Tuberculosis: a deadly and neglected disease in the COVID-19 era

Maciel, Ethel Leonor Nóia; Golub, Jonathan E.; Silva, José Roberto Lapa e; Chaisson, Richard E.

doi:10.36416/1806-3756/e20220056

Cited by 5 publications

(8 citation statements)

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“…It should be remembered that COVID-19 had a major impact on TB treatment, as it caused additional challenges beyond epidemiological surveillance, at the national and international levels, and in the recognition of the need for public policies aimed at reducing inequalities in access to systems health and the urgent reduction of social injustice ( 18 ) .…”

Section: Discussionmentioning

confidence: 99%

“…According to Maciel et al . ( 18 ) , COVID-19 and TB are different diseases, with different impacts on public health, establishing different government actions to combat them, without correct investments for control and innovation for both diseases. In Brazil, funding for TB did not reach 0.1% of the total amount allocated to science and technology in all areas at the time of the pandemic.…”

Section: Discussionmentioning

confidence: 99%

“…Cumpre lembrar que ocorreu grande impacto da COVID-19 no tratamento da TB, uma vez que ocasionou desafios adicionais para além da vigilância epidemiológica, na esfera nacional e internacional, e no reconhecimento da necessidade de políticas públicas voltadas à diminuição das desigualdades de acesso aos sistemas de saúde e da urgente redução da injustiça social ( 18 ) .…”

Section: Discussionunclassified

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Social protection in areas vulnerable to tuberculosis: a mixed methods study in São Luís, Maranhão

Aragão,

Calori,

Berra

et al. 2024

Rev. Bras. Enferm.

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Objectives: to analyze the risk areas for tuberculosis and the influences of social protection on the development of treatment for the disease in the municipality of São Luís, Maranhão. Methods: this is explanatory sequential mixed method research. In the quantitative phase, the data were obtained from the Notifiable Diseases Information System from 2010 to 2019, with georeferencing being carried out to identify areas vulnerable to tuberculosis. In the qualitative phase, semi-structured interviews were carried out with individuals who received social benefits. Results: 7,381 cases were geocoded, and, from the purely spatial scanning analysis, it was possible to identify 13 spatial clusters of risk. As for the interviews, there was a positive relationship between patient improvement and receiving benefits. Conclusions: geographic space and social determinants are relevant for reorienting monitoring actions for the conditions that generate the health-disease process.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionunclassified

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Social protection in areas vulnerable to tuberculosis: a mixed methods study in São Luís, Maranhão

Aragão,

Calori,

Berra

et al. 2024

Rev. Bras. Enferm.

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“…(1) This scenario becomes even more complex and worrying when we consider that tuberculosis disproportionately affects underdeveloped and developing countries and the most socioeconomic vulnerable groups. (2) Regarding this context, WHO launched the "End Tuberculosis Strategy", an international proposal that aims to eliminate the global tuberculosis epidemic. (3) This strategy is anchored in pillars of research and innovation, support systems, and integrated patientcentered care and prevention.…”

Section: Introductionmentioning

confidence: 99%

A critical analysis of the decreasing trends in tuberculosis cure indicators in Brazil, 2001–2022

Pavinati1,

Vinícius de Lima1,

Paiva Bernardo1

et al. 2024

J Bras Pneumol.

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Objective: To analyze the temporal trend of tuberculosis cure indicators in Brazil. Methods: An ecological time-series study using administrative data on reported cases of the disease nationwide between 2001 and 2022. We estimated cure indicators for each federative unit (FU) considering individuals with pulmonary tuberculosis, tuberculosis-HIV coinfection, and those in tuberculosis retreatment. We used regression models using joinpoint regression for trend analysis, reporting the annual percentage change and the average annual percentage change. Results: For the three groups analyzed, we observed heterogeneity in the annual percentage change in the Brazilian FUs, with a predominance of significantly decreasing trends in the cure indicator in most FUs, especially at the end of the time series. When considering national indicators, an average annual percentage change of -0.97% (95% CI: -1.23 to -0.74) was identified for the cure of people with pulmonary tuberculosis, of -1.11% (95% CI: -1.42 to -0.85) for the cure of people with tuberculosis-HIV coinfection, and of -1.44% (95% CI: -1.62 to -1.31) for the cure of people in tuberculosis retreatment. Conclusions: The decreasing trends of cure indicators in Brazil are concerning and underscore a warning to public authorities, as they point to the possible occurrence of other treatment outcomes, such as treatment discontinuity and death. This finding contradicts current public health care policies and requires urgent strategies aiming to promote follow-up with patients during tuberculosis treatment in Brazil.

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“…De acordo com Maciel et al (2022), a COVID-19 e a tuberculose são doenças diferentes, com impactos distintos na saúde pública, estabelecendo ações diferenciadas dos governos; todavia, sem investimentos corretos, a inovação para o controle de qualquer doença continua bastante limitada. No Brasil, o financiamento para a TB não atingiu 0,1% do valor total alocado para a ciência e tecnologia em todas as áreas na época da pandemia.…”

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A proteção social em áreas vulneráveis à tuberculose: um estudo misto em São Luís, Maranhão

Aragão¹

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Em primeiro lugar, agradeço a Deus, pelo dom da vida e por me permitir concluir mais essa etapa da minha trajetória acadêmica, por estar comigo nos momentos mais difíceis, e por ter me concedido saúde e graça durante os quatros anos do doutorado, toda honra e glória sejam dadas a Deus por mais essa vitória. A ele, minha eterna gratidão.À minha orientadora, Professora Dra. Regina Célia Fiorati, pela confiança depositada, pelos ensinamentos, pelas oportunidades e experiências vividas no decorrer dessa jornada.À minha Coorientadora, Professora Dra. Mellina Yamamura Calori, pelas experiências acadêmicas e ensinamentos compartilhados.Ao Professor, Dr. Ricardo Alexandre Arcêncio, que ao me apresentar a minha orientadora, possibilitou a realização deste projeto de pesquisa, minha eterna gratidão.Aos meus pais, Francisco e Marluce, por me incentivarem a todo momento e por confiarem na minha capacidade para vencer os obstáculos, meu amor eterno a vocês que me ensinaram a ser uma mulher forte e guerreira.Aos meus irmãos, Raissa, Janaína e Bruno, que sempre me apoiaram em minha jornada, obrigada por tudo, vocês moram no meu coração. Aos meus sobrinhos, Marone, Issac e Francisco Renato, por serem luz e minha alegria constantes.Ao Professor Marcelino Santos Neto, pela parceria estabelecida e conhecimentos compartilhados.Ao meu amigo, José Henrique, pelo suporte e conselhos que renovaram as minhas forças e me ajudaram a prosseguir. À Thais Zamboni Berra, do Grupo de Estudos Epidemiológico-Operacional em Tuberculose (GEOTB), que me ajudou na parte quantitativa do projeto de pesquisa.Às minhas amigas, Joelmara Furtado, Andréa Reis, Samara Letícia e Andrea Suzana, por me ouvirem nos momentos mais difíceis e me estimularem a prosseguir no meu objetivo, aumentando a minha fé a cada instante.

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Tuberculosis: a deadly and neglected disease in the COVID-19 era

Cited by 5 publications

References 4 publications

Social protection in areas vulnerable to tuberculosis: a mixed methods study in São Luís, Maranhão

Social protection in areas vulnerable to tuberculosis: a mixed methods study in São Luís, Maranhão

A critical analysis of the decreasing trends in tuberculosis cure indicators in Brazil, 2001–2022

A proteção social em áreas vulneráveis à tuberculose: um estudo misto em São Luís, Maranhão

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