Inflammatory myopathies in childhood: correlation between nailfold capillaroscopy findings and clinical and laboratory data

Nascif, Ana Karina Soares; Terreri, Maria Teresa; Len, Cláudio Arnaldo; Andrade, Luís Eduardo Coelho; Hilário, Maria Odete Esteves

doi:10.2223/jped.1435

Cited by 32 publications

(13 citation statements)

References 21 publications

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“…Several studies have reported that the intensity of the morphological changes on NFC correlate with the clinical course and the more severe forms of disease, such as ulcerative complications and calcinosis. [27][28][29][30] In our study, disease activity was associated with capillaroscopic changes, indicating that NFC is an adequate method to monitor the course of JDM.…”

Section: Discussionmentioning

confidence: 85%

Capilaroscopia periungueal em crianças e adolescentes com doenças reumáticas

Piotto¹,

Len²,

Hilário³

et al. 2012

Rev. Bras. Reumatol.

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Objective: To assess nailfold capillaroscopy in children and adolescents with autoimmune rheumatic diseases (juvenile idiopathic arthritis, systemic lupus erythematosus, juvenile dermatomyositis, scleroderma and mixed connective tissue disease) and relate it to clinical and laboratory fi ndings and disease activity. Methods: Cross-sectional study assessing 147 patients by use of nailfold capillaroscopy as follows: 60 with juvenile idiopathic arthritis; 30 with systemic lupus erythematosus; 30 with juvenile dermatomyositis; 20 with localized scleroderma; four with systemic sclerosis; and three with mixed connective tissue disease. Clinical and laboratory tests and nailfold capillaroscopy were performed in all patients. The nailfold capillaroscopy was performed with an optical microscope (at 10-and 16-time magnifi cations) by the same observer. Results: Most patients (76.2%) had normal nailfold capillaroscopy. The major changes in nailfold capillaroscopy, characterizing the scleroderma pattern, were observed in patients with juvenile dermatomyositis, systemic scleroderma and mixed connective tissue disease. There was no association between nailfold capillaroscopy and disease activity in patients with juvenile idiopathic arthritis, systemic lupus erythematosus and localized scleroderma. Disease activity and capillaroscopy were associated in patients with juvenile dermatomyositis. Conclusion: Nailfold capillaroscopy is a useful method to diagnose autoimmune rheumatic diseases and monitor disease activity.

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Section: Discussionmentioning

confidence: 85%

Capilaroscopia periungueal em crianças e adolescentes com doenças reumáticas

Piotto¹,

Len²,

Hilário³

et al. 2012

Rev. Bras. Reumatol.

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“…NC abnormalities are associated with skin involvement in untreated patients with DM 3 and seem also to correlate with disease activity in inflammatory myopathies 1,2 . DM-specific NC changes in a scleroderma-like pattern 8 provide useful information that contributes to an early diagnosis and helps identify those cases with a poor prognosis 4 .…”

Section: Rheumatologymentioning

confidence: 99%

“…Severe nailfold capillaroscopy (NC) findings have been described but their association with disease activity and/or response to treatment have rarely been investigated [1][2][3][4][5][6][7] .…”

mentioning

confidence: 99%

Successful Immunosuppressive Treatment of Dermatomyositis: A Nailfold Capillaroscopy Survey

Riccieri

Vasile²,

Macri³

et al. 2010

J Rheumatol

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“…In studies with juvenile DM, the SD pattern is most common, having a positive association with severity and clinical and laboratory activity of the disease. [39][40][41] Mixed connective tissue disease RP is one of the initial manifestations of the disease, occurring in approximately 85% of patients with MCTD and is also part of the main classification criteria for this disease. 42 SD pattern is observed in 50-65% of cases.…”

Section: Dermatomyositis and Polimyositismentioning

confidence: 99%

Nailfold capillaroscopy: relevance to the practice of rheumatology

Souza

Kayser

2015

Revista Brasileira de Reumatologia (English Edition)

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r e v b r a s r e u m a t o l . 2 0 1 5;5 5(3):264-271 w w w . r e u m a t o l o g i a . c o m . b r a b s t r a c t Nailfold capillaroscopy is a simple, low-cost method, that is extremely important in the evaluation of patients with Raynaud's phenomenon and of patients with systemic sclerosis (SSc) spectrum diseases. Besides its importance for the early diagnosis of SSc, nailfold capillaroscopy is a useful tool to identify scleroderma patients with high risk for development of vascular and visceral complications and death. The inclusion of capillaroscopy in the new classification criteria for SSc of the American College of Rheumatology (ACR) and European League Against Rheumatism (Eular) gives a new impetus to the use and dissemination of the method. In this paper, we present a didactic, non-systematic review on the subject, with emphasis on advances recently described. Capilaroscopia periungueal: relevância para a prática reumatológica Palavras-chave: Capilaroscopia Fenômeno Raynaud Esclerose sistêmica r e s u m o A capilaroscopia periungueal é um método simples, de baixo custo, e de extrema relevância na avaliação de pacientes com fenômeno de Raynaud ou portadores de doenças do espectro da esclerose sistêmica (ES). Além de sua importância para o diagnóstico precoce da ES, constitui instrumento útil na identificação de pacientes esclerodérmicos com risco elevado para o desenvolvimento de complicaç ões vasculares, viscerais e de óbito. A inclusão da capilaroscopia nos novos critérios para classificação da ES do Colégio Americano de Reumatologia (ACR) e da Liga Europeia Contra o Reumatismo (Eular) dá novo impulso para a utilização e disseminação do método. No presente artigo, pretendemos apresentar uma revisão didática, não sistemática, sobre o tema, com ênfase nos avanços recentemente descritos. r e v b r a s r e u m a t o l . 2 0 1 5;5 5(3):264-271

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Inflammatory myopathies in childhood: correlation between nailfold capillaroscopy findings and clinical and laboratory data

Abstract: Nailfold capillaroscopy is a non-invasive examination that offers satisfactory correlation with disease activity and could be a useful tool for the diagnosis and follow-up of inflammatory myopathies.

Cited by 32 publications

References 21 publications

Capilaroscopia periungueal em crianças e adolescentes com doenças reumáticas

Capilaroscopia periungueal em crianças e adolescentes com doenças reumáticas

Successful Immunosuppressive Treatment of Dermatomyositis: A Nailfold Capillaroscopy Survey

Nailfold capillaroscopy: relevance to the practice of rheumatology

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