Dosage and Albumin–Bilirubin Score on the Risk of Ceftriaxone-Induced Liver Injury

Risk evaluation of ampicillin/sulbactam-induced liver injury based on albumin-bilirubin score

The relationship between echocardiographic parameters and albumin bilirubin (ALBI) score in patients with isolated secundum type atrial septal defect

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